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Multi-channel mixing ionization source and working method thereof

A working method and ionization source technology, applied in the field of ionization sources, can solve problems such as complexity, lack of highly reliable consistency in detection performance, and inability to realize simultaneous analysis of two types of substances, so as to achieve the effect of improving detection efficiency

Inactive Publication Date: 2013-03-13
FOCUSED PHOTONICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In more application fields, to analyze different substances, different gas chromatographic columns need to be used, and the chromatographic and mass spectrometer instruments need to be switched off to replace the chromatographic column. This replacement process is often complicated, and the detection performance after restarting is often not highly reliable consistency
[0004] In many analysis and detection fields, the above-mentioned mass spectrometry problems will be encountered. For example, the detection of strong polar and weak polar organic substances requires replacement of the chromatographic column. In order to obtain the molecular ion information of the substance, the ion source needs to be replaced. In some GC-MS instruments, Realized double-column sampling, that is, installed two chromatographic columns in the same set of column thermostat system, and inserted the two chromatographic columns into one ion source at the same time. Simultaneous analysis of two classes of substances

Method used

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  • Multi-channel mixing ionization source and working method thereof

Examples

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Embodiment 1

[0026] figure 1 Schematically provides a simplified structural diagram of the multi-channel hybrid ionization source of the embodiment of the present invention, as figure 1 As shown, the ionization source includes:

[0027] It includes an ion transmission channel, and the transmission channel includes a first repeller electrode 3 and an ion lens (such as three electrodes 4, 5, 6); the ion transmission channel is a prior art in the field, and will not be repeated here.

[0028] At least two ionization channels, each ionization channel includes a repelling electrode, an ion source 1, a transmission electrode and a switching electrode 2, and the repelling electrode, ion source, transmission electrode and switching electrode are all prior art in the art, here No longer. For example, the ion source may be CI ion source, EI ion source or other types of ion source. Optionally, the ion source is connected to a chromatographic column to form a chromatography-mass spectrometer.

[0...

Embodiment 2

[0035] According to the application example of the ionization source and the working method in Example 1 of the present invention, it is specifically applied to the analysis of organic matter in a chromatography-mass spectrometer. In this application example, there are two ionization channels with an included angle of 180 degrees, and the ion source of each ionization channel is connected to the chromatographic column to directly ionize the object to be measured. The ion source of the two ionization channels adopts CI ion source and EI ion source respectively, and one electrode is used for the transmission electrode and switching electrode in each channel, so as to apply to different detection requirements. The angle between the two ionization channels and the ion transmission channel is 90 degrees, and the voltages applied on the three electrodes of the repelling electrode, the transmitting electrode, the first repelling electrode and the ion lens in the ionization channel are...

Embodiment 3

[0038] According to the application example of the ionization source and the working method in Example 1 of the present invention, it is specifically applied to the analysis of organic matter in a chromatography-mass spectrometer. In this application example, there are four ionization channels with adjacent angles of 90 degrees, and the ion source of each ionization channel is connected to the chromatographic column to directly ionize the object to be measured. The ion source of the two ionization channels adopts CI ion source or EI ion source, so as to apply to different detection requirements. The included angle between the four-way ionization channel and the ion transmission channel is 120 degrees, and a voltage is applied to the three electrodes of the ionization channel, the repelling electrode, the transmitting electrode, the first repelling electrode, and the ion lens, thereby realizing ionization 120 degree deflection of ions in the channel.

[0039] Under the control...

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Abstract

The invention provides a multi-channel ionization source. The ionization source comprises an ion transmission channel and at least two ion channels, wherein the transmission channel comprises a first repulsion electrode and an ion lens, each of the ion channels comprises a repulsion electrode, an ionization source, a transmission electrode and a switching electrode, the included angle formed by at least two ion channels and the ion transmission channel is in a range from 0 degree to 180 degrees, and ions generated by any ionization source enter the ion lens through the transmission electrodes and the switching electrodes under the action of the transmission electrodes, the first repulsion electrode and the repulsion electrodes of the ion channels. The switching is automatic, and a plurality of objects are detected at the same.

Description

technical field [0001] The invention relates to an ionization source, in particular to a multi-channel ionization source and its working method. Background technique [0002] Gas chromatography-mass spectrometry instrument is one of the important members in the field of analytical instruments. The mixed organic molecules enter the mass spectrometer after being separated by the gas chromatography column. The mass spectrometer ionizes the organic molecules and makes various ions under the action of electric field or magnetic field. Separation is carried out according to the mass-to-charge ratio, and the corresponding intensity is detected. The obtained mass spectrum signal can be used for qualitative identification and quantitative analysis of substances. [0003] The mass spectrometer detector used to connect with the gas chromatograph usually has two kinds of ion sources, electron ionization (EI) source and chemical ionization (CI). There are certain differences in the struc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): H01J49/10H01J49/16H01J49/14
CPCH01J49/107
Inventor 吴先伟刘立鹏马辉邓丰涛
Owner FOCUSED PHOTONICS
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