Expression vector suitable for expressing coded sequence used for gene therapy

A coding sequence and expression cassette technology, which is applied in the field of expression vectors for gene therapy, can solve problems such as reduced activity
CN102628041BActive Publication Date: 2013-09-11MOGAM BIOTECH RES INST
2 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
MOGAM BIOTECH RES INST
Publication Date
2013-09-11

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

Provided is an expression vector for gene therapy. The expression vector comprises a new combination which contains a transcriptional control element and comprises a promoter, an enhancer, an intron, an untranslated region (UTR) and a loca control region (LCP). The expression vector can continuously express specific genes of hepatic tissue so that the expression vector can be effectively used in treating thrombus forming, hemophilia, liver cancer and the like.
Need to check novelty before this filing date? Find Prior Art

Description

[0001] This application is a divisional application of a Chinese patent application with application number 200880126705.0, and the original application is a Chinese national phase application of the international application PCT / KR2008 / 000870. technical field

[0002] The present invention relates to an expression vector for gene therapy, more particularly to an expression vector for gene therapy comprising a new combination of transcriptional regulatory elements (cis-regulatory elements or trans-acting elements), including promoters, enhancers, internal Containing son, untranslated region (UTR) and locus control region (locus control region, LCR), said vector can support target gene to be expressed continuously at a high level in the liver. Background technique

[0003] The functions of the liver include blood storage, glucose conversion, and secretion of various cytokines, as well as the expression of genes affecting many diseases such as genetic, cardiovascular, metabolic...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More