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Composition for regulating Th1/Th2 cell ratio and preparation method thereof

A composition and cell technology, applied in the direction of drug combination, medical preparations containing active ingredients, food science, etc., can solve the problems of immune disorders, low immunity, unbalanced ratio, etc., to improve the symptoms of immune disorders, The effect of regulating the balance of yin and yang

Inactive Publication Date: 2013-08-21
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can be seen that most of the existing relevant health care product patents are mainly aimed at simply adjusting the imbalance of Th1 / Th2 cells and alleviating allergic symptoms, and have no obvious effect on improving the immune disorders and low immunity caused by long-term stagnation of liver qi.

Method used

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  • Composition for regulating Th1/Th2 cell ratio and preparation method thereof
  • Composition for regulating Th1/Th2 cell ratio and preparation method thereof
  • Composition for regulating Th1/Th2 cell ratio and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1 (granule)

[0019] Ingredients:

[0020] Cordyceps militaris, also known as Cordyceps militaris, Cordyceps militaris, etc., is purchased from Wuxi Shanye Fungi Co., Ltd. Radix Pseudostellaria Pseudostellaria Pseudostellariae is the dried tuber root of Radix Pseudostellariae. It tastes sweet and slightly bitter, and is slightly cold in nature. It belongs to the spleen and lung meridians. It is purchased from Jinwuxin Traditional Chinese Medicine Cooperative in Jurong City. Ginkgo biloba extract was purchased from Pizhou Fuwei Biochemical Products Co., Ltd., with flavonoids ≥ 24% and terpene lactones ≥ 6%, which met the pharmacopoeia standard.

[0021] Preparation method of the present invention:

[0022] Take 500 parts of heterophylla, 150 parts of citron, and 150 parts of bergamot, add water 6 times the total weight of the drug, decoct for 30 minutes each time, 3 times in a row, collect the filtrate and concentrate it to a thick paste. Take another 60 pa...

Embodiment 2

[0023] Embodiment 2 (powder)

[0024] Main ingredient: consistent with embodiment 1.

[0025] Preparation:

[0026] Take 300 parts of heterophylla, 100 parts of citron, and 100 parts of bergamot, add water 6 times the total weight of the drug, decoct for 30 minutes each time, 3 times in a row, collect the filtrate and concentrate it to a thick paste. Take another 50 parts of Cordyceps militaris and grind it into fine powder, then add it to the thick paste, then add 1 part of ginkgo leaf extract, dry it at 80°C after mixing, and make powder. Put it in a mixing container and mix it evenly, and pack it into 1000 bags, each bag is 2.5g.

Embodiment 3

[0027] Embodiment 3 (capsules)

[0028] Main ingredient: consistent with embodiment 1.

[0029] Preparation:

[0030] Take 700 parts of heterophylla, 300 parts of citron, and 300 parts of bergamot, add water 6 times the total weight of the drug, decoct for 30 minutes each time, 3 times in a row, collect the filtrate and concentrate it to a thick paste. Take another 100 parts of Cordyceps militaris and grind it into fine powder, add it to the thick paste, then add 5 parts of ginkgo leaf extract, dry it at 80°C after mixing, and make powder. Place in a mixing container and mix well, add an appropriate amount of 85% ethanol, mix well to make a soft material, transfer to a swing granulator, granulate, dry at 80°C, granulate, mix well, and fill with hard capsules Machine-filled in No. 0 capsules, made into 1000 capsules, 0.5g per capsule.

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Abstract

The invention relates to a composition for regulating a Th1 / Th2 cell ratio. The active ingredients of the composition are prepared by the following raw materials in parts by weight: 40-80 parts of cordyceps militaris, 300-700 parts of radix pseudostellariae, 100-300 parts of citron, 100-300 parts of fructus citri sarcodactylis and 1-5 parts of ginkgo biloba extract; and the active ingredients are extracted and prepared to form granules, powder, tablets or capsules through utilizing a convention technology. The invention further discloses an application of the composition in preparing health-care food for increasing Th1 cells, reducing Th2 cells and regulating the Th1 / Th2 cell ratio.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine health care, and in particular relates to a composition and a preparation method for regulating the ratio of Th1 / Th2 cells. Background technique [0002] The body's immune system is mainly composed of immune cells, immune organs, and immune molecules. Among them, T lymphocyte subsets are relatively active immune cells in the body's immune cells. They are divided into different subgroups according to their surface molecules and functions, mainly including human Leukocyte antigen 4 (CD4), human leukocyte antigen 8 (CD8), etc., among which CD4 cells are divided into Th1 and Th2 cells according to the secretion of cytokines. Th1 cells mainly secrete γ-interferon (IFN-γ), interleukin-2 (IL-2) and other cytokines, mediate cellular immune response, and play an important role in the induction of autoimmune diseases, among which IFN-γ can Induce the differentiation of Th1 cells while ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A23L1/29A61P37/04A23L33/00
Inventor 潘苏华高青
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE