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Apparatus and method for optical coherence tomography

A technology of optical coherence tomography, equipment, applied in the direction of using optical devices, eye testing equipment, applications, etc., can solve complex problems

Inactive Publication Date: 2013-11-20
WAVELIGHT GMBH
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Problems solved by technology

[0009] A disadvantage of the OCT measurement devices currently used in ophthalmology and using long-wave radiation greater than 800 nm is that the bandwidth required to achieve a sufficient axial resolution of about 10 μm or less is only achievable with complex, i.e. expensive, broadband light sources get

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  • Apparatus and method for optical coherence tomography
  • Apparatus and method for optical coherence tomography
  • Apparatus and method for optical coherence tomography

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[0038] figure 1 It is shown that the transmittance or transmittance of the cornea of ​​the human eye develops to more than 60% in a wavelength range greater than about 325 nm, and drops strongly (by starting band absorption) at shorter wavelengths. Therefore, the use of wavelengths of about 300 nm or less is restricted. It has been found that the scattering properties of the cornea in the range exceeding 300 nm to 500 nm are particularly advantageous, which results in a high signal intensity of the measurement beam deflected (scattered) by the biological tissue.

[0039] figure 2 Illustrate the axial resolution Δz of the OCT measuring device and the center wavelength λ of the wavelength spectrum of the optical radiation used by the equation (1) 0 And the relationship between the spectral width Δλ. in figure 2 It can be seen that the wavelength λ in the range of 300 to 500 nm 0 Compared with wavelengths in the range of more than 800nm, a larger axial resolution (smaller axial re...

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Abstract

There is provided an apparatus (100; 200) for recording a depth profile of a biological tissue, in particular a frontal eye section (140) of a human eye, according to the principle of optical coherence tomography, comprising a light source (101) adapted to generate a bundle (102) of light rays comprising wavelengths in a predetermined wavelength range with a predetermined bandwidth (??) and comprising an operating wavelength (?0), an interferometer arrangement having a beam splitter device (120) adapted to spatially separate the bundle of light rays generated by the light source into a reference beam (104; 204) and a measurement beam (106) directed toward the tissue, a reference beam deflection device (130; 230) adapted to deflect the reference beam, a beam superpositioning device (150) adapted to spatially superimpose the deflected reference beam onto the measurement beam deflected by the tissue into a superpositioned beam (108; 208), and a detector arrangement (160, 170; 270) for detecting information in the superpositioned beam associated with the difference of the optical path length of the reference beam and the measurement beam. The predetermined wavelength range is a range from 300 nm to 500 nm, preferably from 350 nm to 450 nm and more preferably next to 403 nm.

Description

Technical field [0001] The present invention relates to an apparatus and method for recording or measuring the depth profile of a sufficiently transparent object to be studied according to the principle of optical coherence tomography, the sufficiently transparent object, in particular, the frontal eye region of the human eye. Background technique [0002] Optical Coherence Tomography (OCT) is an interferometer research method in which, with the aid of an interferometer mechanism, light with a relatively low interference length is used to measure the distance or depth profile of a reflective (at least partially reflective) material. The advantages of optical coherence tomography technology over competing methods are the relatively large penetration depth (about 1 to 3 mm) in scattered biological tissues and the simultaneous high measurement frequency (currently, about 20 to 300 kVoxel / s can be obtained) Lower ground relatively high axial resolution (about 1 to 5μm). [0003] Regar...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61B3/12
CPCA61B3/1225A61B3/102A61B5/0066A61B3/10A61B3/12G01B9/02
Inventor 克里斯托夫·德尼茨基克劳斯·沃格勒克里斯蒂安·维尔纳克劳迪娅·格舍博特米歇尔·穆罗辛
Owner WAVELIGHT GMBH
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