38 results about "Fetal membrane" patented technology

The utility model discloses a special membrane rupturing device for an obstetrical delivery room, which is applied to the technical field of membrane rupturing devices and is characterized in that a fixed cylinder extends into the vagina of a pregnant woman, a protective sleeve is attached to a fetal membrane, then thrust is continuously applied to the fixed cylinder, the protective sleeve and a first spring are compressed at the moment, and a membrane rupturing needle slowly extends out of a through hole and punctures the fetal membrane; when the length of the membrane rupturing device needs to be adjusted, limitation on the telescopic rod is relieved through the fixing mechanism, then the handheld part is pulled to drive the telescopic rod to move, and the telescopic rod is fixed through automatic reset of the fixing mechanism.

The invention discloses a gynaecology and obstetrics intelligent visual midwifery system based on an ultrasonic technology, and relates to the technical field of ultrasonic midwifery, the system constructs a two-dimensional coordinate system and extracts ultrasonic echo total time and respiratory phase data, and fetal membrane structure data and fetal physiological data are generated through dimensionless processing and data analysis. And constructing an amniotic sac thickness gradient index dyn according to the thickness gradient change to evaluate the structural stability of the amniotic sac. And if the fetal respiratory phase drift index psh is evaluated to be unstable, calculating the fetal respiratory phase drift index psh, and jointly constructing a comprehensive parturition risk index Rco with the amniotic sac thickness gradient index dyn to reflect the potential parturition risk of coupling of the fetal stress level and the membrane structure variation. And the system generates different types of intervention instructions according to the evaluation result of the comprehensive parturition risk index Rco. Multi-dimensional data mapping and layer display are achieved, linkage display of a risk thermodynamic diagram and a breathing phase curve is supported, and a visual and traceable dynamic midwifery decision basis is provided for medical staff.

The invention discloses a premature rupture of fetal membranes detection kit for gynaecology and obstetrics, and particularly relates to the field of detection kits, the premature rupture of fetal membranes detection kit comprises a kit body and a collector, a partition plate and a buckle cover are arranged in the kit body, the buckle cover is located above the partition plate, and a refrigerating chamber is arranged between the partition plate and the buckle cover; a test tube is placed in the refrigerating chamber, the test tube is used for containing a dissolving solution, a plurality of extrusion protrusions are fixedly arranged in the test tube, the extrusion protrusions are arranged at equal intervals, and the extrusion protrusions are all located in the dissolving solution; a collecting end is arranged at the end part of the collector, and extrusion areas are arranged among the plurality of extrusion bulges. By arranging the extrusion bulge in the test tube, when the collection end vertically moves back and forth in the test tube, the extrusion bulge extrudes the collection end and cooperates with the collection end to stir a dissolving solution, so that a sample and the dissolving solution are fully mixed, residues of the sample on the collection end are reduced, the sample is fully released, and the mixing efficiency is improved; and the accuracy of a detection result is ensured.

The present invention relates to the field of medical devices, and in particular to an amniotic fluid detection pad for premature rupture of membranes, comprising a pad body, wherein a water absorption layer, a dilution layer and an internal standard layer are sequentially arranged in the pad body from top to bottom; a first hollow cavity is arranged inside the dilution layer, a diluent is arranged in the first hollow cavity, a first isolation layer is detachably attached to the upper end of the first hollow cavity, and a second isolation layer is detachably attached to the lower end; a second hollow cavity is arranged inside the internal standard layer, and an internal standard liquid is arranged in the second hollow cavity; the first isolation layer is used to isolate the water absorption layer and the first hollow cavity, and the second isolation layer is used to isolate the first hollow cavity and the second hollow cavity. The present application can filter and collect liquid leaked by pregnant women in the late pregnancy, pretreat the subject's amniotic fluid with the diluent, and extract the diluted amniotic fluid with the internal standard liquid, thereby ensuring the purity of the extracted amniotic fluid and improving the accuracy of detection.

The present invention provides a novel composition of platelet rich fibrin and platelet rich plasma for sealing amniotic fluid leak in premature rupture of amniotic membranes (PROM) in pregnant women. The present invention further provides a method to prepare said composition.

The utility model discloses a tire membrane frame which comprises a base, two arc-shaped plates, two end plates and a plurality of membrane frame plates. The two arc-shaped plates are oppositely arranged, the base is used for fixing and supporting the arc-shaped plates, and the two ends of the multiple membrane frame plates are fixed between the two arc-shaped plates respectively; the base comprises two vertical hollow pipes, and the two hollow pipes are fixedly arranged on the outer side face of the arc-shaped plate and located in the middle of the arc-shaped plate in the length direction. The end plates are fixedly connected with the ends, in the length direction, of the two arc-shaped plates correspondingly, and the length direction of the end plates is larger than the width direction of the two arc-shaped plates, so that the two length ends of the end plates extend out of the arc-shaped plates. Supporting plates located outside the arc-shaped plates are fixed to the two ends of the end plates correspondingly. At least one hollow pipe is provided with a hanging device for hanging an arc-shaped steel bar, and the hanging device and the supporting plate jointly support the arc-shaped steel bar. Raw materials and arc-shaped steel bars of the forming die frame are placed, the working process is standardized, and the frequency of taking and placing the arc-shaped steel bars by an operator is reduced.

A system includes a processor configured for communication with an ultrasound probe, where the processor is configured to: control the ultrasound probe to obtain a plurality of ultrasound image frames during a blind sweep protocol on a patient with a pregnancy; provide the plurality of ultrasound image frames as an input to a deep learning network trained to detect at least one of maternal anatomy or fetal anatomy; and generate, as an output of the deep learning network, a detection. The detection includes at least one of an inter-twin membrane within the plurality of ultrasound image frames, or a plurality of fetal anatomical parts within the plurality of ultrasound image frames. The processor is further configured to determine, using the detection, whether the pregnancy comprises a multiple gestation; and provide, to a display in communication with the processor, an output representative of the determination.

The present invention relates to functionally improved epithelial stem cells. The epithelial stem cells with improved functionality by a method of the present invention are prepared without genetic modification, thus being less likely to cause side effects due to DNA delivery / modification, are derived from the amniotic membrane in which no tissue-compatible antigen (factor) is expressed, thus having no rejection, and exhibit improved cell migration and would healing effects due to the improved functionality. Therefore, the epithelial stem cells can be used for the regeneration of various tissues, including the cornea, amniotic membrane, skin, and the like, and particularly can be used for the prevention or treatment of premature rupture of the amniotic membrane.

The utility model aims to provide a prefabricated foundation forming die structure which comprises a template main body and a fixing seat, buckles are arranged at four corners of the template main body, a positioning rod is arranged between two buckles on each side for connection, an anchor rod is inserted in the fixing seat, a fixing assembly is further arranged in the fixing seat, the fixing assembly comprises a clamping block, a supporting rod, an inserting plate and a spring, and the clamping block is connected with the supporting rod. A first sliding groove and a second sliding groove are formed in the fixing base, two notches are formed in the positioning rod, the size of the spliced two notches is the same as that of the inserting plate, the inserting plate is slidably installed in the first sliding groove, the clamping block is installed in the second sliding groove in a clamped and embedded mode, one side of the clamping block is an inclined face, and the supporting rod is used for connecting the clamping block and the inserting plate. According to the utility model, when the template main bodies are fixed on the ground, the displacement condition of the two adjacent template main bodies can be effectively limited, multi-step operation is not needed, and the operation is simpler and more convenient, time-saving and labor-saving when the template main bodies are spliced and fixed.

The invention belongs to the technical field of obstetrics and gynecology disease prediction, and particularly relates to a premature fetal membrane premature rupture prediction marker based on maternal circulation exosome microRNA and an application kit. According to the invention, placentas, fetal membranes and plasma exosomes of pregnant women with full-term birth and premature birth premature rupture of fetal membranes are collected for sequencing, the fetal membrane-derived exosome hsa-miR-145-3p which can be detected in the plasma exosomes is screened out in combination with a verification set, and the cell source and the premature birth promoting effect of the fetal membrane-derived exosome hsa-miR-145-3p are respectively clarified at a cell level and an animal level; and finally, by detecting the level of the plasma exosome hsa-miR-145-3p of the pregnant 12 (+ 1)-17 (+ 6) perimaternal body, the efficiency (AUC = 0.833) of the exosome in predicting the occurrence of premature rupture of fetal membranes in premature delivery is illustrated. According to the method, the high-risk crowd of the pPROM can be predicted through a noninvasive method in the early and middle stages of pregnancy, and the method has guiding significance for subsequent prevention and intervention of the high-risk crowd.

The invention discloses a blood mtDNACN-based system, method and application for evaluating an adverse pregnancy outcome risk, and the system comprises a data obtaining module which is used for obtaining blood mtDNACN detection data; the risk assessment module is used for storing a pre-constructed causal risk assessment model; and the result output module is used for outputting a risk assessment result. The model is constructed based on a Mendel randomization method, SNP significantly related to blood mtDNACN is used as a tool variable, and the lactic acid metabolism level hybrid effect is innovatively corrected, so that the lactic acid metabolism level hybrid effect of a subject is corrected without depending on lactic acid parameters of the subject. The causal association between the blood mtDNACN and the specific adverse pregnancy outcome (including gestational hypertension, preeclampsia, premature rupture of fetal membranes and the like) is accurately determined. According to the scheme provided by the invention, more reliable and anti-hybrid individualized risk assessment can be realized, and a new tool is provided for health management in the gestation period.

The invention relates to application of a motherwort stasis-removing decoction to treatment of postpartum placenta and fetal membrane residues. The invention provides a motherwort stasis-removing decoction and application thereof. The clinical effect and safety of the motherwort stasis-removing decoction on postpartum placenta and fetal membrane residue patients are researched through clinical research. The motherwort stasis-removing decoction has a remarkable clinical curative effect on postpartum placenta and fetal membrane residues, and can promote discharge of the residual placenta and fetal membrane, shorten the duration of postpartum bloody lochia, promote involution of uterus and reduce the risk of postpartum infection.

The invention relates to the field of medical care informatics, and discloses a method for predicting premature rupture of fetal membranes, which comprises the following steps: activating a differentiated data input interface according to medical institution levels, automatically acquiring environmental meteorological parameters, matching clinical indexes and the environmental meteorological parameters with a preset high-risk combinatorial logic gate, according to the method, risk identification is performed in a low-data environment through cooperation of a resource adaptive interface and a rigid logic gate, and a transparent decision closed loop is constructed by utilizing a dynamic interpretation generation mechanism, so that the algorithm efficiency is kept, and the doctor-patient trust is improved; and the applicability difficulty of a traditional probability model in primary medical treatment is effectively solved.

The invention provides an intelligent prediction system and method for prenatal complications of an obstetrical department based on multi-modal fusion of sclera characteristics and clinical indexes, and is applied to the technical field of data processing. The method comprises the following steps: performing preprocessing and fusion calculation on feature information in multi-modal data to generate fusion calculation data; the prenatal complications (such as gestational diabetes mellitus, gestational hypertension, premature rupture of fetal membranes and premature delivery) of the obstetrics department are dynamically predicted, and prediction characteristic parameters are generated; performing abnormal value filtering processing on the cross-modal feature weight, dynamically optimizing the weight in combination with a clinical and image feature correlation matrix, and generating feature weight data; processing the feature weight data to generate feature importance dynamic change data and abnormal features; processing the feature importance dynamic change data based on a preset risk judgment rule and the abnormal features to generate risk judgment data; and processing the risk judgment data and the prediction characteristic parameters to generate risk early warning information and a complication intervention instruction.

The present application relates to a kind of fetal membrane structures for variable cross-section observation tower, observation tower includes the center column of vertical arrangement, the circumference of center column is installed several outer columns, also include: several fetal membrane components, for annular structure of horizontal arrangement, fixed installation is coaxial on center column, suitable for fixed installation the steel structure of observation tower;Several limiting components, for annular structure of horizontal arrangement, and respectively coaxial self-rotation is installed on corresponding fetal membrane component;Fetal membrane component includes several legs, several legs are radially arranged along center column, limiting component is installed on several legs;Several legs are telescopic structure, the length of several legs is adjusted synchronously by rotating limiting component, to adjust the diameter of fetal membrane component.The fetal membrane structure realizes that main body of fetal membrane component does not need to be split during construction process, and only by standardization leg extension and sliding sleeve synchronous positioning can be accurately completed the adjustment of cross-sectional dimension, process is intuitive, and there is no cumulative deviation produced by independent adjustment link.

The utility model discloses a membrane rupture and amniotic fluid collection device utilizing negative pressure adsorption and rotary cutting. The membrane rupture and amniotic fluid collection device comprises an adsorber, a rotary cutting device and a vacuum generating device, the adsorber is tubular, the two ends of the adsorber are an adsorption end and an operation end respectively, a one-way membrane and a sealing cover are arranged in the adsorber, the one-way membrane is fixed to the inner wall of the adsorber, an amniotic fluid cavity is formed between the one-way membrane and an end opening of the adsorption end of the adsorber, and a negative pressure cavity is formed between the sealing cover and the one-way membrane. An operation cavity is formed between the sealing cover and the port of the operation end of the adsorber; the rotary cutting device comprises a rotary handle and a rotary cutting blade; the vacuum generating device comprises a negative pressure suction pipe and a negative pressure device. According to the utility model, the rotary cutter with the flower-shaped rotary cutting edge is used for replacing a needle, so that the fetal membrane can be broken after a fetus is separated from the fetal membrane, and the fetus is prevented from being accidentally injured. In the membrane rupturing process, micro-feeding of the tool bit can be achieved, the safety of a fetus is further guaranteed, the force and depth of the fetal membrane pulled into the device can be accurately controlled, and the membrane is ruptured accurately.

The application discloses a premature rupture of fetal membranes detection kit for gynaecology and obstetrics, and particularly relates to the field of detection kits, which comprises a box body and a collector, a partition and a buckle cover are arranged in the box body, the buckle cover is arranged above the partition, and a refrigeration chamber is arranged between the partition and the buckle cover; a test tube is arranged in the refrigeration chamber, the test tube is used for containing a dissolving solution, a plurality of extrusion protrusions are fixedly arranged in the test tube, the plurality of extrusion protrusions are arranged at equal intervals, and the plurality of extrusion protrusions are all arranged in the dissolving solution; and a collecting end is arranged at the end of the collector, and extrusion areas are arranged between the plurality of extrusion protrusions. The extrusion protrusions are arranged in the test tube, the collecting end is vertically reciprocatingly moved in the test tube, the collecting end is extruded by the extrusion protrusions, the dissolving solution is stirred by the collecting end, the sample is fully mixed with the dissolving solution, the sample residue on the collecting end is reduced, the sample is fully released, the mixing efficiency is improved, and the accuracy of a detection result is ensured.

The invention relates to the technical field of liquid detection, in particular to an intelligent detection method for premature rupture of fetal membranes, which comprises the following steps of: firstly, analyzing change characteristics of chromatographic data in a detection process according to ion strength deviation and ion strength change conditions of a base peak diagram and a total ion chromatogram in a time sequence; the sample component richness of the secretions of the detection pad is synthesized by combining the ion strength change condition; then further analyzing the chromatographic data of each biomarker, evaluating the chromatographic separation completeness of the biomarkers under the interference of other costs, and amplifying the precision of the biomarkers with higher chromatographic separation completeness in evaluating the pollution characteristics of the sample; finally, the pollution interference degree of the sample is calculated by analyzing the mass spectrum data characteristics of the biomarker and combining the chromatographic separation completeness and the sample component richness, so that the detection accuracy of the biomarker is improved under the condition of considering the pollution interference.

This invention provides a dual-segment, dual-color pH comparison catheter for clinical identification of premature rupture of membranes, belonging to the field of medical catheter technology. It includes a main catheter tube with a urine segment pH membrane and an amniotic fluid segment pH membrane sequentially arranged along the axial direction on the anterior outer wall of the main tube. The urine segment pH membrane has a color development range of pH 5.5-6.5, and its color change is a continuous gradient from yellow to green. This invention achieves zero-sampling detection under sterile conditions, highly integrating pH identification function into routine catheterization procedures. The pH value of urine and any potentially mixed amniotic fluid is simultaneously detected upon catheter insertion into the bladder, without the need for vaginal speculum, sampling swabs, or any form of secondary sterile opening. This design completely blocks the path of exogenous bacteria into the maternal reproductive tract at a physical level, thereby fundamentally and effectively reducing the incidence of clinically common chorioamnionitis and urinary tract infections, and improving perinatal medical safety and quality.

A hip lifting bolster for premature rupture of fetal membranes relates to the technical field of hip lifting and comprises a lifting assembly, a collecting assembly and a cushion cover, the lifting assembly comprises a bottom plate and an inclined plate arranged at the top of the bottom plate, the collecting assembly comprises a box body and a movable plate arranged at the top of the box body, and a flow guide opening penetrating through the movable plate is formed in the movable plate. The flow guide opening is located in the bottom of the vagina of the pregnant woman and used for guiding flowing-out amniotic fluid into the box body, and the cushion sleeve is sleeved outside the lifting assembly and the collecting assembly. The collecting assembly is located at the bottom of the vagina of the pregnant woman and used for containing amniotic fluid flowing out of the vagina of the pregnant woman, meanwhile, the cushion cover absorbs the falling amniotic fluid, the amount of the amniotic fluid flowing to a sickbed is reduced, discomfort of the pregnant woman is reduced, and the cleaning workload of medical staff is reduced.

A device for making an amniotic cavity access through a mother and method thereof is disclosed, which includes a transvaginal fetal membrane puncture assembly configured to construct the amniotic cavity access through a natural orifice of a maternal vagina, a trans maternal abdominal wall uterine fetal member puncture assembly configured to construct the amniotic cavity access through the maternal abdominal wall and / or a belly button, and an amniotic cavity combined sheath configured to form the amniotic cavity access for placing a fetus positioning surgical robotic arm and / or surgical instruments, thereby providing a safe operation channel for the implementation of an intrauterine fetal minimally invasive surgery.

In an embodiment, the present disclosure pertains to an organ-chip model having a plurality of cell culture chambers connected through arrays of microfluidic channels. In some embodiments, each cell culture chamber of the plurality of cell culture chambers include an inlet and an outlet. In some embodiments, the inlet is configured to receive at least one of a cell, cell media, or a cell stimulant. In some embodiments, at least one outlet is configured to collect effluent. In some embodiments, the organ-chip model can include, without limitation, an organ-chip model of amnion membrane, an organ-chip model of a feto-maternal interface (fetal membrane-decidua parietalis), an organ-chip model of a feto-maternal interface (placenta-decidua interface), an organ-chip model of a cervix, and combinations thereof. In some embodiments, the organ-chip model is an interconnected organ-chip model having a combination of one or more organ-chip models with interconnected cell culture chambers.

The invention provides a product capable of easily monitoring premature rupture of a fetal membrane. Provided is a wearable article having a test strip for detecting amniotic fluid-derived insulin-like growth factor binding protein 1 in vaginal secretions by immunochromatography, said test strip detecting 0.3 [mu] g / L to 25 [mu] g / L of insulin-like growth factor binding protein 1 as positive.

The utility model provides a hip raising pad for premature rupture of fetal membranes, which comprises a seat cushion structure, an inner core structure is wrapped in the seat cushion structure, the bottom of the seat cushion structure is fixedly connected with a support structure, and the support structure is embedded in the bottom end of the inner core structure. The hip lifting pad is used by a patient with premature rupture of fetal membranes, the hip is supported through the arranged concave part and the soft pad filled below the concave part, meanwhile, the hip of a pregnant woman is located in the concave part to be supported, the pregnant woman is matched with the hip of the patient, the problem that the patient with premature rupture of fetal membranes overflows amniotic fluid is avoided, and delivery smoothness is ensured; according to the lifting cushion, the probability of cesarean section can be reduced, meanwhile, the detachable cushion structure is adopted so that cleaning can be facilitated, amniotic fluid can not pollute the lifting cushion when overflowing, the supporting structure is arranged at the bottom of the lifting cushion, height adjustment can be conducted according to use requirements, follow-up cleaning is facilitated through the combined design, and the use convenience of the lifting cushion is improved.

To provide a puncture device capable of stably puncturing an egg membrane to form a small hole in artificially breaking the membrane.SOLUTION: Provided is a puncture device 1 for performing transvaginal puncturing on an egg membrane VL. The puncture device 1 includes: a cup 2 that is a cap-shaped cylindrical body with an opening 22a in a proximal end, has a recess part 23 in a distal end portion 21, has a puncture needle 24 in an inner surface of the recess part 23, and has a suction hole 23a opened; and a suction tube 3 having one end connected with the suction hole 23a of the cup 2 and the other end connectable with suction means 5.SELECTED DRAWING: Figure 2

The present invention discloses a coating alignment process after the epidermis is weakened. It includes step 1: positioning the epidermis on the weakened fetal membrane, and forming the required weakening line after completing the cold knife or rolling knife weakening on the B surface of the epidermis; step 2: fixing the above-mentioned weakened epidermis on the first fixture in reverse, and using the forward projection method to project the position of the weakening line on the A surface of the epidermis on the first fixture, and sticking white tape on the A surface of the epidermis along the position of the projection light, that is, marking the position of the weakening line of the B surface of the epidermis on the A surface of the epidermis; step 3: placing the skeleton on the second fixture, adjusting the position of the epidermis in step 2, so that the white tape on the epidermis is aligned along the position of the projection light, completing the positioning, and then heating with a hot drying gun, and manually bonding and coating the epidermis on the skeleton. The present invention solves the problem that the weakening lines of the epidermis and the skeleton are misaligned due to the inability to visually see the position of the weakening line on the B surface of the weakened epidermis during coating, thereby improving the product yield and coating efficiency.

The utility model relates to the technical field of medical instruments, in particular to a fetal membrane puncturing device for gynaecology and obstetrics, which comprises a connecting handle, the front end of the connecting handle is rotatably connected with a rotating handle, a pushing rod is arranged in the connecting handle in a sliding and penetrating mode, one end of the pushing rod extends into the rotating handle, and an external thread is arranged on the surface of the end portion of the pushing rod. And an internal thread matched with the rotating handle is arranged in the rotating handle. By adding a thread matching mechanism of the rotating handle and the pushing rod, accurate control over the feeding amount and the puncturing depth of the membrane rupturing needle is achieved, the risk caused by too deep puncturing to a fetus is reduced, the stability and accuracy of operation are remarkably improved, the uncertainty caused by manual operation is reduced, and therefore the safety of the membrane rupturing process is improved.

This invention discloses the application of MIF gene silencing in the preparation of drugs for treating premature rupture of membranes (PPROM), belonging to the fields of biomedicine and molecular biology. By collecting fetal membrane tissues from patients with PPROM and normal controls, this invention found that the expression level of MIF protein and the concentration of PGE2 were significantly increased in the PPROM group. Further investigation using siRNA technology to silence the MIF gene in human amniotic epithelial cells revealed that MIF silencing significantly reduced PGE2 levels. This invention is the first to demonstrate that MIF gene silencing can effectively treat PPROM by reducing PGE2 (inhibiting uterine contractions). This invention also provides a pharmaceutical composition containing MIF siRNA. This invention provides a novel molecular target and therapeutic strategy for the treatment of PPROM, with broad clinical application prospects.

The present application belongs to the technical field of biomedical materials, and relates to a treatment material for eye diseases, in particular to a cross-linked amniotic membrane material and a preparation method and application thereof. A mechanical method is used to separate a chorion layer of a fetal membrane, and a sponge layer and an amniotic membrane layer are retained, denoted as an amniotic membrane / sponge layer, and the amniotic membrane / sponge layer is cleaned; the amniotic membrane / sponge layer is placed under a condition of 15-40 DEG C for drying, so that the water content of the dried amniotic membrane / sponge layer is 10-20%; and the dried amniotic membrane / sponge layer is placed in a low-concentration cross-linking agent solution for cross-linking, and the cross-linked amniotic membrane material is obtained. The cross-linked amniotic membrane material prepared by the present application not only has suitable mechanical properties, is beneficial to the operation of an ophthalmic surgery, but also has a relatively fast degradation speed, avoids causing a foreign body reaction, and can avoid the damage to active substances of the amniotic membrane. The preparation method of the present application is simple and can avoid the toxic effect of a residual cross-linking agent.

The invention discloses a traditional Chinese medicine compound preparation for preventing and treating retained fetal membranes of dairy cows. The compound preparation is prepared from the following components in parts by weight: 45-55 parts of brown sugar, 10-20 parts of astragalus membranaceus, 15-25 parts of folium artemisiae argyi and 20-30 parts of motherwort. According to the formula, firstly, brown sugar and astragalus membranaceus are used for invigorating the stomach, strengthening the body resistance, improving the spleen and stomach functions of dairy cows and enhancing the qi and blood biochemical capacity of the body, so that the effect of recovering postpartum qi and blood weakness is achieved, Chinese angelica, ligusticum wallichii, prepared rehmannia root and other medicines with thick and greasy taste are not used for activating blood and enriching blood, on one hand, deficiency is not tonified, on the other hand, extravasated blood is not removed, and new blood is not generated; therefore, according to the formula, after the folium artemisiae argyi is used for warming uterus and dissipating extravasated blood, the motherwort is used for promoting blood circulation and removing blood stasis, dredging is used for tonifying, meanwhile, the brown sugar and the astragalus membranaceus are used for strengthening the spleen and stomach functions, and qi and blood are recovered by utilizing the qi and blood biochemical ability of the body, so that the body runs normally, and the fundamental purpose of treating diseases and solving the root is achieved.