489 results about "Cross-flow filtration" patented technology

Cross flow filtration cartridges are made using semipermeable membrane of sheet formation that was cast upon an integral polymeric fibrous support material which exhibits excellent permeate flow in the plane thereof and serves as both backing material and permeate carrier. A fibrous support having a thickness between about 0.4 mm and about 2 mm and at least one surface region with a mean pore size no greater than about 300 microns has a semipermeable membrane cast in situ thereupon from a liquid solution. After gelling to form a polymeric semipermeable membrane, the product is spirally wound about a porous tube in association with feed-passageway-providing sheet material, but in the absence of any separate permeate carrier, to form an effective cross-flow filtration cartridge wherein the feed flow may be spiral and the permeate discharge through one of the side edges.

A cross flow filtration apparatus for nanofiltration or reverse osmosis has pressure vessels with a plurality of filter cartridges in each vessel. A feed port is provided at an intermediate position on the side of the vessel, and two permeate flows or branches exit opposite ends of the vessel, and the first branch has a characteristically high “upstream” flux and quality, while the second is of lesser flux and / or quality. The system provides a high degree of moduarity, enhancing flux or yield at a reduced driving pressure or overall pressure drop. Centered or off-center port, and a stop or valve in the permeate stream may apportion flows between the two outlets. Staged systems may employ a first stage bypass to achieve a target quality with increased yield. A flow divider or adaptor permits the cartridges to fit and seal in the vessel and an installation tool or sleeve may facilitate installation or replacement of cartridges having a directional perimeter seal. A tool permits modules to be bi-directional installed in the pressure vessel. Other embodiments involve adapting a conventional vessel designed for end-to-end feed flow utilizing a restrictor, obstruction or valve inside the filter cartridge to bifurcate or otherwise split or apportion the permeate. RO elements may be modified to movably position an obstruction or valve along a string of the elements and vary the take-off to two or more permeate outlets, or to provide pressure relief valves that present different pressure conditions for different elements of a string. A pressure vessel may have an intermediate inlet, with symmetric or asymmetric branching of permeate flow to opposed ends of the vessel, enhancing permeate flux, permeate quality and / or energy efficiency.

A method measures a property of a germicidal solution in an endoscope processor spectroscopically by placing a quantity of the solution into a cuvette and passing a light therethrough. A reservoir receives a quantity of the solution and bubbles are filtered out via a cross-flow filter prior to putting a sample therefrom into the cuvette for measuring.

A membrane filtration module having a plurality of permeable, hollow membranes is disclosed. In use, a pressure differential is applied across the walls of the permeable, hollow membranes when immersed in a liquid suspension containing suspended solids. Some of the liquid suspension passes through the walls of the membranes to be drawn off as clarified liquid or permeate, and at least some of the solids are retained on or in the permeable, hollow membranes or otherwise as suspended solids within the liquid suspension. The module has a shell or similar structure that at least partially surrounds the membrane module and substantially effects retaining at least portion of fluid flowed into the membrane module.

A membrane filtration module having a plurality of permeable, hollow membranes is disclosed. In use, a pressure differential is applied across the walls of the permeable, hollow membranes when immersed in a liquid suspension containing suspended solids. Some of the liquid suspension passes through the walls of the membranes to be drawn off as clarified liquid or permeate, and at least some of the solids are retained on or in the permeable, hollow membranes or otherwise as suspended solids within the liquid suspension. The module has a shell or similar structure that at least partially surrounds the membrane module and substantially effects retaining at least portion of fluid flowed into the membrane module.

A method of accurately separating immunoglobulin monomers by subjecting an immunoglobulin solution containing at least immunoglobulin monomers and immunoglobulin aggregates to cross-flow filtration using an ultrafiltration membrane, an ultrafiltration membrane module, and a cross-flow filtration apparatus. The method can separate immunoglobulin monomers by subjecting an immunoglobulin solution containing at least immunoglobulin monomers and immunoglobulin aggregates and having an immunoglobulin concentration of 1 to 150 g / L to cross-flow filtration using an ultrafiltration membrane having a molecular weight cut-off of 100,000 or more and less than 500,000 so that immunoglobulin monomers passes through the ultrafiltration membrane with a permeability of 80% or more while achieving a fractionation performance in which the permeability ratio of immunoglobulin dimers to immunoglobulin monomers that pass through the ultrafiltration membrane is 0.20 or less.

A cross flow filtration apparatus for nanofiltration or reverse osmosis has pressure vessels with a plurality of filter cartridges in each vessel. A feed port is provided at an intermediate position on the side of the vessel, and two permeate flows or branches exit opposite ends of the vessel, and the first branch has a characteristically high “upstream” flux and quality, while the second is of lesser flux and / or quality. The system provides a high degree of moduarity, enhancing flux or yield at a reduced driving pressure or overall pressure drop. Centered or off-center port, and a stop or valve in the permeate stream may apportion flows between the two outlets. Staged systems may employ a first stage bypass to achieve a target quality with increased yield. A flow divider or adaptor permits the cartridges to fit and seal in the vessel and an installation tool or sleeve may facilitate installation or replacement of cartridges having a directional perimeter seal. A tool permits modules to be bi-directional installed in the pressure vessel. Other embodiments involve adapting a conventional vessel designed for end-to-end feed flow utilizing a restrictor, obstruction or valve inside the filter cartridge to bifurcate or otherwise split or apportion the permeate. RO elements may be modified to movably position an obstruction or valve along a string of the elements and vary the take-off to two or more permeate outlets, or to provide pressure relief valves that present different pressure conditions for different elements of a string. A pressure vessel may have an intermediate inlet, with symmetric or asymmetric branching of permeate flow to opposed ends of the vessel, enhancing permeate flux, permeate quality and / or energy efficiency.

Multivesicular liposomes are prepared at commercial scales by combining a first w / o emulsion with a second aqueous solution to form a w / o / w emulsion using a static mixer. Solvent is removed from the resulting emulsion to form multivesicular liposome-containing compositions. Further optional process steps include primary filtration and secondary cross-flow filtration. The products produced according to the processes of the invention can be produced through a series of aseptic steps.

A variety of improved hydroclone based fluid filtering systems are described. The hydroclones generally include a tank having an internal chamber and a filter (preferably a surface filter) that is positioned within the internal chamber. The filter defines a filtered fluid chamber within the internal chamber of the tank. The hydroclone may be operated such that a vortex of flowing fluid is formed between the chamber wall and the filter with the filter being located in the center of the vortex. With this arrangement, the filter acts as a cross-flow filter. In one aspect of the invention, the filter is a stepped filter. In another aspect of the invention, the filter is an surface filter, as for example, an electroformed metal surface filter. In some preferred embodiments, the openings in the filter are arranged as slots that extend substantially vertically so that they are oriented substantially perpendicular to the flow path of fluid flowing in the adjacent portion of the vortex. In another aspect of the invention, a circulating cleaning assembly is provided in the hydroclone region. The cleaning assembly is arranged to help clean the filter and is driven by the vortex of flowing fluid formed in the hydroclone region of the internal chamber. In yet another aspect of the invention, improved hydroclone intake structures are described. The described hydroclones may be used to filter water and other fluids in a wide variety of applications.

The disclosed principles for providing a chemical-free filtering of particulate down below sub-micron levels, while concentrating the particulate into a sludge. The disclosed principles integrate cross-flow filtration (i.e., micro-filtration or ultra-filtration) with a settling tank (or “weir”) to provide sequential filtration and dewatering of an aqueous media. The disclosed technique operates chemical-free and is continuous. Applications for systems and processes in accordance with the disclosed technique are wide, and include aggregate fines removal, sediment removal, replacement for clarifiers, etc.

In the method for preparation of microspheres by in-water drying method, an iterative process is employed, which comprises emulsifying a medicament-containing polymer solution (4) containing an organic solvent in an emulsifying device (1) to form an emulsion; transferring this emulsion into a microsphere storage tank (2); introducing a part of said emulsion to a cross flow filter (3) from the microsphere storage tank; and returning a liquid passing over the cross flow filter to the microsphere storage tank (2). Since a small amount of microsphere is repeatedly produced, this process permits the downsizing and airtight closing of an apparatus therefor, and further makes it possible to freely control the production scale of microsphere.

An exchange apparatus comprised of hollow thermoplastic tubes infusion bonded into a thermoplastic material is disclosed. In a preferred embodiment the hollow tubes are shaped by plaiting the tubes into cords and then thermally annealing the cords to set the crests and bends of the plait. The cords provide improved flow distribution of fluid about the hollow tube tubes in the exchange apparatus. The exchange apparatus is chemically inert and is useful for cross flow filtration, as well as heat and mass transfer in harsh chemical environments.

A self-cleaning, back-washable filter apparatus and method for use with a pumping apparatus which is at least partially immersed in fluid. A sediment removal system is disclosed for removing sediment from around a filter apparatus. The sediment removal system comprises a plurality of venturi jets configured to force sediment particles through a discharge line and away from the inlet to a filter apparatus. A filtering system is configured to direct a flow of fluid generally parallel to the surface of the filter, which may be a cross-flow filter, to prevent clogging or fouling. A method for filtering a flow of fluid comprises directing a flow of fluid generally parallel to the surface of a filter to prevent clogging or fouling of the filter. A method for filtering a flow of fluid is also disclosed, comprising vibrating a filter by applying a flow of fluid to the filter.

The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and / or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.

A cross-flow filtration apparatus is provided. The cross-flow filter is a spiral wound filter that includes a semi-permeable membrane wrapped around a perforated central tube. The semi-permeable membrane includes a feed spacer and a membrane. The feed spacer is a biocidal feed spacer with a biocidal agent impregnated within the feed spacer to prevent biofouling of the feed spacer and the membrane.

The invention relates to a litchi fruit vinegar beverage and a production method thereof. The production method comprises the following steps of: removing shells and kernels of fresh litchis, and crushing the pulp to squeeze a juice; defecating the juice at a low temperature; separating the litchi juice; adding lactic acid bacteria into the litchi juice to perform fermentation for the first time; performing cross flow filtration to remove the lactic acid bacteria, and adding wine yeast into the litchi juice to perform fermentation for the second time; adding acetic acid bacteria into the litchi juice to perform fermentation for the third time to obtain a litchi raw vinegar; mixing the raw vinegar with a fruit juice, fructo-oligose (prebiotics), honey, purified water and the like in certain proportion; and filtering the mixture through an ultrafiltration membrane and performing aseptic canning to obtain the litchi fermented vinegar beverage. The litchi fruit vinegar beverage has a unique production process, and after multi-bacteria, low-temperature and long-time fermentations, the produced vinegar beverage has strong litchi fruit aroma and thick mouthfeel integrates nutritional and health-care functions, and is a novel nutritious, cosmetic and pollution-free green beverage.

The present invention relates to a mobile water purification system employing crossflow filtration, such as reverse osmosis filtration. One embodiment of the invention discloses a mobile water purification system comprising a housing, a pump unit and a piping system for providing fluid communication between a water inlet, a pre-filtration unit, a crossflow filtration unit, a disinfection unit and an outlet for supply of purified water, wherein the pre-filtration unit comprises sediment / cartridge filtrations means and dechlorination means, the cross-flow filtration unit comprises a plurality of parallel and / or sequentially arranged membrane filters, and the piping system is reconfigurable such that the crossflow filtration unit can be bypassed. The present water purification system is adapted to be deployed in remote areas substantially anywhere in the world.

A membrane filter process for refining saline includes such steps as dissolving salt to obtain saturated solution, adding sodium hydroxide, sodium carbonate and barium chloride, reaction to generate magnesium hydroxide, calcium carbonate and barium sulfate, adding coagulating precipitant and oxidant for pre-treating, adsorbing and depositing to remove magnesium hydroxide colloid and part of particles, cross-flow filtering by inorganic membrane, and ion exchange.

The invention relates to a method for measuring concentration of low-concentration soluble organic nitrogen in water, in which the nano filtration membrane separation technology is employed to accurately measure concentration of soluble organic nitrogen. In the preparation process before pretreatment, membrane with a pore diameter being more than or equal to 0.22mu m and less than or equal to 0.45mu m is employed to remove particle impurities of a water sample.300-500mL of filtered water sample is taken, pH value is adjusted to 6.0-9.0; in the process of pretreatment, selective nano filtration membrane with a cut-off molecular weight being 150-500 Dalton is adopted for dead-end or cross flow filtration; so that 6-15 times of concentration and enrichment of DON in the water sample can be achieved; the DON content is obtained by using the total nitrogen to reduce other forms of nitrogen content of other measurements and then dividing actual concentration times. In the invention, accuracy and precision of DON measurement are greatly improved, so that the problems that negative values often appear in the direct water sample determination method and concentration standard deviation is large are solved; in addition, the whole measurement process of the measurement method is simple and effective, easy to operate, low in cost, so that the measurement method can be widely applied to surface water and ground watermonitoring and monitoring and analysis of small, medium and large waterplants.

A fan for a cross flow fan assembly, including a plurality of elongate fan blades supported in an axial cylindrical pattern about a rotational axis by disk shape fan blade mounting members located adjacent ends of the blades. The fan blades have radial outer end portions defining an outer diameter of the fan, radial inner end portions opposite the radial outer end portions, and curved intermediate portions between the radial outer end portions and the radial inner end portions, respectively. Each of the fan blades is oriented such that the radial outer end is at about a 28° angle to a line tangent to the fan diameter at the outer end portion thereof, and the radial inner end portion is directed radially inwardly directly toward the axis or such that a line tangential to the radial inner end portion will pass through the axis.

A fluid filtration system comprising a cross-flow filter is arranged to permit a first pump to recirculate part of the retentate of the filter to the inlet of the cross-flow filter and a second pump to return part of the permeate to the inlet of the cross-flow filter. A third pump is configured supply source fluid to the inlet of the filter. The flow path between the second pump and the cross-flow filter inlet may include an adsorption filter that may selectively remove contaminants, toxins, or pathogens in the permeate. A controller may control the first, second and third pumps to provide predetermined flow ratios among the fluid flow paths of the system in order to achieve a desired filtration level. This system may be applicable to the removal of harmful substances from blood, by first separating the plasma from the blood and then removing harmful substances from the plasma.

The present invention includes a system and method for transferring a selected solute species from a fluid mixture to a fluid media. The system of the present invention includes a convergent channel for passing a fluid mixture containing a selected species tangentially across the first surface of a porous membrane. A fluid media is directed to flow tangentially over the second surface of the membrane. As the fluid mixture and the fluid media flow on opposite sides of the membrane, the selected species traverses the membrane leaving the fluid mixture and entering the fluid media. The volumetric loss to the fluid mixture associated with the loss of the selected species is compensated for by the convergency of the channel. As a result a constant velocity is maintained over the membrane, maximizing the selectivity of the filtration process.

Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, clostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, clostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and / or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.

Multivesicular liposomes are prepared at commercial scales by combining a first w / o emulsion with a second aqueous solution to form a w / o / w emulsion using a static mixer. Solvent is removed from the resulting emulsion to form multivesicular liposome-containing compositions. Further optional process steps include primary filtration and secondary cross-flow filtration. The products produced according to the processes of the invention can be produced through a series of aseptic steps.

A micro-filter membrane made of hollow polyolefin fibers and with permanent hydrophilicity is prepared from the ordinary basic membrane of hollow polyolefin fibers through immersing in alcohol or surfactant, filtering aldehyde solution and filming liquid containing PVA and / or polyethandiol or polyvinyl pyrrolidone, cross-linking reaction, immersing in deionized water and drying.

The present invention provides a method and apparatus for purifying effluent wastewater utilizing electrophoretic cross-flow filtration and electrode ionization. The method first comprises filtering the water in a cross-flow direction with a filter membrane in the presence of an electric field that is operative to drive suspended particles away from a surface of the filter membrane. The permeate containing dissolved solids is next passed through a mixture of at least one cation-exchange resin and at least one anion-exchange resin disposed between a cation-selective membrane and an anion-selective membrane in the presence of an electric field. The electric field drives cations in the permeate through the cation-selective membrane, and drives anions in the permeate through the anion-selective membrane, thereby to form deionized water. The apparatus includes cell modules adapted to be used in plate-and-frame or radial flow configurations.

A crossflow filtration system including at least one quick dry change crossflow filtration cartridge designed to rotatably interface with a manifold assembly. The quick dry change crossflow filtration cartridge can comprise a membrane element, for example an ultrafiltration membrane, microfiltration membrane, nanofiltration membrane or high-flux reverse osmosis membrane element enclosed within a housing. The quick dry change cartridge includes an inlet stream, a permeate stream and a concentrate stream. The manifold assembly includes three similar flow paths; an inlet stream, a permeate stream and a concentrate stream. When engaged, the cartridge and manifold assembly define continuous inlet flow paths, permeate flow paths and concentrate flow paths that connect across the interface. Thus, all of the connections to the water filtration system can be made onto the manifold, and the resulting connected system is compact and easy to connect.