Acoustic surface wave accelerated headspace single-drop microextraction device and acoustic surface wave accelerated headspace single-drop microextraction method

Abstract

The invention discloses an acoustic surface wave accelerated headspace single-drop microextraction device and an acoustic surface wave accelerated headspace single-drop microextraction method. The microextraction device comprises a piezoelectric substrate, a microsyringe used for suspending an organic extraction agent liquid drop, a cover body and a signal generation device used for generating an RF (radio frequency) electrical signal, wherein the upper surface of the piezoelectric substrate is a working surface; the working surface is provided with interdigital transducers and a hydrophobic layer used for placing an extraction liquid sample liquid drop; the extraction liquid sample liquid drop is positioned on a sound transmission path of an acoustic surface wave excited by the interdigital transducers; the opening end of the cover body is inversely buckled on the hydrophobic layer; the extraction liquid sample liquid drop is positioned in the cover body; a needle point of the microsyringe penetrates through the bottom of the cover body and extends into the cover body; and the distance between the organic extraction agent liquid drop and the extraction liquid sample liquid drop is 0.5-1 centimeters. By utilizing the acoustic surface wave accelerated headspace single-drop microextraction device and the acoustic surface wave accelerated headspace single-drop microextraction method, movement of the extraction liquid sample liquid drop is driven by utilizing the acoustic surface wave excited by the interdigital transducers so that the extraction speed is increased, and extractants in the extraction liquid sample liquid drop are sufficiently volatilized so that the extraction degree is improved.

Description

technical field [0001] The invention relates to a micro-extraction technology in a microfluidic device, in particular to a headspace single-droplet micro-extraction device and method accelerated by surface acoustic waves. Background technique [0002] Liquid-liquid microextraction is one of the most commonly used sample pretreatment techniques in biochemical analysis, and is widely used in the analysis of trace substances. Single-droplet microextraction technology has become a commonly used extraction technique for liquid-liquid microextraction due to its advantages of simple extraction equipment, less consumption of organic solvents and short extraction time, which overcomes the problems of traditional liquid-liquid microextraction such as Disadvantages such as large consumption of organic solvent and relatively low degree of extraction. [0003] Some scientific researchers have proposed a direct immersion single-droplet microextraction technology, which directly immerses ...

AI Technical Summary

Problems solved by technology

However, due to the large volume of the stirring equipment, it is difficult to organically combine with the microfluidic device, so this method is not conducive to microfluidic operation, and needs to be further improved

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