Extraction method of Crossostephium chinense flavone

Abstract

The invention relates to an extraction method of Crossostephium chinense flavone. The method is characterized by comprising the following steps: by using ethanol water as an extraction solvent, uniformly mixing Crossostephium chinense dry powder with ethanol water by liquid-solid ratio of 3-6ml / g; and then, placing the mixture in an ultrasonic / microwave-assisted extractor for extraction under the conditions of adjusting the ultrasonic powder to 50-90w and the microwave powder to 300-600W, controlling the temperature at 40-50 DEG C and processing time for 2-5 minutes. According to the method provided by the invention, the ultrasonic extraction-microwave-assisted extraction combining technology is adopted, so that Crossostephium chinense flavone is more adequately extracted, and the time for extraction by using a single method is shortened, thereby, improving the efficiency. The extract obtained can provide raw materials for further separation and analysis and product development of Crossostephium chinense flavone, and the method provides a novel thought for efficiently extracting Crossostephium chinense flavone.

Description

technical field [0001] The invention relates to an extraction method of sea hibiscus flavonoids, more specifically, relates to an extraction process of combining ultrasonic extraction-microwave assisted extraction for sea hibiscus flavonoids. Background technique [0002] At present, the extraction methods of plant active ingredients at home and abroad mainly include reflux extraction, organic solvent extraction, Soxhlet extraction, etc. These methods generally have the problem of low extraction efficiency. Organic solvent extraction refers to directly adding organic solvents to soak , the target active substance oozes out through the diffusion between molecules, which has the problems of long extraction time and low extraction rate; the reflux extraction method needs to add a certain amount of organic solvent, and the extraction is carried out by heating and reflux, which has low extraction amount and high solvent consumption , It is easy to cause environmental pollution. T...

AI Technical Summary

Problems solved by technology

[0002] At present, the extraction methods of plant active ingredients at home and abroad mainly include reflux extraction, organic solvent extraction, Soxhlet extraction, etc. These methods generally have the problem of low extraction efficiency. Organic solvent extraction refers to directly adding organic solvents to soak , the target active substance oozes out through the diffusion between molecules, which has the problems of long extraction time and low extraction rate; the reflux extraction method needs to add a certain amount of organic solvent, and the extraction is carried out by heating and reflux, which has low extraction amount and high solvent consumption , It is easy to cause environmental pollution. The Soxhlet extraction method uses the principle of solvent reflux and siphon, so that the solid matter can be extracted by a pure solvent every time, and the desired target product is obtained. However, using the Soxhlet extraction method, there is an extraction For the problems of long time and low processing capacity, the ultrasonic-microwave combined extraction technology has a huge advantage in extraction. Ultrasonic extraction mainly generates strong ultrasonic vibrations, which can accelerate the molecular movement of substances, accelerate the rupture of tissue cells, and improve Extraction volume, easy operation, and shortened extraction time; microwave-assisted extraction uses the characteristics of microwave absorption, reflection, penetration, etc., to quickly and effectively extract physiologically active substances from plant tissue cells, and significantly increase the extraction of target active ingredients. , to achieve the purpose of strengthening the extraction