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51 results about "Membrane rupturing" patented technology

Membrane rupture device special for obstetrical delivery room

ActiveCN223473844UObstetrical instrumentsDelivery roomsObstetrical delivery
The utility model discloses a special membrane rupturing device for an obstetrical delivery room, which is applied to the technical field of membrane rupturing devices and is characterized in that a fixed cylinder extends into the vagina of a pregnant woman, a protective sleeve is attached to a fetal membrane, then thrust is continuously applied to the fixed cylinder, the protective sleeve and a first spring are compressed at the moment, and a membrane rupturing needle slowly extends out of a through hole and punctures the fetal membrane; when the length of the membrane rupturing device needs to be adjusted, limitation on the telescopic rod is relieved through the fixing mechanism, then the handheld part is pulled to drive the telescopic rod to move, and the telescopic rod is fixed through automatic reset of the fixing mechanism.
Owner:HAIKOU PEOPLES HOSPITAL

Device and method for measuring membrane rupture pressure of high-pressure gas

The invention provides a high-pressure gas membrane rupture pressure measuring device and a measuring method thereof, and belongs to the technical field of pressure measurement. The measuring device comprises a pressure generation system, a gas compression system, a gas injection system, a pressure measuring system and a diaphragm clamping system. The piston divides the cavity into a hydraulic cavity and a gas compression cavity, and the piston is hydraulically driven to compress the pre-filled gas, so that the diaphragm is broken. The pressure measurement system records pressure-time data in real time, and a sliding window average algorithm is adopted to extract a membrane rupture pressure peak value. According to the technical scheme, inert gas is used, initiating explosive devices are not used, membrane rupture energy is only gas expansion, the protection box can absorb fragments, and explosion-proof transformation is not needed in a laboratory. And the smoothed unique membrane rupture pressure value is output through a sliding window averaging algorithm, and manual reading errors are eliminated. According to the technical scheme, the device is compact in structure, safe to operate, rapid in testing and suitable for accurately measuring the diaphragm rupture pressure of the gas gun diaphragm in a conventional laboratory.
Owner:BEIJING INST OF SPACECRAFT ENVIRONMENT ENG

Ultrafiltration membrane pressure detection device

The utility model provides an ultrafiltration membrane pressure detection device, which relates to the technical field of ultrafiltration membrane pressure detection, and comprises a shell, the top of the shell is provided with a top cover, the top of the top cover is connected with a drain outlet, the front surface of the shell is connected with a monitoring alarm assembly, and the monitoring alarm assembly comprises a purified water outlet. According to the utility model, the pressure sensor and the flow sensor are respectively arranged at the purified water outlet and the drain outlet, so that a real-time monitoring effect can be achieved, and when the flow or the pressure difference reaches a set numerical value, the PLC controller gives an instruction to carry out systematic backwashing, forward flushing and other maintenance actions on the membrane at the moment; and if the trans-membrane pressure difference almost does not exist, the serious problems such as membrane breakage are possibly caused, and the alarm can automatically give an alarm to remind an operator to check the fault of the membrane in time, so that the problem that the membrane cannot be normally used due to blockage is avoided.
Owner:HUNAN JINGXIANG ENVIRONMENTAL PROTECTION TECH CO LTD

Biodegradable film punching and collecting device

ActiveCN224196913UAvoid difficult collectionavoid pullingMetal working apparatusAir pumpMechanics
The utility model discloses a biodegradable film punching and collecting device, which comprises a punching unit, which comprises a rotating shaft, a punching wheel rotatably arranged on the rotating shaft, an armrest frame arranged between the two ends of the rotating shaft, and punchers arranged on the punching wheel at intervals along the circumferential direction, and each puncher is provided with a film breaking opening; the film collecting unit comprises an air nozzle installed in the film breaking opening, an air pump installed on the punching wheel, an air pipe connected with the air pump and the air nozzle and a film collecting box installed on the lower middle portion of the rear side of the punching wheel, and a film collecting opening is formed in the side, facing the punching wheel, of the film collecting box. Through the arranged film collecting unit, when a tapper rotating to the bottom breaks a film, an air pump sucks air, so that broken residual films are sucked into a film breaking opening, when the tapper rotating to the bottom rotates to a film collecting box, the air pump blows air, so that the residual films in the film breaking opening are blown into the film collecting box to be stored, the situation that the residual films are difficult to collect is avoided, and the aesthetic feeling is improved; and the recycling of resources is realized.
Owner:BIJIE COMPANY OF GUIZHOU TOBACCO

Artificial membrane rupture structure

The invention relates to the technical field of medical tools, in particular to an artificial membrane rupturing structure which comprises a barrel and a suction cup mounted at the top end of the barrel and further comprises a guide seat, a membrane rupturing device, a membrane rupturing device and a membrane rupturing device, the guide seat is mounted in the barrel, and a through hole is formed in the guide seat; the adsorption mechanism is installed in the cylinder body and connected with the guide seat, and the adsorption mechanism enables the suction cup to be adsorbed to the surface of the amniotic membrane; the artificial membrane rupturing structure is different from the prior art, in the using process of medical staff, the amniotic membrane can be clamped and fixed only by attaching the suction cup to the amniotic membrane and then pulling the hollow push rod, then puncturing is automatically conducted, the flow speed after membrane rupturing is stable, the membrane rupturing can be easily completed even though the medical staff with less experience, and operation is easy; the amniotic fluid after rupture of the membrane automatically flows to the outside through the drainage tube from the inside of the cylinder, and the amniotic fluid is not in contact with the uterus of the pregnant woman, so that the probability of infection in the uterus of the pregnant woman is greatly reduced, and the turbidity of the amniotic fluid flowing out can be directly observed.
Owner:JINPEN TOWNSHIP HEALTH CENTER ZHONGSHAN DISTRICT LIUPANSHUI CITY (JINPEN TOWNSHIP MATERNAL & CHILD HEALTH & FAMILY PLANNING SERVICE CENTER ZHONGSHAN DISTRICT LIUPANSHUI CITY)

Membrane rupture detection device

The utility model discloses a membrane rupture detection device, and belongs to the technical field of corona treatment. The broken film detection device comprises a rack, a detection mechanism, a driving mechanism, a corona mechanism and the like. Wherein the rack comprises a top plate and a bottom plate, at least four supporting columns are arranged between the top plate and the bottom plate, and at least two groups of supporting columns are formed; supporting rollers are arranged on the group of supporting columns; a winding roller is arranged on the other group of supporting columns; a detection mechanism is arranged on the rack; a corona mechanism is arranged between the supporting roller and the wind-up roller, and the corona mechanism is arranged on the side, close to the wind-up roller, of the detection mechanism; the rack is also provided with a driving mechanism, and one end of the driving mechanism is connected with the corona mechanism. Compared with the prior art, the possibility that the corona mechanism is damaged by the film is reduced, so that the production efficiency of the film is improved to a certain extent.
Owner:HONGTA PLASTIC CHENGDU CO LTD

In-situ windowing and membrane breaking device for covered stent

The utility model provides an in-situ windowing membrane rupture device for a covered stent, which relates to the field of medical instruments and comprises an outer tube, a middle-layer positioning tube, an inner-layer positioning tube and a membrane rupture guide wire which are sequentially sleeved from outside to inside and can relatively axially slide two by two, an elastic expansion part is connected to the peripheral surface of the far-end section of the middle-layer positioning tube and has an expansion state of expanding in the radial direction to be spherical and a contraction state of contracting in the radial direction; the outer tube can axially slide relative to the middle-layer positioning tube, so that the elastic expansion part is accommodated or released in the outer tube; the far-end face of the inner-layer positioning pipe is provided with concave-convex positioning sawteeth facing the far-end direction. The aorta covered stent at least relieves the technical problem that in the prior art, when an aorta covered stent is subjected to in-situ windowing and membrane rupture, guide wire positioning is not accurate.
Owner:BEIJING PERCUTEK THERAPEUTICS CO LTD

Safe membrane rupturing device for obstetrical department

The utility model is applicable to the field of medical instruments, and provides a safe membrane rupture device for obstetrics, which comprises a barrel, a plurality of vent holes are arranged at the upper end of the barrel, a threaded rod is in threaded connection with the upper end of the barrel, an I-shaped ring is fixedly connected with the lower end of the threaded rod, and the I-shaped ring is rotatably connected with a connecting frame. The lower end of the connecting frame is fixedly connected with an abutting plate. A lower bottom plate is slidably connected to the inner wall of the barrel, a membrane rupture needle is fixedly connected to the lower end of the lower bottom plate and used for puncturing amniotic fluid, a middle column is fixedly connected to the upper end of the lower bottom plate, an upper bottom plate is fixedly connected to the upper end of the middle column, and a resistance assembly is arranged on the upper bottom plate in a matched mode. A plurality of symmetrical first vent grooves are formed in the lower bottom plate, a plurality of symmetrical second vent grooves are formed in the middle column, and a plurality of symmetrical third vent grooves are formed in the upper bottom plate. The amniotic fluid puncturing device has the advantages that the amniotic fluid puncturing depth is controllable, and the amniotic fluid is effectively sucked away.
Owner:WUHAN UNIV OF SCI & TECH

Preserving fluid for improving stability of external vesicles as well as preparation method and application of preserving fluid

The invention relates to the technical field of protection of external vesicles, in particular to a preserving fluid for improving the stability of the external vesicles and a preparation method and application of the preserving fluid. The invention provides a preserving fluid for improving stability of external vesicles. The preserving fluid comprises an acidic buffer solution and a stabilizer, the acidic buffer solution is a citric acid buffer solution, and the stabilizer is cyclodextrin or a functionalized derivative thereof; and the pH value of the preservation solution is 6.0-7.0. The preserving fluid provided by the invention can stably store the external vesicles under the condition of low temperature (4 DEG C and-80 DEG C), and can effectively inhibit damage, such as membrane rupture and protein inactivation, of the external vesicles in the low-temperature storage process.
Owner:XIANGHU LABORATORY

Capsule polisher used after cataract surgery

The utility model relates to a capsular membrane polisher after cataract surgery, which comprises a connecting tube, a polishing head is rotatably connected to one end of the connecting tube far away from the connecting tube, a water outlet hole is arranged on the polishing head, the connecting tube is communicated with the water outlet hole, an impeller is arranged at the position of a tube opening where the connecting tube is connected with the polishing head, and the impeller is connected with the polishing head. A connecting rod is fixedly connected to the center of the impeller, the two ends of the connecting rod are rotationally connected with the side wall of the connecting pipe and fixedly connected with the side wall of the polishing head respectively, a pushing and injecting assembly is installed at the end, away from the polishing head, of the connecting pipe and used for injecting liquid into the water outlet hole, and the liquid drives the impeller to rotate when passing through the impeller. The capsular membrane polisher used after the cataract surgery aims to solve the problems that in the prior art, the head of a capsular membrane polisher is fixedly connected with a handle of the capsular membrane polisher, the polisher polishes the capsular membrane excessively due to excessive force in the using process, the safety is not high, the head needs to be rotated manually by workers, and the operation difficulty is large.
Owner:田艳

Obstetric nursing membrane rupture assistive device with negative pressure balancing function

ActiveCN119837613BIncision instrumentsMedical devicesIntra-AmnioticExtra-amniotic
This invention relates to the field of obstetric nursing technology, and in particular to an obstetric nursing device for ruptured membranes with a negative pressure balancing function. The device includes an insertion tube, an endoscope fixedly mounted on the upper rear end of the insertion tube, and a membrane rupture assembly located at the rear end of the insertion tube. The membrane rupture assembly includes a baffle plate fixed to the rear end of the insertion tube, with multiple guide membrane holes inside the baffle plate. A blade groove is formed on the rear end face of the baffle plate, and a membrane rupture blade is movably mounted inside the blade groove. The baffle plate of this invention effectively blocks the fetus inside the amniotic sac, allowing the soft outer wall of the amniotic sac to enter the guide membrane holes, thus preventing damage to the fetus during membrane rupture. Simultaneously, the membrane rupture blade is located inside the insertion tube, ensuring that neither the fetus nor the mother is harmed during membrane rupture.
Owner:THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV

Testing system for generating squeeze flow to strengthen ammonia combustion equipment

The invention discloses a test system for generating squish flow to strengthen ammonia combustion equipment. The test system comprises a first volume bomb body, a second volume bomb body and a squish flow regulation and control unit, the squeeze flow regulation and control unit comprises a membrane breaking mechanism and a flow guide plate; the membrane breaking mechanism is used for controlling a membrane breaking threshold value through an ejector pin with an adjustable distance and a membrane, and puncturing the membrane through the ejector pin under the action of high-pressure airflow of the first shell accommodating body, so that the first shell accommodating body generates extrusion flow towards the second shell accommodating body; and the flow guide plate is used for adjusting the extrusion flow direction. The high-pressure airflow generated by pre-combustion of the first containing bomb body serves as a squish flow power source, controllable squish flow is generated to the second containing bomb body through the squish flow regulation and control unit, an ammonia gas combustion test is carried out in the second containing bomb body, the strengthening effect of the squish flow on ammonia combustion is quantified, and the device has the advantage of being high in controllability.
Owner:HANGZHOU WANXIANG POLYTECHNIC

Stable Pickering emulsion based on D-glucosamine-magnesium compound as well as preparation method and application of stable Pickering emulsion

The invention provides a stable Pickering emulsion based on a D-glucosamine-magnesium compound, a preparation method and application, and relates to the technical field of emulsion preparation. An emulsion system is stabilized through a D-glucosamine-magnesium compound, collaborative delivery of D-glucosamine and magnesium ions is completed, Mg < 2 + > and amino groups and hydroxyl groups of the D-glucosamine form weak coordinate bonds, Ostwald ripening and gravity settling in long-term storage are resisted, it is ensured that oil drops are uniform in size, and the shelf life is prolonged. Through weak coordinate bonds and response of pH response synthase, efficient release of targeted intestinal tracts is realized, and bioavailability is improved. Meanwhile, due to the large hydration radius of Mg < 2 + >, a thick hydration layer is formed on the surface of Mg < 2 + >, mechanical damage of ice crystals to an interfacial film is inhibited at low temperature, and film breakage caused by particle dehydration is slowed down at high temperature; coordination bonds in the D-glucosamine-magnesium compound are stably adsorbed at low temperature and moderately dissociated at high temperature without damaging the overall structure, so that the stable temperature range of the emulsion is further widened.
Owner:TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE

Membrane breaking forceps with splash guard

This utility model discloses a membrane rupture forceps with a splash guard, comprising a first forceps body, a second forceps body, and a shield. The first forceps body and the second forceps body are rotatably connected by a connecting device. The first forceps body includes a first handle and a first jaw and a first gripper located at both ends of the first handle. The second forceps body includes a second handle and a second jaw and a second gripper located at both ends of the second forceps body. One end of the shield is an open end, and the other end of the shield has a groove extending radially along the open end. The first jaw and the second jaw protrude from the open end through the groove. Sliding elements are provided on both the first handle and the second handle, and the first handle and the second handle are slidably connected within the groove along its length direction via the sliding elements. This utility model, by incorporating a splash guard, prevents amniotic fluid from splashing onto the faces and bodies of medical personnel, thus protecting their health.
Owner:THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV

A content extraction method based on cell membrane capacitance change

ActiveCN120992422Bavoid difficultiesReduce extraction volume is too lowElectric/magnetic area measurementsParticle size analysisCapacitanceCell membrane
The application provides a content extraction method based on cell membrane capacitance change, and belongs to the field of cell-level micromanipulation technology, and comprises the following steps: S1, a change relationship between cell membrane capacitance and cell membrane surface area is established; S2, a change relationship between cell membrane surface area and volume is approximately established; S3, high-resistance sealing and membrane rupture of cells are completed, constant voltage cell content extraction operation is performed, and cell membrane capacitance values in the extraction process are obtained in real time through capacitance fitting; S4, content extraction amount is estimated; S5, actual cytoplasm extraction amount is calculated based on a rotary L-shaped electrode, the relationship model established in S2 is corrected, and finally, quantitative extraction of cell contents is realized. The application utilizes an electrical model of cell membrane capacitance, realizes real-time feedback of cell content extraction amount, realizes quantitative control of content extraction, can realize a cytoplasm extraction success rate of 62.5% in the case of a whole cell patch clamp structure, and the average cytoplasm extraction amount control error is less than 6% of the total cell volume.
Owner:NANKAI UNIV

Membrane structure solvent for nanopore sequencing and preparation method and application thereof

PendingCN122303403AAvoid breakage and other situationsUnlimited flow statusNetwork structureOrganic chemistry
This application provides a membrane structure solvent for nanopore sequencing, its preparation method, and its application. The membrane structure solvent for nanopore sequencing has the membrane structure located within a crosslinkable solvent; the crosslinkable solvent self-crosslinks to form a network structure, encapsulating the membrane structure. This application crosslinks the solvent of the membrane-forming solution to form a network structure, thereby confining the formed membrane structure within this network structure and ensuring its stability, preventing membrane rupture and other issues.
Owner:BEIJING POLYSEQ BIOTECH CO LTD

A magnetic response chain micro-motor with peroxidase-like catalytic activity for membrane rupture and sterilization, and a preparation method and application thereof

PendingCN122644131ALiquid mediumPeroxidase
The application belongs to the technical field of micro-nano robots, and relates to a magnetic response chain micro motor with peroxidase-like catalytic activity for breaking a membrane and sterilization and a preparation method and application thereof. The application discloses a magnetic response chain micro motor with peroxidase-like catalytic activity for breaking a membrane and sterilization. Under the action of an applied magnetic field, the magnetic response chain micro motor can destroy the structure of a bacterial biofilm and kill bacteria in the bacterial biofilm in a weakly acidic to neutral liquid medium, and can be applied to antibiofilm.
Owner:ZHEJIANG UNIV OF TECH +1

Content extraction method based on cell membrane capacitance change

ActiveCN120992422AElectric/magnetic area measurementsParticle size analysisCapacitanceIntracellular
The invention provides a cell membrane capacitance change-based content extraction method, and belongs to the technical field of cell-level micromanipulation, and the method comprises the following steps: S1, establishing a change relationship between cell membrane capacitance and cell membrane surface area; s2, approximately establishing a change relation between the surface area and the volume of the cell membrane; s3, completing high-resistance sealing and membrane rupture of the cells, executing constant-pressure cell content extraction operation, and obtaining a cell membrane capacitance value in the extraction process in real time through capacitance fitting; s4, estimating the content extraction amount; and S5, calculating an actual cytoplasm extraction amount based on a rotating L-shaped electrode, correcting the relation model established in the step S2, and finally realizing quantitative extraction of the cell contents. According to the invention, the electrical model of the cell membrane capacitance is utilized to realize the real-time feedback of the extraction amount of the cell contents and the quantitative control of the extraction of the contents, the cytoplasm extraction success rate of 62.5% can be realized under the condition that a whole-cell-membrane clamp structure is formed, and the control error of the average cytoplasm extraction amount is less than 6% of the total volume of the cells.
Owner:NANKAI UNIV

PH-sensitive membrane rupture sequence polypeptide and application thereof

The invention provides a pH-sensitive membrane rupture sequence polypeptide with a structure as shown in a formula (I), or a stereoisomer or pharmaceutically acceptable salt thereof, and application of the pH-sensitive membrane rupture sequence polypeptide or the stereoisomer or the pharmaceutically acceptable salt thereof. The macromolecular material is hydrophobic and electrically neutral under normal physiological pH, can be self-assembled into nano-particles, is compact in assembly, and has weak interaction with cell membranes; under the condition of slightly acidic pH, the amphiphilic polymer can be protonated to form an amphiphilic structure consisting of a hydrophobic structural domain and a cationic structural domain, has strong interaction with cell membranes and has strong membrane rupture activity, so that the amphiphilic polymer can efficiently and highly selectively kill tumor cells.
Owner:SOUTH CHINA UNIV OF TECH +1

A pure water machine and a method for testing a desalination rate of an RO membrane to determine whether the membrane is damaged

A water purifier includes a composite filter, an RO filter, and a post-filter. A booster pump, an inlet solenoid valve, and a raw water TDS sensor are installed on the pipeline between the outlet of the composite filter and the inlet of the RO filter. A pure water TDS sensor is installed on the pipeline between the RO filter and the post-filter. The water purifier also includes a detection and desalination rate calculation module and an alarm. The detection and desalination rate calculation module calculates the desalination rate based on the measured TDS values ​​of the raw water and pure water, and determines whether the RO membrane is damaged based on two consecutive desalination rate readings. This invention has a reasonable structure, a simple and accurate membrane rupture detection method, and can promptly detect the RO membrane to ensure drinking water safety.
Owner:ZHEJIANG RUNXIN ELECTRIC APPLIANCE CO LTD

Dialyzer membrane rupture detection device and control method

The invention discloses a dialyzer membrane rupture detection device and a control method, which are used for detecting a dialysis membrane when a user performs dialysis, and comprise a dialysate supply module, a pre-penetration pump, a balance cavity, a post-penetration pump, an electromagnetic valve group, a first pressure sensor, a dialyzer connection module and a control module, the dialyzer connecting module is provided with a liquid supply port and a liquid return port; dialysate is connected with a dialyzer through a dialysate supply module, a pre-penetration pump, a balance cavity, an electromagnetic valve group and a dialyzer connecting module, so that the dialyzer flows back to a post-penetration pump through the electromagnetic valve group and is discharged; the opening and closing of the electromagnetic valve group can be controlled by the control module according to a preset program, so that pre-filling and sealing detection can be realized, and an automatic and closed-loop membrane rupture test can be completed. Compared with a manual visual method or a simple leak detection method, the method has the advantages that the detection accuracy and repeatability are improved, manual operation errors are reduced, recording and tracing are facilitated, and the clinical use safety and working efficiency are improved.
Owner:GUANGZHOU SINOKANG MEDICAL EQUIP CO LTD

Anti-outflow membrane rupture device for obstetrics and gynecology department

The invention provides an anti-outflow membrane rupture device for the obstetrics and gynecology department, and relates to the technical field of membrane rupture devices. The anti-outflow type membrane rupture device for the obstetrics and gynecology department comprises a puncture device, a limiting device, a protection device and a sealing device, the puncture device is arranged on the inner side wall of the limiting device in a sliding mode, the protection device is arranged at the front end of the limiting device, the sealing device is arranged at the front end of the protection device, and the puncture device comprises a sliding rod; a puncture head is fixedly connected to the front end of the sliding rod, a flow guide groove is formed in the side wall of the puncture head, a membrane rupture hook is rotationally connected to the front side of the inner side wall of the flow guide groove, and a soluble clamping strip is fixedly connected to the upper position of the front end of the inner side wall of the flow guide groove. By arranging the puncture device, a patient is prevented from being injured, safety and reliability are further improved, by arranging the limiting device and the protection device, the equipment can be disinfected, the infection risk is effectively reduced, and by arranging the sealing device, the equipment is effectively prevented from being polluted by the outside before being used.
Owner:姜新华

Reaction system for realizing oil-water separation by coupling electrostatic field with microchannel and suitable for continuous treatment of oil-containing sewage in oil field

The invention also discloses a reaction system for realizing oil-water separation by coupling the electrostatic field with the micro-channel, which is suitable for continuous treatment of oil-containing sewage in an oil field. The reaction system comprises the micro-channel reactor unit and the electrostatic field coupling unit. The micro-channel atomization pretreatment releases more activation sites, the space and time of an electrostatic field are synchronously coupled, and the integrated tube body electrode and the automatic power regulation are synergistically acted on the membrane rupture, polarization and coalescence process of emulsified oil drops; therefore, under the continuous operation condition, the obvious beneficial effects that the demulsification rate is reduced from the minute level to the second level, the energy consumption is reduced by more than 80% compared with the traditional process, the emulsified oil is quickly demulsified, and the equipment is not blocked for a long time are realized.
Owner:NORTHEAST GASOLINEEUM UNIV

Membrane rupture and amniotic fluid collection device utilizing negative pressure adsorption rotary cutting

ActiveCN223695975UIncision instrumentsObstetrical instrumentsFoetal membranesSurgery
The utility model discloses a membrane rupture and amniotic fluid collection device utilizing negative pressure adsorption and rotary cutting. The membrane rupture and amniotic fluid collection device comprises an adsorber, a rotary cutting device and a vacuum generating device, the adsorber is tubular, the two ends of the adsorber are an adsorption end and an operation end respectively, a one-way membrane and a sealing cover are arranged in the adsorber, the one-way membrane is fixed to the inner wall of the adsorber, an amniotic fluid cavity is formed between the one-way membrane and an end opening of the adsorption end of the adsorber, and a negative pressure cavity is formed between the sealing cover and the one-way membrane. An operation cavity is formed between the sealing cover and the port of the operation end of the adsorber; the rotary cutting device comprises a rotary handle and a rotary cutting blade; the vacuum generating device comprises a negative pressure suction pipe and a negative pressure device. According to the utility model, the rotary cutter with the flower-shaped rotary cutting edge is used for replacing a needle, so that the fetal membrane can be broken after a fetus is separated from the fetal membrane, and the fetus is prevented from being accidentally injured. In the membrane rupturing process, micro-feeding of the tool bit can be achieved, the safety of a fetus is further guaranteed, the force and depth of the fetal membrane pulled into the device can be accurately controlled, and the membrane is ruptured accurately.
Owner:YUYAO PEOPLES HOSPITAL

A solvent carrier for nanopore sequencing and methods of making and using the same

PendingCN122303402AEnd-groupNetwork structure
This application provides a solvent carrier for nanopore sequencing, its preparation method, and its application. The solvent carrier for nanopore sequencing comprises a nanopore sequencing unit containing microwells, the upper end of which is covered with a nonpolar film-forming solution. The nonpolar film-forming solution includes a copolymer membrane and a nonpolar solvent. The end groups of the nonpolar solvent contain unsaturated bonds I, and the surface of the upper end of the microwell contains unsaturated bonds II. The nonpolar solvent is cross-linked with the surface of the upper end of the microwell to form the solvent carrier. This application cross-links the solvent of the film-forming solution to form a network structure, thereby allowing the formed membrane structure to be confined within this network structure and to exist stably, avoiding membrane rupture and other issues.
Owner:BEIJING POLYSEQ BIOTECH CO LTD

Preparation and application of oncolytic virus specifically promoting tumor cytoplasmic membrane rupture

PendingCN122357462ATherapeutic effectCytoplasm
This invention relates to the preparation and application of an oncolytic virus that specifically promotes the rupture of tumor cell plasma membranes. Specifically, this invention utilizes a glioblastoma-specific Nestin enhancer or a tumor cell-specific Survivin promoter to drive the specific expression of the NINJ1 or DTA gene, thereby enhancing the lytic and killing ability of cells. The oncolytic virus G005 expressing NINJ1 exhibits strong killing ability against tumor cells, and the tumor completely disappears in an orthotopic glioma animal model. It can also rapidly restore the weight loss in mice caused by tumor burden, demonstrating that the oncolytic virus G005 has excellent therapeutic effects against GBM.
Owner:JINAN UNIVERSITY

Transient load loading test device and method for simulating impact load effect on battery

The invention discloses a transient load loading test device and method for simulating the impact load effect on a battery, and the device is characterized in that a high-pressure section is sequentially provided with a membrane rupture section, a first low-pressure section, an observation cabin, a second low-pressure section, a third low-pressure section, a vacuum / loading cabin, and a recovery cabin in the axis direction; diaphragm mounting structures are arranged between the high-pressure section and the diaphragm breaking section as well as between the diaphragm breaking section and the first low-pressure section and are used for mounting a diaphragm and simulating an impact pressure load by using pressure generated when the diaphragm is broken, and the target to be tested is arranged on the second low-pressure section. And the response condition of the battery subjected to the similar impact characteristic load effect in the actual environment can be accurately reflected.
Owner:BEIJING INST OF TECH

Obstetric artificial rupture of membranes needle

The utility model provides a kind of obstetric artificial membrane rupture needle, it is related to obstetric technology field, including: barrel, barrel inside is equipped with storage groove, barrel inside is equipped with moving groove, needle head is equipped in storage groove, connecting rod is equipped in moving groove;Limiting component is set between barrel and connecting rod, limiting component includes: limiting slot, limit hole and limiting rod;And setting between needle head and connecting rod is fixed component, fixed component includes: moving plate, connecting block, clamping groove, mounting block and elastic sheet.This kind of can be limited to the distance of needle head by the setting of limiting component, avoid needle head to cause harm to maternal and fetus, simultaneously in the process of needle head extension whole in storage groove, avoid needle head to scratch inside cervix, by the setting of fixed component, can according to the actual situation of maternal and fetus, quickly clamped suitable needle head carries out membrane rupture operation.
Owner:WUHAN CHILDRENS HOSPITAL

Membrane separation assembly self-adaptive pressure stabilizing system based on pressure difference feedback

The utility model belongs to the technical field of membrane separation equipment, particularly relates to a self-adaptive pressure stabilizing system of a membrane separation component based on pressure difference feedback, and aims to solve the problem that the pressure is controlled only by the frequency of a fixed valve or pump when the existing system is actually used, and the pressure cannot be controlled when the resistance of the membrane component is changed due to pollution and the like. According to the technical scheme, the membrane separation assembly self-adaptive pressure stabilizing system based on pressure difference feedback comprises a membrane separation assembly body, and the two ends of the membrane separation assembly body are provided with a liquid inlet end and a liquid outlet end respectively; the utility model has the beneficial effects that the integrated controller accurately regulates and controls according to the preset pressure, sends instructions to the variable frequency pump and the electromagnetic valve, maintains the pressure stable, greatly improves the separation efficiency, and reduces the risks of membrane rupture and leakage. The filter screen at the liquid inlet end intercepts impurities, slows down membrane pollution, prolongs the service life of a membrane assembly, guarantees normal operation of other parts, and reduces equipment faults.
Owner:CHONGQING BUSINESS VOCATIONAL COLLEGE

Membrane puncturing device for obstetrics and gynecology department

The utility model relates to the technical field of medical instruments, in particular to a fetal membrane puncturing device for gynaecology and obstetrics, which comprises a connecting handle, the front end of the connecting handle is rotatably connected with a rotating handle, a pushing rod is arranged in the connecting handle in a sliding and penetrating mode, one end of the pushing rod extends into the rotating handle, and an external thread is arranged on the surface of the end portion of the pushing rod. And an internal thread matched with the rotating handle is arranged in the rotating handle. By adding a thread matching mechanism of the rotating handle and the pushing rod, accurate control over the feeding amount and the puncturing depth of the membrane rupturing needle is achieved, the risk caused by too deep puncturing to a fetus is reduced, the stability and accuracy of operation are remarkably improved, the uncertainty caused by manual operation is reduced, and therefore the safety of the membrane rupturing process is improved.
Owner:SHENZHEN KUNPENG MEDICAL TECH CO LTD