Arthritis-relieving dropping pill for treating osteoarthrosis and preparation method thereof

A technology for osteoarthritis and Ningdrop pills, which is applied in the field of medicine, can solve problems such as difficult quality control, inconvenient carrying and use, and achieve the effects of low cost, accurate single dose, and simple process equipment

Active Publication Date: 2013-07-03
TIANJIN INSTITUTE OF PHARMA RESEARCH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional water decoctions are inconvenient to carry and use, and the quality is difficult to control

Method used

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  • Arthritis-relieving dropping pill for treating osteoarthrosis and preparation method thereof
  • Arthritis-relieving dropping pill for treating osteoarthrosis and preparation method thereof
  • Arthritis-relieving dropping pill for treating osteoarthrosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] Embodiment 1, the preparation of Tongbining dropping pills

[0061] 1. Prescription: Zhichuan Aconitum 1.3g, Fuzi (made) 2.7g, Dried Ginger 4g, Cinnamon 2.7g, Zanthoxylum bungeanum 1.3g, Duhuo 5.3g, Paeoniae Alba 2.7g, Asarum 1.3g, Fangfeng 4g, Gentiana 2.7g, Poria cocos 4g, angelica 4g, jujube 1.3g, licorice (burnt) 2.7g

[0062] 2. Preparation method:

[0063] (1) Medicinal material extraction: Weigh 20 times the prescription amount of Asarum, Zanthoxylum bungeanum, Cinnamon, Dried Ginger, Fangfeng, Angelica, Duhuo, etc., add 10 times the amount (volume / weight) of water and soak for 2 hours, steam distillation method Extract for 8 hours, collect volatile oil, obtain extract I, and set aside; take 20 times of the above-mentioned prescription amount to prepare 7 flavors such as Aconitum Aconitum, Aconite (made), Radix Paeoniae Alba, Gentiana officinalis, Poria, Jujube, Radix Glycyrrhizae (burned), etc., use 10 Double the amount (volume / weight) of 70% ethanol to reflux...

Embodiment 2

[0068] Embodiment 2, the preparation of Tongbining dripping pills

[0069] 1. Prescription: Zhichuan Aconitum 1.3g, Fuzi (made) 2.7g, Dried Ginger 4g, Cinnamon 2.7g, Zanthoxylum bungeanum 1.3g, Duhuo 5.3g, Paeoniae Alba 2.7g, Asarum 1.3g, Fangfeng 4g, Gentiana 2.7g, Poria cocos 4g, angelica 4g, jujube 1.3g, licorice (burnt) 2.7g

[0070] 2. Preparation method:

[0071] (1) Medicinal material extraction: Weigh 20 times the prescription amount of Asarum, Zanthoxylum bungeanum, Cinnamon, Dried Ginger, Fangfeng, Angelica, Duhuo, etc., add 10 times the amount (volume / weight) of water and soak for 2 hours, steam distillation method Extract for 8 hours, collect volatile oil, obtain extract I, and set aside; take 20 times of the above-mentioned prescription amount to prepare 7 flavors such as Aconitum Aconitum, Aconite (made), Radix Paeoniae Alba, Gentiana officinalis, Poria, Jujube, Radix Glycyrrhizae (burned), etc., use 10 Double the amount (volume / weight) of 70% ethanol to reflux...

Embodiment 3

[0076] Embodiment 3, the preparation of Tongbining dropping pills

[0077] 1. Prescription: Aconitum 1.3g, Aconite (made) 2.7g, Dried ginger 4g, Cinnamon 2.7g, Zanthoxylum bungeanum 1.3g, Duhuo 5.3g, Paeoniae Alba 2.7g, Asarum 1.3g, Fangfeng 4g, Gentiana 2.7g, Poria cocos 4g, angelica 4g, jujube 1.3g, licorice (burnt) 2.7g

[0078] 2. Preparation method:

[0079] (1) Medicinal material extraction: Weigh 20 times the prescription amount of Asarum, Zanthoxylum bungeanum, Cinnamon, Dried Ginger, Fangfeng, Angelica, Duhuo, etc., add 10 times the amount (volume / weight) of water and soak for 2 hours, steam distillation method Extract for 8 hours, collect volatile oil, obtain extract I, and set aside; take 20 times of the above-mentioned prescription amount to prepare 7 flavors such as Aconitum Aconitum, Aconite (made), Radix Paeoniae Alba, Gentiana officinalis, Poria, Jujube, Radix Glycyrrhizae (burned), etc., use 10 Double the amount (volume / weight) of 70% ethanol to reflux and ext...

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Abstract

The invention discloses an arthritis-relieving dropping pill for treating osteoarthrosis and a preparation process of the dropping pill. The dropping pill is prepared from refined extract of traditional Chinese medicinal materials with doses, polyethylene glycol substrate and other auxiliaries, wherein the weight part ratio of the refined extract to the polyethylene glycol substrate to the other auxiliaries is 20-60 to 20-100 to 0-5; the refined extract comprises two parts of components; one part of component is prepared by steam distillation or supercritical extraction, while the other part is prepared by extracting with ethanol, water or mixed solvent of water and ethanol. The taking dose of the arthritis-relieving dropping pill is low, so that the dropping pill can be easily accepted and taken by a patient, and the dropping pill has the characteristics of quick dissolving speed, facilitation in body absorption, and stable quality.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a traditional Chinese medicine Tongbining dripping pill for treating osteoarthritis and a preparation method thereof, in particular to a medicine containing Aconitum Aconitum, Asarum, Zanthoxylum bungeanum, Radix Glycyrrhizae (burned), Gentiana officinalis, Aconite (system), cinnamon, white peony root, dried ginger, poria cocos, windproof, angelica, duhuo, jujube ("Aconitou decoction prescription") and other Chinese medicine dripping pills made from extracts and preparation methods thereof. Background technique [0002] Osteoarthropathy is a common disease in middle-aged and elderly people with joint pain and joint dysfunction (including joint deformity) caused by degeneration of articular cartilage. Also known as osteoarthritis. Commonly affected joints include hands, knees, cervical spine, lumbar spine, and hip joints, including bone spurs, hyperosteogeny, bowed legs, cervical ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/20A61P19/02A61P29/00
Inventor 张铁军龚苏晓孙卫廖茂梁王丽莉
Owner TIANJIN INSTITUTE OF PHARMA RESEARCH
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