Electrochemical integrated sensing chip based on digital micro-fluid technology

A digital microfluidic and sensor chip technology, applied in the field of microanalysis chips, can solve the problem that the unipolar plate digital microfluidic chip cannot automatically complete droplet generation and splitting, the detection capability of the electrochemical integrated chip is insufficient, and the droplet capacity is small, etc. problem, to achieve the effect of being beneficial to function expansion, fast and micro control, and increased sensitivity

Inactive Publication Date: 2013-11-27
FUDAN UNIV
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Problems solved by technology

[0007] Aiming at the shortcomings of the bipolar plate digital microfluidic chip in the laboratory on a chip with small droplet capacity and large contact area, while the unipolar plate digital microfluidic chip cannot automatically complete functions such as droplet generation and splitting, the

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  • Electrochemical integrated sensing chip based on digital micro-fluid technology
  • Electrochemical integrated sensing chip based on digital micro-fluid technology

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Embodiment Construction

[0032] The electrochemical integrated sensor chip based on digital microflow technology provided by the present invention mainly includes two parts, the upper and lower plates, which can be separately manufactured, and finally aligned and packaged to form a chip. The chip can be divided into electrode plates from the functional structure section and the bipolar plate section. It should be noted that this embodiment is provided for illustrative purposes and is not intended to limit the scope of the present invention in any way.

[0033] The schematic structural diagram of the novel electrochemical integrated sensor chip based on the digital microfluidic technology of the present invention is as follows: figure 1 shown. On the first insulating substrate 101 is the first electrode layer, including bipolar plate digital microfluidic chip driving electrodes E11-E13, unipolar plate digital microfluidic chip driving electrodes E21-E24 (ground electrodes are not shown) and integrated...

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Abstract

The invention belongs to the technical field of micro analysis chips and in particular relates to an electrochemical integrated sensing chip based on a digital micro-fluid technology. The chip takes the digital micro-fluid technology based on electrowetting on dielectric as the basis, and comprises two parts, namely a digital micro-fluid module for a double-layer pole plate for performing automatic operations, such as generation, transport, mixing and separation of micro-scale droplet samples, and an integrated electrochemical detection module for a single-layer pole plate, wherein in the part, the micro electrochemical system is integrated on a digital micro-fluid chip of a lower pole plate, so that the transport and real-time electrochemical detection of the droplet samples are finished; moreover, the droplet samples can be freely transported on the two parts of the chip, so that different functions are realized. The electrochemical integrated sensing chip is organically combined by the digital micro-fluid chips of the single-layer pole plate and the double-layer pole plate, the structure is novel, micro rapid and sensitive detection can be realized, and the application range of the electrochemical sensing and digital micro-fluid technology is greatly widened.

Description

technical field [0001] The invention belongs to the technical field of microanalysis chips, and in particular relates to an electrochemical integrated sensor chip based on digital microflow technology. Background technique [0002] Lab-on-a-Chip (LOC), also known as Micro Total Analysis System (Miniaturized Total Analysis System, μ-TAS), its simple definition refers to the automatic completion of various biochemical processes, miniaturization and integration of complex functions of traditional laboratory tasks The goal of the MEMS system is to integrate a complete processing and analysis process on a single device, which can complete a series of operations such as sample extraction, sample pretreatment, decomposition and separation, biochemical reactions, analysis and detection, and data processing. This technology has many advantages such as high integration, high precision, high throughput, low consumption, and intelligence, and has very good development prospects in many ...

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Application Information

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IPC IPC(8): G01N27/416B01L3/00
Inventor 余玉华陈建锋周嘉
Owner FUDAN UNIV
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