Micro flow control chip used for multi-index biochemical detection

A microfluidic chip and biochemical detection technology, which is applied to laboratory containers, chemical instruments and methods, laboratory utensils, etc., can solve the problems of high price, slow test speed, complicated operation, etc., and achieve huge economic value and Social value, reducing sample and reagent consumption, and simplifying the operation process

Active Publication Date: 2012-09-19
CAPITALBIO CORP +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the existing semi-automatic or fully automatic biochemical analyzers have been widely used by medical testing institutions, these instrument systems are often bulky, expensive, complicated to operate, and slow in testing speed, so it is impossible to carry out real-time and rapid on-site instant testing
In addition, the matching biochemical reaction kits are also expensive and complicated to operate

Method used

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  • Micro flow control chip used for multi-index biochemical detection
  • Micro flow control chip used for multi-index biochemical detection
  • Micro flow control chip used for multi-index biochemical detection

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Embodiment Construction

[0032] The present invention will be further described below in conjunction with the drawings, but the present invention is not limited to the following embodiments.

[0033] Such as figure 1 As shown, the microfluidic chip for multi-index biochemical detection provided by the present invention includes a microfluidic channel 2, three reaction cells 3, and a pneumatic microvalve; one open end of the microfluidic channel 2 is the injection port 1, the other The open end communicates with a chamber 4 provided in the microfluidic chip. One side wall of the chamber 4 is an elastic film 5 and is exposed to the air. The material is PDMS with a thickness of 200 μm; 3 reaction cells 3 Enzymes and substrates needed for biochemical reactions (such as figure 1 As shown in (a)), the three reaction cells are connected in series through the microfluidic channel 2; the pneumatic microvalve includes a control channel 6, one side wall of the control channel 6 is an elastic film 7, and its material...

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Abstract

The invention discloses a micro flow control chip used for multi-index biochemical detection. The micro flow control chip comprises a micro-fluid channel, a plurality of reaction tanks and a pneumatic micro-valve, wherein one opening end of the micro-fluid channel is a sample inlet while the other opening end is communicated with a chamber arranged in the micro flow control chip; the top wall of the chamber is an elastic film and is exposed in air; reaction tanks are connected in series or in parallel through the micro-fluid channel; the pneumatic micro-valve comprises a control channel; one sidewall of the control channel is an elastic film; and the control channel and the micro-fluid channel are arranged crossly. The micro flow control chip used for multi-index biochemical detection integrates sample introduction with multi-index biochemical reaction based on a micro flow control chip technical platform, so that the micro flow control chip used for multi-index biochemical detection, disclosed by the invention, has the advantages of greatly simplifying operating process, reducing consumption of samples and reagents, having no need to allocate expensive instruments, greatly reducing use cost, making on-site instant detection possible and having great foreseeable economic value and social value.

Description

Technical field [0001] The invention relates to a microfluidic chip for multi-index biochemical detection, and relates to the technical field of microfluidic chips. Background technique [0002] Biochemical analysis methods determine the concentration of trace components contained in blood or other body fluids, and provide doctors with a basis for clinical diagnosis, which is closely related to people's health and safety. In the process of analysis and detection of complex biochemical samples, due to the nature of certain target analytes or the limitations of the detector, ideal signals cannot be obtained through direct detection. In order to achieve the purpose of detection, it is an extremely common processing method to transform it into a strong signal substance matching the sensor or detector through a biochemical reaction. At present, conventional biochemical analyzers are based on the detection principle of spectrophotometry, and carry out enzymatic or immune reaction kine...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
Inventor 叶嘉明张凯欢邢婉丽程京
Owner CAPITALBIO CORP
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