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Application of SOD (Superoxide Dismutase) in preparation of medicines for treating skin diseases and pharmaceutical composition thereof as well as application and preparation method of pharmaceutical composition

A skin disease and composition technology, which is applied in the directions of drug combinations, skin diseases, and pharmaceutical formulations, can solve the problems of hormone-dependent dermatitis and cannot be used continuously for a long time, and achieve the effect of exact curative effect and high safety.

Inactive Publication Date: 2013-09-25
程玉李
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, corticosteroids cannot be used continuously for a long time because of multiple side effects, otherwise it may lead to more serious hormone-dependent dermatitis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] SOD---------0.01g Sodium Hyaluronate------0.05g

[0054] Sorbitol--------3 g Lactose-----------------0.05g

[0055] VB12---------0.02 g Potassium sorbate-----------0.01g

[0056] Add purified water to 100g

[0057] Operation process:

[0058] (1). Take part of the purified water according to the formula to fully dissolve SOD and adjust the pH value to 6--7;

[0059] (2) Add sorbitol, lactose, hyaluronic acid, VB12, and potassium sorbate in sequence, stir well, and dissolve.

[0060] (3) Sterilize, subpackage to prepare liquid, spray, aerosol or liquid dressing, subpackage and pack.

Embodiment 2

[0062] SOD---------0.5g Sodium Hyaluronate-------0.1g

[0063] Sorbitol---------10g Potassium sorbate----------0.5g

[0064] Allantoin--------0.2g Lactose--------------0.05g

[0065] Add purified water to 100g

[0066] Operation process:

[0067] (1). Take part of the purified water according to the formula to fully dissolve SOD and adjust the pH value to 6--7;

[0068] (2). Add sorbitol, hyaluronic acid, allantoin, lactose, narontosin, and potassium sorbate in sequence, and fully dissolve.

[0069] (3) Sterilize, subpackage to prepare liquid, spray, aerosol or liquid dressing, subpackage and pack.

Embodiment 3

[0071] SOD---------0.01g Sorbitol---------1g

[0072] Lactose----------0.01g VB12---------0.01g

[0073] Glycerin---------10 g Potassium sorbate---0.01g

[0074] Add purified water to 100g

[0075] (1) Take part of the purified water according to the formula to fully dissolve SOD and adjust the pH value to 6--7;

[0076] (2) Add sorbitol, lactose, glycerin, VB12, and potassium sorbate in sequence, stir well, and dissolve.

[0077] (3) Sterilize, subpackage to prepare liquid, spray, aerosol or liquid dressing, subpackage and pack.

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PUM

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Abstract

The invention relates to an application of SOD (Superoxide Dismutase) in preparation of medicines for treating skin diseases and a pharmaceutical composition thereof as well as an application and a preparation method of the pharmaceutical composition, specifically relates to application of SOD in preparation of medicines for treating allergic dermatitis, and in particular relates to application of SOD in preparation of medicines for treating contact dermatitis or solar dermatitis. 100 parts of the pharmaceutical composition comprise 0.01-5 parts of SOD. The pharmaceutical composition comprises other components in parts by weight as follows: 80-99.99 parts of a matrix, 0-10 parts of a preservative, 0-10 parts of an antioxidant, 0-20 parts of a wetting agent and 0-10 parts of a preservative. The preparation with SOD as a main active component is exact in curative effect and free from adverse effect. The pharmaceutical composition for treating allergic dermatitis (contact dermatitis and solar dermatitis) is exact in curative effect and high in safety.

Description

technical field [0001] The present invention relates to a new application of a substance in the medical field: an application of SOD in the preparation of medicines for treating skin diseases, a pharmaceutical composition containing SOD, and the use of the pharmaceutical composition containing SOD in the preparation of medicines for treating skin diseases The application in, and the preparation method of this pharmaceutical composition containing SOD. It specifically relates to the use of SOD-containing pharmaceutical composition for the treatment of allergic skin diseases, especially contact dermatitis and solar dermatitis. Background technique [0002] Allergy is an allergic reaction of the body. When allergens (such as chemical substances, ultraviolet rays, dust, etc.) enter the body, they combine with mast cells or basophils to produce leukotrienes, prostaglandins and other allergic factors. When the original ", mast cells begin to deform, resulting in allergic phenom...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/44A61P17/00A61P37/08
Inventor 程玉李
Owner 程玉李
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