Thin-layer identification method of leonurus in Yi Xue An particles

A thin-layer identification and Yixuean technology, applied in measuring devices, instruments, scientific instruments, etc., can solve the problems of effective control of drug quality, and the analysis method of motherwort has not yet been established.

Active Publication Date: 2013-02-20
广西万寿堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the existing quality standards for Yixuan Granules, no analysis method for motherwort has been established, so it is

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Take 15g of finished Yixuean granules, add 300ml of cold absolute ethanol, shake and extract for 30min, filter, evaporate the filtrate to dryness, add 4ml of absolute ethanol to dissolve the residue, and use it as the test solution;

[0014] Take an appropriate amount of stachydrine hydrochloride reference substance, add absolute ethanol to make a solution containing 0.1mg per 1ml as the reference substance solution;

[0015] According to the thin-layer chromatography experiment of appendix VIB of "Chinese Pharmacopoeia" 2010 edition, draw respectively 10 μ l of the test solution and the reference solution, respectively spot on the same silica gel G thin-layer plate, with a volume ratio of 6:6: 1 mixed solution of acetone, absolute ethanol, and concentrated hydrochloric acid is developed as a developing agent, taken out, dried, sprayed with improved bismuth iodide potassium chromogen, and heated to make the spots clear in color. On the corresponding position of...

Embodiment 2

[0017] Take 15g of finished Yixuean granules, add 200ml of cold absolute ethanol, shake and extract for 30min, filter, evaporate the filtrate to dryness, add 2ml of absolute ethanol to dissolve the residue, and use it as the test solution;

[0018] Take an appropriate amount of stachydrine hydrochloride reference substance, add absolute ethanol to make a solution containing 0.1mg per 1ml as the reference substance solution;

[0019] According to the thin-layer chromatography experiment of appendix VIB of "Chinese Pharmacopoeia" 2010 edition, draw respectively 10 μ l of the test solution and the reference solution, respectively spot on the same silica gel G thin-layer plate, with a volume ratio of 6:6: 1 mixed solution of acetone, absolute ethanol, and concentrated hydrochloric acid is developed as a developing agent, taken out, dried, sprayed with improved bismuth iodide potassium chromogen, and heated to make the spots clear in color. On the corresponding position ...

Embodiment 3

[0021] Take 15g of finished Yixuean granules, add 300ml of cold absolute ethanol, shake and extract for 30min, filter, evaporate the filtrate to dryness, add 3ml of absolute ethanol to dissolve the residue, and use it as the test solution;

[0022] Take an appropriate amount of stachydrine hydrochloride reference substance, add absolute ethanol to make a solution containing 0.1mg per 1ml as the reference substance solution;

[0023] According to the thin-layer chromatography experiment of appendix VIB of "Chinese Pharmacopoeia" 2010 edition, draw respectively 10 μ l of the test solution and the reference solution, respectively spot on the same silica gel G thin-layer plate, with a volume ratio of 6:6: 1 mixed solution of acetone, absolute ethanol, and concentrated hydrochloric acid is developed as a developing agent, taken out, dried, sprayed with improved bismuth iodide potassium chromogen, and heated to make the spots clear in color. On the corresponding position ...

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Abstract

The invention discloses a thin-layer identification method of leonurus in Yi Xue An particles. The method takes stachydrine hydrochloride as a comparison, and takes the mixed solution acetone, absolute ethyl alcohol and concentrated hydrochloric acid as a developing solvent. The thin-layer identification method of leonurus in Yi Xue An particles established by the invention is simple to operate, is rapid and practical, provides reliable ensurance for controlling the quality of Yi Xue An particles effectively, and thus the thin-layer identification method of leonurus in Yi Xue An particles can have a stable, reliable and accurate curative effect.

Description

technical field [0001] The invention belongs to the TLC identification technology of motherwort in medicine, in particular to a thin-layer identification method of motherwort in Yixuan granules. Background technique [0002] Yixue'an granule is a Chinese patent medicine for treating gynecological hyperemia. It can be used for the treatment of postpartum and post-abortion uterine insufficiency, postpartum lochia, and menorrhagia. Motherwort is a blind drug in Yixuan Granules, which plays a certain role in its therapeutic effect. However, in the existing quality standards for Yixuan Granules, the analysis method for Motherwort has not been established, and it is difficult to more effectively control the quality of the drug so that it can exert a stable, reliable and definite curative effect. Contents of the invention [0003] The technical problem to be solved by the present invention is to provide a simple, quick and practical method for TLC identification of motherwort in...

Claims

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Application Information

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IPC IPC(8): G01N30/90
Inventor 许振朝覃爱环蒋冰清凌菲琳
Owner 广西万寿堂药业有限公司
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