A preparation method of traditional Chinese medicine capsules for treating migraine

Abstract

The invention provides a preparation method of a traditional Chinese medicine capsule for treating migraine, wherein the contents of the traditional Chinese medicine capsule include Gastrodia elata fine powder, dried salvia miltiorrhiza extract, water-extracted alcohol-dried extract, and volatile oil. The method comprises granulation drying, characterized in that said granulation drying adopts boiling granulation drying. The invention has low drying temperature, short drying time, few procedures, large output, high yield, uniform drug components, high active ingredient content, and the dried material is in the form of coarse powder, has good fluidity, is not easy to absorb moisture, and is easy to fill capsules.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine capsule, in particular to a preparation technology of a traditional Chinese medicine capsule for treating migraine. Background technique [0002] The Chinese patent medicine Tianju Nao'an Capsule is a traditional Chinese medicine used to treat migraine. Its prescription contains Chuanxiong, Gastrodia elata, chrysanthemum, Vitex, Ligusticum, Radix Paeoniae Alba, Salvia, Eclipta, Ligustrum lucidum, and Achyranthes bidentata, a total of 10 herbs. Usually, 150-450 parts of Chuanxiong, 100-300 parts of Tianma, 125-375 parts of Chrysanthemum, 80-240 parts of Vitex, 80-240 parts of Ligusticum edulis, 100-300 parts of Paeoniae Alba, 125-375 parts of Salvia 150-450 parts of lotus, 80-240 parts of Ligustrum lucidum, and 80-240 parts of Achyranthes bidentata, in parts by weight. [0003] The existing preparation process is as follows: crush Gastrodia elata into fine powder; reflux e...

AI Technical Summary

Problems solved by technology

[0004] In the drying process, the concentrated liquid extract is dried separately (atmospheric pressure drying or reduced pressure drying), the drying speed is slow, and it usually takes 2 to 3 days in production. The drying temperature is high, and the temperature is 70 to 95 ° C. Large energy, low output, and the dried extract needs to be crushed. Since the dried extract is porous and loose, the crushed extract powder is easy to absorb moisture and agglomerate, and has poor fluidity. It is difficult to mix the excipients evenly during the whole process of mixing

In the process of filling capsules, if the relative humidity of the environment is greater than 40%, it will quickly absorb moisture, and the fluidity of the medicine powder is poor, so it cannot be filled normally

The production process takes a long time, low output, many procedures, high production cost, and high moisture absorption of the product. Due to the long-term heating, the active ingredients in the product will degrade and reduce the quality of the product, so it is not suitable for large-scale production.