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Inhalation preparation for treating asthma

A technology for inhalation preparations, asthma, applied in the field of medicine, which can solve problems such as little research

Inactive Publication Date: 2013-03-13
FOSHAN YIBAOSHENG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The currently marketed inhaled anticholinergics include ipratropium bromide, tiotropium bromide, glycopyrronium bromide, etc. There are other anticholinergics that have not been used in the treatment of asthma, and there are few related studies

Method used

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  • Inhalation preparation for treating asthma
  • Inhalation preparation for treating asthma
  • Inhalation preparation for treating asthma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Embodiment 1 dry powder inhaler

[0012] prescription:

[0013]

[0014] Preparation:

[0015] Mix vecuronium bromide, lactose 8g, and magnesium stearate thoroughly and evenly. The particle size of the micropowder is D90 less than 7 microns, and the obtained mixed powder is baked at 70 degrees for 12 hours, and filled into the No. 3 capsule shell.

Embodiment 2

[0016] Embodiment 2 dry powder inhaler

[0017] prescription:

[0018]

[0019] Preparation:

[0020] Mix pancuronium bromide, lactose 8g, and magnesium stearate thoroughly and evenly. The particle size of the micropowder is D90 less than 7 microns, and the obtained mixed powder is baked at 70 degrees for 12 hours, and filled into the No. 3 capsule shell.

Embodiment 3

[0021] Embodiment 3: Aerosol

[0022] prescription:

[0023]

[0024] Preparation:

[0025] Dissolve pancuronium bromide in ethanol, dispense quantitatively into aerosol containers after dissolving, install valves, tighten caps, and fill propellants to obtain the product.

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Abstract

The invention relates to an inhalation preparation for treating asthma. The inhalation preparation is prepared by taking one of otilonium bromide, oxyphenonium bromide, pipecuronium bromide, rocuronium bromide, pancuronium bromide, pinaverium bromide and vecuronium bromide as active ingredient and mixing pharmaceutical-accepted auxiliary materials. The inhalation preparation includes but is not limited to dry powder inhaler, aerosol and spray.

Description

technical field [0001] The invention relates to an inhalation preparation for treating asthma, belonging to the technical field of medicine. Background technique [0002] Asthma is a chronic airway inflammation involving a variety of cells, especially mast cells, eosinophils, and T lymphocytes; in susceptible individuals, this inflammation can cause recurrent wheezing, shortness of breath, chest tightness, and / or coughing Symptoms, mostly at night or early in the morning; these symptoms are often accompanied by extensive and variable expiratory flow limitation, but can be partially relieved naturally or treated; this symptom is also accompanied by airway response to various stimuli Increased reactivity. The prevalence and mortality of asthma in foreign countries are gradually increasing, and there are about 100 million asthma patients in the world, becoming a major chronic disease that seriously threatens people's health. The incidence rate of asthma in my country is 1%, a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/72A61K31/245A61K31/58A61K31/5375A61P11/06
Inventor 不公告发明人
Owner FOSHAN YIBAOSHENG PHARMA CO LTD
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