Synthetic decapeptide and method for promoting generation of fish yolk

A technology for yolk formation and fish, which is applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, peptides, etc., and can solve the problems of short reproductive season, scarce sources of seedlings, and unfavorable artificial seedling cultivation.

Active Publication Date: 2012-09-19
NAT PINGTUNG UNIV OF SCI & TECH
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Problems solved by technology

[0004] From the above, both the gonadotropin-releasing hormone (GnRH) secreted by the hypothalamus and the gonadotropin (GtH) secreted by the pituitary gland are the main factors that stimulate the reproductive development of fish, and the artificial reproduction of existing species of fish mostly uses the pituitary gland. Injection method (Hypophysation), that is, treatment with gonadotropin (GtH) to obtain the expected oviposition result, however, this GtH has inter-species differences and cannot be obtained synthetically. If it is produced by genetic engineering, the cost will be high. Therefore, the scope of use is limited; and the most commonly used hormone preparations in the aquaculture industry currently include human chorionic gonadotropin (Human Chorionic Gonadotropin; hCG) and commercial hormone mixture preparations in addition to pituitary gland extracts or purified preparations containing GtH components. [Mixed by LHRHA and dopamine antagonist (Domperidome)], the use of both is to promote the final maturation of mature fish egg cells, that is, the process from the third yolk stage to ovulation and spawning. However, the above-mentioned various hormone preparations cannot Promote the early development of cultured fish egg cells, that is, it cannot induce and promote the yolk production of cultured fish. Therefore, for the short reproductive season, it is difficult to mature naturally under artificial breeding conditions, and the mature state is unstable. The reproductive season is not conducive to artificial It is not easy to establish a technology for effective control of spawning and mass production of seedlings for seedling cultivation or aquaculture fish with scarce source of seedlings, which is the bottleneck in the development of today's aquaculture industry

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  • Synthetic decapeptide and method for promoting generation of fish yolk
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  • Synthetic decapeptide and method for promoting generation of fish yolk

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Embodiment Construction

[0018] In order to make the above-mentioned and other objects, features and advantages of the present invention more comprehensible, the preferred embodiments of the present invention are specifically cited below, together with the accompanying drawings, as follows:

[0019] The present invention is a synthetic peptide that promotes the production of yolk in fish. It is a peptide (decapeptide) composed of ten amino acids. The sequence of the synthetic peptide is referenced from a naturally secreted peptide of a poultry (such as chicken, duck or goose, etc.). GnRH-II sequence; this synthetic peptide can induce and promote vitellogenesis in teleost fish. Implanting the synthetic peptide into the body wall or body cavity of a bony fish can effectively promote the production and accumulation of yolk in the bony fish, promote the maturation of female breeding fish, and regulate the reproductive season of the female breeding fish of the bony fish.

[0020] More specifically, the syn...

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Abstract

The invention discloses a synthetic decapeptide for promoting generation of fish yolk. The synthetic decapeptide is the decapeptide consisting of ten amino acids and is shown by a sequence identification number 2. The synthetic decapeptide refers to GnRH-II naturally secreted by a type of poultry. The invention discloses a preparation for promoting generation of fish yolk, wherein the preparation comprises the synthetic decapeptide. The invention discloses a method for promoting generation of fish yolk, wherein the method comprises the following steps of: implanting the preparation in a body wall or body cavity of teleostean; and promoting maturation of the teleostean yolk.

Description

technical field [0001] The present invention relates to a synthetic peptide and its application, especially a synthetic peptide that can promote fish yolk production, and its application in inducing and promoting the maturation of fish species. Background technique [0002] Taiwan's aquaculture industry has a long history of development. In the past two decades, the rapid development and growth of the aquaculture industry has been driven by the technological advancement of aquaculture technology and the diversification of aquaculture species. Most of the early fish farming in Taiwan was in the form of extensive polyculture, and the source of seedlings was mostly dependent on fishing, so the quantity, source and quality of seedlings were unstable and could not meet the needs of industrial development; in recent years, due to seedling cultivation technology and artificial The establishment of bait promotes the intensification and commercialization of aquaculture. The intensive...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07K7/06A61K38/08A61K9/00A61K47/38A61P15/08
Inventor 陈英男
Owner NAT PINGTUNG UNIV OF SCI & TECH
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