Electrochemical integrated sensing chip based on digital micro-fluid technology

Abstract

The invention belongs to the technical field of micro analysis chips and in particular relates to an electrochemical integrated sensing chip based on a digital micro-fluid technology. The chip takes the digital micro-fluid technology based on electrowetting on dielectric as the basis, and comprises two parts, namely a digital micro-fluid module for a double-layer pole plate for performing automatic operations, such as generation, transport, mixing and separation of micro-scale droplet samples, and an integrated electrochemical detection module for a single-layer pole plate, wherein in the part, the micro electrochemical system is integrated on a digital micro-fluid chip of a lower pole plate, so that the transport and real-time electrochemical detection of the droplet samples are finished; moreover, the droplet samples can be freely transported on the two parts of the chip, so that different functions are realized. The electrochemical integrated sensing chip is organically combined by the digital micro-fluid chips of the single-layer pole plate and the double-layer pole plate, the structure is novel, micro rapid and sensitive detection can be realized, and the application range of the electrochemical sensing and digital micro-fluid technology is greatly widened.

Description

technical field [0001] The invention belongs to the technical field of microanalysis chips, and in particular relates to an electrochemical integrated sensor chip based on digital microflow technology. Background technique [0002] Lab-on-a-Chip (LOC), also known as Micro Total Analysis System (Miniaturized Total Analysis System, μ-TAS), its simple definition refers to the automatic completion of various biochemical processes, miniaturization and integration of complex functions of traditional laboratory tasks The goal of the MEMS system is to integrate a complete processing and analysis process on a single device, which can complete a series of operations such as sample extraction, sample pretreatment, decomposition and separation, biochemical reactions, analysis and detection, and data processing. This technology has many advantages such as high integration, high precision, high throughput, low consumption, and intelligence, and has very good development prospects in many ...

AI Technical Summary

Problems solved by technology

[0007] Aiming at the shortcomings of the bipolar plate digital microfluidic chip in the laboratory on a chip with small droplet capacity and large contact area, while the unipolar plate digital microfluidic chip cannot automatically complete functions such as droplet generation and splitting, the present invention combines the two chip structures Together; for the insufficient detection capability of the bipolar plate electrochemical integrated chip, the chip is easy to fail, etc., the present invention integrates the electrochemical sensor into the unipolar plate digital microfluidic chip

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