Application of coffee residue extract in preparing medicaments
A technology of extract and waste residue, applied in the field of pharmacy
Inactive Publication Date: 2013-03-27
HAINAN MEDICAL COLLEGE
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Problems solved by technology
As environmental protection and low carbon gradually become the mainstream concept in the world, the waste utilization research of coffee grounds has made great progress. For example, scientists in Japan and the United States use coffee waste to extract biodiesel; other literature reports that coffee grounds extract has antioxidant effect And sugar can be extracted from coffee waste, but the preparation of extract from coffee waste for anti-inflammation has not been reported yet
Method used
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Effect test
Embodiment 1
[0042] Take 400g of waste coffee grounds, add 8000ml of 50% ethanol, heat and reflux extraction for 3 times, each time for 1h, collect the filtrate by filtration, and recover ethanol with a rotary evaporator until the extract has no alcohol smell and becomes a thick paste.
Embodiment 2
[0044] Take 400g of coffee waste, add 4000ml of 80% ethanol, heat and reflux for extraction for 1 hour, collect the filtrate by filtration, recover the ethanol until the extract has no alcohol smell, and concentrate to a thick paste.
Embodiment 3
[0046] Take 400g of coffee waste, add 3200ml of 95% ethanol, heat and reflux for extraction twice, the first extraction for 2 hours, the second extraction for 1 hour, filter and collect the filtrate, recover the ethanol until the extract has no alcohol smell, and concentrate to a thick paste.
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The invention provides application of coffee residue extract in preparing medicaments. The invention relates to an extract obtained from coffee residues and application thereof in preparing a medicament, and belongs to the field of medicine. Thin-layer identification indicates that the extract mainly comprises triterpene compounds, and has an inhibition effect to increased permeability of mouse peritoneal capillary, can be used for reducing the dimethylbenzene induced mouse ear swelling rate, and has certain anti-inflammation effect. According to the application, residues are utilized, and the coffee residue extract is applied to medicament preparation.
Description
Technical field: [0001] The invention relates to the extraction and separation of an extract containing triterpenes from coffee waste residues and its application in the preparation of medicines, which belongs to the field of pharmacy. Background technique: [0002] While producing instant coffee, instant coffee factories produce a large amount of coffee waste residues, which are mostly treated as garbage. According to the statistics of the United States Department of Agriculture, about 7 billion kilograms of coffee is produced in the world every year. After the coffee is eaten or extracted, the amount of coffee waste produced is extremely considerable. As environmental protection and low carbon gradually become the mainstream concept in the world, the waste utilization research of coffee grounds has made great progress. For example, scientists in Japan and the United States use coffee waste to extract biodiesel; other literature reports that coffee grounds extract has antio...
Claims
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IPC IPC(8): A61K36/74A61P29/00
Inventor 张俊清廖小平谭银丰苏文琴
Owner HAINAN MEDICAL COLLEGE