Extraction method of high-purity coptis total alkaloid

A total alkaloid, high-purity technology, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problem of not considering the recovery of alkaloids, not knowing how much alkaloids are taken away by precipitation, and not thinking about recycling alkaloids and other issues, to achieve the effect of low product cost, full utilization of resources, and cost reduction

CN103393780BActive Publication Date: 2015-02-25重庆伊士腾生物科技有限公司

12 Cites 0 Cited by

Patent Information

Authority / Receiving Office: CN · China
Patent Type: Patents(China)
Current Assignee / Owner: 重庆伊士腾生物科技有限公司
Publication Date: 2015-02-25

Smart Images

Figure 1

Patent Text Reader

Abstract

The invention relates to an extraction method of high-purity coptis total alkaloid, which comprises the following steps: preparing a raw material (coptis or coptis fibril or coptis ash), pulverizing (not required if the raw material is coptis fibril or coptis ash), immersing in 0.1-5% sulfuric acid, heating and extracting four times, filtering, neutralizing with calcium oxide (or calcium hydroxide), filtering, washing the precipitate, preconcentrating, regulating the acid, precipitating with sodium chloride, filtering, recovering alkaloid from the mother liquor, and drying the precipitate to obtain the coptis total alkaloid product. The main active components of the product are coptis effective components, such as berberine, coptisine, palmatine, epiberberine, jateorhizine and the like; the coptis total alkaloid content is more than 50%; and the berberine content is more than 25%. The product provided by the invention has favorable actions of lowering blood sugar and blood fat, losing weight and the like, and is an ideal raw material for treating diabetes and cardiovascular diseases.

Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to biological extraction technology, in particular to a high-purity Coptis chinensis total alkaloid extraction technology. Background technique

[0002] Coptis chinensis was first recorded in "Shen Nong's Materia Medica" and listed as top grade. Coptis chinensis is bitter in taste, cold in nature, and has the functions of purging fire, detoxifying, clearing away heat, and drying dampness. For dysphoria, confusion, upset and insomnia, hot and humid fullness, vomiting, abdominal pain and diarrhea, conjunctival congestion and swelling, sore tongue, eczema, burns, vomiting blood, epistaxis, etc. The results of modern pharmaceutical research show that the main active ingredient of Coptis chinensis is the total alkaloids of Coptis chinensis, mainly including berberine (berberine), palmatine, coptisine, epiberberine and jatrorrhizine, etc. ("Chinese Pharmacopoeia" 2010 edition) ; Coptis (sugar) has a wide range of pharmacological activ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine

Login to View More