Device and method of achieving digital microfluid cracking of acoustic surface waves

Abstract

The invention discloses a device and method of achieving digital microfluid cracking of acoustic surface waves. The device comprises a piezoelectric substrate and a signal generating device. An interdigital transducer used for stimulating the acoustic surface waves, a first hydrophobic layer used for placing digital microfluid to be cracked, a sound absorption coating used for attenuating the intensity of the acoustic surface waves simulated by the interdigital transducer and a second hydrophobic layer used for receiving cracked digital microfluid are arranged on the piezoelectric substrate. The first digital microfluid, the sound absorption coating and the second digital microfluid are sequentially located on sound transmission paths of the acoustic surface waves. When the power of an RF electrical signal loaded on the interdigital transducer by the signal generating device is instantaneously reduced, and is greater than or equals to 15dBm, the digital microfluid cracks, and the cracked digital microfluid flies out and drops on the second hydrophobic layer. The device has the advantages that the interdigital transducer which is not weighted is adopted, and therefore cracking of the interdigital transducer can be achieved with low power electrical signal power. In addition, the device is simple in structure and small in size and easy to be integrated.

Description

technical field [0001] The invention relates to a digital microfluid rupture technology in a microfluidic chip, in particular to a device and method for realizing digital microfluid rupture by surface acoustic waves. Background technique [0002] Microfluidic technology can integrate a series of sampling, sample pretreatment, separation, reaction, detection and data analysis on a microfluidic substrate, which greatly reduces the cost of microfluidic analysis and shortens the time of microfluidic analysis, thus obtaining developed rapidly. Correspondingly, microfluidic analysis systems based on microfluidic technology have gradually been widely used, especially in disease diagnosis, medical and health, etc., which require expensive analytical reagents, expensive analytical instruments, and relatively high requirements for analysis time and analysis accuracy. The occasion is applied. Compared with the traditional analysis system, the microfluidic analysis system has many ad...

AI Technical Summary

Problems solved by technology

This method of fracturing digital microfluidics requires high electrical signal power, so piezoelectric ceramics are often used as substrates. However, in piezoelectric microfluidic systems, lithium niobate with a large electromechanical coupling coefficient and low cost is generally used. If the surface acoustic wave is excited by such a high-power electrical signal, the lithium niobate substrate is easily broken; at the same time, the design of the focusing interdigital transducer is relatively complicated, so the surface acoustic wave rupture digital microfluidic The method is difficult to popularize and apply

Images