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Small-view-field magnetic resonance imaging method based on single-sweep super-speed orthogonal space-time coding

A technology of orthogonal space-time coding and magnetic resonance imaging, which is applied in the direction of using nuclear magnetic resonance imaging system for measurement, magnetic resonance measurement, magnetic variable measurement, etc. problem, to achieve the effect of improving the spatial resolution

Active Publication Date: 2014-05-21
XIAMEN UNIV
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  • Claims
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Problems solved by technology

Some existing small field of view methods, including space saturation method, orthogonal excitation method, two-dimensional pulse excitation method, but the performance in the single-scan imaging sequence is not satisfactory, either there are still other signals remaining in the final data, or Very susceptible to inhomogeneous fields
Moreover, these small-field imaging methods can only obtain a small-field magnetic resonance image of a unique area in the space with one excitation. To obtain small-field images of N discretely distributed areas in the space, it is necessary to perform N excitation imaging to complete. In this case, Reduced imaging efficiency

Method used

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  • Small-view-field magnetic resonance imaging method based on single-sweep super-speed orthogonal space-time coding
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  • Small-view-field magnetic resonance imaging method based on single-sweep super-speed orthogonal space-time coding

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Embodiment

[0047] We will demonstrate the small field of view magnetic resonance imaging method based on single-scan ultra-fast orthogonal spatio-temporal encoding in live SD rats to verify the feasibility of the present invention. Experimental tests were performed on a Varian7T imager (Agilent Technologies, Santa Clara, CA, USA). The imaging sample used in the experiment was about 250 grams of living SD rats. Before the experiment, the rats were injected with 10% chloral hydrate solution at a ratio of 0.4mg / 100g to anesthetize the rats. experiment of. Before the experiment, the rat was fixed on the experimental bed and then introduced into the imager. On the operating table of the magnetic resonance imager, open the corresponding operating software of the imager, and locate the rat site of interest. Here we choose to perform coronal imaging on the brain of the rat. Then we perform tuning, shimming, frequency and power correction. According to the operation process of the flexible fie...

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Abstract

The invention discloses a small-view-field magnetic resonance imaging method based on single-sweep super-speed orthogonal space-time coding. The method comprises the following steps of: enabling protons in a space to automatically rotate in an excitation phase by virtue of the organic combination of an orthogonally-distributed space coding gradient and a linear frequency sweep pulse to acquire a secondary phase related to a space position, thus carrying out two-dimensional space-time coding on the automatic rotation of the protons in an imaging plane; for the automatic rotation of the protons in an orthogonal space-time coding space, only the automatic rotation of the protons with static phase distribution can be detected during a decoding sampling period, and according to the characteristic of orthogonal space-time coding, decoding sampling can be carried out on a plurality of randomly-distributed areas in the space by designing a decoding sampling gradient, thus acquiring the magnetic resonance data of a plurality of areas of interest finally. High-resolution reconstruction is sequentially carried out on acquired magnetic resonance data of the plurality of areas, and then the high-resolution small-view-field magnetic resonance images of the plurality of areas can be obtained finally.

Description

technical field [0001] The invention relates to a method of magnetic resonance imaging, in particular to a method for obtaining high-resolution magnetic resonance imaging of a plurality of discretely distributed regions in a single scan. Background technique [0002] Echoplanar imaging (EPI) performs rapid sampling through a series of rapidly switched gradient echoes, and a magnetic resonance image can be obtained with one excitation. With its high signal-to-noise ratio and ultra-fast imaging speed, EPI has gradually become the preferred imaging method for high-dimensional imaging such as functional neuroimaging (functional neuroimaging) and diffusion tensor imaging (diffusion tensor imaging, DTI). However, the EPI imaging method seriously affects its application effect due to its inherent problems, such as ghost and ring artifacts, and image distortion caused by non-uniform magnetic susceptibility. These issues severely damage image quality and limit spatial resolution. T...

Claims

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Application Information

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IPC IPC(8): G01R33/48
Inventor 蔡淑惠李敬蔡聪波陈林陈忠
Owner XIAMEN UNIV
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