Preparation method of cyclohexanone-oxime
A technology of cyclohexanone oxime and cyclohexanone, which is applied in the field of preparation of cyclohexanone oxime, can solve the problems of low conversion rate of cyclohexanone oxime, low selectivity of cyclohexanone oxime, difficulty in separation of oximation catalyst, etc.
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[0012] The preparation method of cyclohexanone oxime provided by the present invention comprises, under the presence of oximation catalyst and water, make cyclohexanone, ammonia and hydrogen peroxide contact reaction in organic solvent, wherein, described organic solvent is low carbon alkane and The mixed solvent of low carbon alcohol, described low carbon alkane is C 3 -C 10 Alkanes, the lower alcohols are C 3 -C 10 alcohol.
[0013] According to the present invention, although as long as C 3 -C 10 Alkanes and C 3 -C 10 The mixed solvent of alcohol is used as an organic solvent, which can improve the conversion rate of cyclohexanone and the selectivity of cyclohexanone oxime and promote the separation of the oximation catalyst, but in order to obtain better comprehensive effects, preferably, the low Carbon alkane is C 5 -C 10 Alkanes, the lower alcohols are C 3 -C 8 alcohol.
[0014] The present invention is not particularly limited to the amount of the lower alka...
Embodiment 1
[0036] This example is used to illustrate the preparation method of cyclohexanone oxime provided by the present invention.
[0037] Mix n-heptanol and n-hexane evenly at a weight ratio of 9:1 to obtain a composite solvent for later use.
[0038] according to figure 1 The method shown prepares cyclohexanone oxime. Continuously feed cyclohexanone, ammonia, hydrogen peroxide (concentration: 27.5% by weight), composite solvent and oximation catalyst TS-1 into the ammoximation reactor, wherein the flow rates of the above-mentioned materials are 10920kg / h, 2012kg / h, 15127kg / h, 33000kg / h and 2500kg / h. The temperature of the reaction system is controlled at 80-90° C., and the pressure is controlled at 0.35-0.4 MPa. The residence time of the material in the ammoximation reactor was 1.2 hours, and a reaction product containing oximation catalyst TS-1 was obtained. The resulting reaction product containing the oximation catalyst TS-1 is continuously introduced into a decanter for se...
Embodiment 2
[0041] This example is used to illustrate the preparation method of cyclohexanone oxime provided by the present invention.
[0042] Mix iso-octanol and n-octane evenly in a weight ratio of 3:2 to obtain a composite solvent for future use.
[0043] according to figure 1 The method shown prepares cyclohexanone oxime. Continuously feed cyclohexanone, ammonia, hydrogen peroxide (concentration: 27.5% by weight), composite solvent and oximation catalyst TS-1 into the ammoximation reactor, wherein the flow rates of the above-mentioned materials are 10920kg / h, 2012kg / h, 15127kg / h, 33000kg / h and 2500kg / h. The temperature of the reaction system is controlled at 77-85° C., and the pressure is controlled at 0.3-0.35 MPa. The residence time of the material in the ammoximation reactor was 1.5 hours, and a reaction product containing oximation catalyst TS-1 was obtained. The resulting reaction product containing the oximation catalyst TS-1 is continuously introduced into a decanter for ...
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