Medical hydrogel moisturizing eye care mask and preparation method thereof

A hydrogel and eye patch technology, which is applied in the field of medical supplies, can solve the problems of rough skin contact of hydrogel, yellow and hard color of hydrogel, side effects of human body, etc., so as to improve the effect of skin contact and performance. , the effect of good transparency

Active Publication Date: 2014-01-08
长沙海润生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The chemical cross-linking method is fast in preparation, but due to the introduction of small molecular inorganic substances, there are side effects on the human body; the radiation cross-linking method will cause the color of the hydrogel to turn yellow and hard; although the freeze-thaw cross-linking method does not introduce side effects on the human body material, and the prepared hydrogel has the characteristics of high strength and no chipping, but the obtained hydrogel has the disadvantages of rough skin contact feeling and low transparency

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Mix 5% medical grade polyvinyl alcohol, 5% glycerin, 5% chitosan and 85% pure water by weight, stir at 60r / min for 2 hours, let it stand for 2 hours after cooling at room temperature, and cast it to obtain Hydrogel semi-finished products, these hydrogel semi-finished products are processed by freezing and thawing method (freezing temperature is -18°C, freezing time is 20h, thawing temperature is 25°C, thawing time is 6h, a total of three cycles), using cobalt 60 is a radiation source, the radiation dose is 5kGy, and the rate of the radiation dose is 0.5kGy / h for radiation sterilization to obtain the hydrogel product (eye protection patch) of the present invention.

Embodiment 2

[0020] Mix 20% medical grade polyvinyl alcohol, 1% glycerin, 0.1% chitosan and 78.9% pure water by weight, stir at 150r / min for 1 hour, let it stand for 8 hours after cooling at room temperature, and cast to obtain Hydrogel semi-finished products, these hydrogel semi-finished products are treated by freezing and thawing method (freezing temperature is -20°C, freezing time is 16h, thawing temperature is 20°C, thawing time is 8h, a total of three cycles), using cobalt 60 is a radiation source, the radiation dose is 25kGy, and the rate of the radiation dose is 0.5kGy / h to carry out radiation sterilization to obtain the hydrogel product (eye protection patch) of the present invention.

Embodiment 3

[0022] Mix 12% medical grade polyvinyl alcohol, 3% glycerin, 3% chitosan and 82% pure water by weight, stir at 100r / min for 1.5 hours, let it stand for 5 hours after cooling at room temperature, and cast to obtain Hydrogel semi-finished products, these hydrogel semi-finished products are processed by freezing and thawing method (freezing temperature is -25°C, freezing time is 12h, thawing temperature is 30°C, and thawing time is 3h, a total of three cycles), using cobalt 60 is a radiation source, the radiation dose is 15kGy, and the rate of the radiation dose is 0.5kGy / h to sterilize by irradiation to obtain the hydrogel product (eye protection patch) of the present invention.

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PUM

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Abstract

Provided are a medical hydrogel moisturizing eye care mask and a preparation method thereof. The eye care mask is prepared through the following steps that 5-20% medical-grade poval, 1-5% glycerol, 0.1-5% chitosan and pure water are mixed and stirred, the mixture is cooled at room temperature and stands still, the mixture is molded to obtain a hydrogel semi-product, and the hydrogel semi-product is processed through a freezing and thawing method and is radiated and sterilized. Thus, appropriate amount of glycerol is added, the moisturizing effect and the skin contact feeling effect of hydrogel can be improved, appropriate amount of the chitosan is added, and the bacterial and transparency effects of the hydrogel can be improved, so that the product property of a hydrogel product can be greatly improved.

Description

technical field [0001] The invention relates to a medical product, in particular to an eye-protecting patch with a moisturizing effect and a medical hydrogel as a component, and also relates to a preparation method of the eye-protecting patch. Background technique [0002] Clinically, patients with general anesthesia, facial nerve palsy, and deep coma are often accompanied by exposure keratitis caused by functional eyelid insufficiency due to corneal loss of sensation, and patients have limitations of photophobia, tearing, conjunctivitis, and foreign body sensation eye pain, so appropriate protective measures should be taken in clinical care. There are three main traditional nursing methods: covering with saline gauze, applying medicine, and using medical tape to glue the eyelids. There are certain defects in these three nursing methods. The covering time of salt water gauze is short, and the dry gauze needs to be replaced frequently. Sticking with medical tape can easily ...

Claims

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Application Information

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IPC IPC(8): A61F9/00
Inventor 谢建伟姜志华史丙华
Owner 长沙海润生物技术有限公司
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