Application of Anerning granules in preparing medicament for treating viral pneumonia

A technology of viral pneumonia and An'erning granules, applied in the field of medicine, can solve problems such as the research on the treatment of viral pneumonia by An'erning granules, and achieve the effect of protecting immune function and reducing animal death.

Inactive Publication Date: 2014-02-05
SHANDONG JINHE DRUG RES DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After further searching, there is no research on the use of other Anerning Granules in the treatment of viral pneumonia

Method used

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  • Application of Anerning granules in preparing medicament for treating viral pneumonia
  • Application of Anerning granules in preparing medicament for treating viral pneumonia
  • Application of Anerning granules in preparing medicament for treating viral pneumonia

Examples

Experimental program
Comparison scheme
Effect test

experiment example 2

[0047] Experimental example 2, the effect of Anerning Granules on respiratory syncytial virus pneumonia in vivo

[0048] 1. Experimental materials

[0049]Virus strain Respiratory syncytial virus (RSV) Long strain was quoted from the Virus Laboratory of the Institute of Virology, Chinese Academy of Preventive Medicine, and the human laryngeal carcinoma cell line (Hep-2 cells), provided by the Microbiology Laboratory of the Basic Institute of Shandong Academy of Medical Sciences; BALB / c small Rats, 5-7 weeks, half male and half female, body weight 12±1g, SPF grade, cited from Shandong University Animal Center, SPF grade animal license number: SCXX (Lu) 2012004; Ribavirin, Yantai No. 2 Pharmaceutical Factory, batch number 20110514. Anerning Granules were prepared by Jinhe Tibetan Medicine Co., Ltd., batch number 20121119.

[0050] 2. Experimental method

[0051] 1. Virus half infection dose (TCID50)

[0052] Culture with Hep-2 cell monolayer, inoculate 7 concentrations of 10...

Embodiment 1

[0074] Example 1: Anning Granules, 3g per bag, used for the preparation of drugs for the treatment of H1N1 viral pneumonia, 2 bags each time, 3 times a day.

Embodiment 2

[0075] Example 2: Anning Granules, 3g per bag, used for the preparation of drugs for the treatment of H1N1 viral pneumonia, 1 bag each time, 3 times a day.

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Abstract

The invention discloses application of Anerning granules in preparing a medicament for treating viral pneumonia. The granules have a remarkable curative effect on viral pneumonia caused by respiratory syncytial virus and influenza virus, can be used for remarkably reducing the lung index, and is in dose-effect relationship. The Anerning granules can be used for protecting experimental animal death caused by respiratory syncytial virus (RSV), and has a remarkable inhibition effect on spleen index and thymus index reduction caused by RSV, can be used for reducing animal death cased by viral pneumonia, and can be used for remarkably protecting the immunity of experimental animals.

Description

technical field [0001] The invention relates to the application of Anerning Granules in the preparation of medicines for treating viral pneumonia, which belongs to the field of medicine. Background technique [0002] At present, the pathogenic status of viruses in pneumonia has attracted more and more attention. In particular, the emergence of SARS coronavirus, avian influenza virus A (H5N1), and 2009 influenza virus A (H1N1) has once again aroused people's attention to severe pneumonia caused by respiratory virus infection. According to WHO estimates, there are about 450 million pneumonia patients worldwide each year, of which about 4 million die from the disease, accounting for 7% of the 57 million deaths. Pneumonia has become the third major cause of disease after ischemic heart disease and cerebrovascular disease. cause of death. It is well known that bacteria, especially Streptococcus pneumoniae, are the main pathogens causing community-acquired pneumonia (CAP) in adu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/16A61P11/00A61P31/16A61P31/14A61K35/413
Inventor 刘玉芹邵成雷单玉刚付素心彭坤
Owner SHANDONG JINHE DRUG RES DEV
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