Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Effervescent tablet with heat-clearing, detoxifying, wind-dispelling and phlegm-resolving effects and preparation method thereof

A technology for dispelling wind, resolving phlegm, clearing away heat and detoxification, applied to medical preparations containing no active ingredients, medical preparations containing active ingredients, antipyretics, etc. It can solve the problems of bilirubin loss, reduce drug efficacy, etc., and achieve improved Stability, masking of fishy smell, high efficacy

Active Publication Date: 2015-09-09
JINKE TIBETAN MEDICINE QINGHAI PROV
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is that in the prior art, after the β-cyclodextrin inclusion complex is performed on the artificial bezoar in the Anering pharmaceutical composition, the loss of bilirubin is serious, thereby greatly reducing the efficacy of the drug, thereby providing An effervescent tablet with high efficacy, good water solubility and strong stability, which has the functions of clearing away heat and detoxification, dispelling wind and resolving phlegm, and its preparation method

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Effervescent tablet with heat-clearing, detoxifying, wind-dispelling and phlegm-resolving effects and preparation method thereof
  • Effervescent tablet with heat-clearing, detoxifying, wind-dispelling and phlegm-resolving effects and preparation method thereof
  • Effervescent tablet with heat-clearing, detoxifying, wind-dispelling and phlegm-resolving effects and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0211] The present embodiment provides an effervescent tablet with functions of clearing away heat and detoxification, expelling wind and resolving phlegm, which is prepared by the following method:

[0212] (1) take by weighing 150g of safflower, 210g of sandalwood, after mixing, after pulverizing and sieving, adopt supercritical carbon dioxide extraction method to carry out the extraction of volatile oil, extraction pressure is 35MPa, extraction temperature is 45 ℃, extraction time 1 hour, And it is dissolved in 95% ethanol, is made into the ethanol solution of the volatile oil of 45% by volume, then adds the ethanol solution of the volatile oil into the β-cyclodextrin aqueous solution of 4% by weight, the volatile oil and the The weight ratio of β-cyclodextrin is 1:5, mix well, react at 40°C for 4 hours, refrigerate, filter with suction, and dry the precipitate in vacuum at 40°C to obtain the β-cyclodextrin inclusion complex of volatile oil;

[0213] (2) Weigh 150g of licor...

Embodiment 2

[0219] The present embodiment provides an effervescent tablet with functions of clearing away heat and detoxification, expelling wind and resolving phlegm, which is prepared by the following method:

[0220] (1) Take safflower 159.9g, sandalwood 200.1g, after mixing, after pulverizing, sieving, adopt supercritical carbon dioxide extraction method to carry out the extraction of volatile oil, extraction pressure is 35MPa, and extraction temperature is 45 ℃, extraction time 1 hours, and dissolved it in 95% ethanol to form a 55% volatile oil ethanol solution by volume, and then added the volatile oil ethanol solution to a 6% β-cyclodextrin aqueous solution by weight, and the volatile oil and The weight ratio of the β-cyclodextrin is 1:10, mix well, react at 40°C for 4 hours, refrigerate, filter with suction, and dry the precipitate in vacuum at 40°C to obtain the β-cyclodextrin inclusion compound of the volatile oil thing;

[0221] (2) Weigh 159.9g of licorice, 159.9g of alpine h...

Embodiment 3

[0227] The present embodiment provides an effervescent tablet with functions of clearing away heat and detoxification, expelling wind and resolving phlegm, which is prepared by the following method:

[0228] (1) Take safflower 170g, sandalwood 190g, after mixing, after pulverizing, sieving, adopt supercritical carbon dioxide extraction method to carry out the extraction of volatile oil, extraction pressure is 35MPa, and extraction temperature is 45 ℃, extraction time 1 hour, And it is dissolved in 95% ethanol, is made into the volatile oil ethanol solution of 50% by volume, then adds described volatile oil ethanol solution into the β-cyclodextrin aqueous solution of 5% by weight, described volatile oil and described β - The weight ratio of cyclodextrin is 1:4, mix well, react at 40°C for 4 hours, refrigerate, filter with suction, and dry the precipitate in vacuum at 40°C to obtain the β-cyclodextrin inclusion compound of volatile oil;

[0229] (2) Weigh 170g of licorice, 150g ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to an effervescent tablet with effects of clearing heat, detoxifying, dispelling pathogenic wind and reducing phlegm and a preparation method thereof. The effective pharmaceutical ingredient calculus bovis factitius in the effervescent tablet is subjected to the following treatment: firstly melting solid polyethylene glycol by heating and then dispersing the calculus bovis factitius into the melted polyethylene glycol; ensuring that the polyethylene glycol and the calculus bovis factitius form a stable dispersion body so as to improve the stability of the calculus bovis factitius medicine component; then conducting inclusion on the dispersion body through cyclodextrin to form a calculus bovis factitius inclusion compound; finally preparing the effervescent tablet with the calculus bovis factitius inclusion compound. The prepared effervescent tablet has the characteristics of good pharmaceutical effect, excellent water solubility, high stability, good taste and the like.

Description

technical field [0001] The invention relates to an effervescent tablet with functions of clearing away heat and detoxification, expelling wind and resolving phlegm and a preparation method thereof, belonging to the technical field of medicines. Background technique [0002] Anerning Granules is a classic Tibetan medicine for children. It is prepared from 9 medicinal materials, i. The medicine has the functions of clearing away heat and detoxification, dispelling wind and resolving phlegm, and has a good curative effect in clinical treatment of children with wind-heat cold, pneumonia, bronchitis and the cough and fever caused by it. In addition, considering the physiological and pathological characteristics of children, it has been clinically verified that An Er Ning Granules not only has a significant curative effect, but also has no toxic and side effects, so it is favored by patients clinically. [0003] However, since the components of the above-mentioned Anerning Granul...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K47/34A61K47/48A61K9/46A61P11/00A61P11/10A61P11/14A61P29/00A61K35/413
Inventor 王海苹杨文钰张栋李怀平
Owner JINKE TIBETAN MEDICINE QINGHAI PROV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com