Anthranilamide compound as well as preparation method and application thereof
A technology of anthranilamide and anthranilamide, which is applied in the field of anthranilamide compounds and their preparation, can solve problems such as poor effect, and achieve the effects of low cost, simple preparation method and remarkable effect
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 The chemical name of the anthranilamide compound in this embodiment is: 3-bromo-1-(3-chloro-2-pyridyl)-N-[4-thioformamide-2-methyl-6-( Methylcarbamoyl)-phenyl]-1H-pyrazole-5-carboxamide, its structural formula is as follows:
 The preparation method of this anthranilamide compound is as follows:
 Add 3.0g of 70wt% NaSH (0.0375mol), 1.9g of magnesium chloride (0.02mol) and 50mL of ethylene glycol dimethyl ether into a 250mL four-neck flask, stir to dissolve completely, and then add 9.5g of bromcyanogen Add tebendamide (0.02mol) into the reaction system, raise the temperature to 25°C under stirring, and keep it warm for 10-11 hours.
 After the reaction was completed, ethylene glycol dimethyl ether was distilled off under vacuum first, then 100 mL of water was added, and the pH was adjusted to 6-7 with hydrochloric acid, then stirred at below 10°C for 1 h, and filtered to obtain 9.8 g of a khaki-yellow crude product. The yield was 86.7%...
Embodiment 2～ Embodiment 4）
 The compound of each example is the same as that of Example 1.
 The preparation method of each embodiment is basically the same as that of Example 1, and the differences are shown in Table 1.
 Table 1
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