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A kind of traditional Chinese medicine gastrointestinal dissolving concentrated pill with the function of invigorating the spleen and benefiting the intestines and its preparation method

A technology for concentrating pills and traditional Chinese medicines, which can be applied to medical preparations containing active ingredients, pharmaceutical formulations, heavy metal active ingredients, etc. Function indicators, convenience of taking, effect of improving taste

Active Publication Date: 2016-06-29
GUANGZHOU BAIYUNSHAN CHENLIJI PHARMA FAB CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Chronic non-specific ulcerative colitis is a relatively common chronic inflammatory bowel disease in the colonic mucosa and submucosa that is prone to repeated attacks in clinical practice. It is characterized by lower abdominal pain, diarrhea or thin stool, mucus or blood in the stool; Recurrent, difficult to cure, and potentially malignant lesions, so the patients are very painful; because it is an autoimmune disease of unknown cause, there are few good treatment methods and drugs at home and abroad

Method used

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  • A kind of traditional Chinese medicine gastrointestinal dissolving concentrated pill with the function of invigorating the spleen and benefiting the intestines and its preparation method
  • A kind of traditional Chinese medicine gastrointestinal dissolving concentrated pill with the function of invigorating the spleen and benefiting the intestines and its preparation method
  • A kind of traditional Chinese medicine gastrointestinal dissolving concentrated pill with the function of invigorating the spleen and benefiting the intestines and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] prescription:

[0036] Gastric solution part:

[0037] Astragalus 4kg Codonopsis 4kg Amomum 1kg Peony 7kg

[0038] Angelica 1kg Surgery 5kg Cinnamon 1kg

[0039] Enteric-coated part

[0040] Corydalis 5kg Lychee core 5kg Dried ginger 1kg Licorice 5kg

[0041] Windproof 2kg woody fragrance 2kg psoralen 1kg red stone fat 7kg

[0042] preparation:

[0043] Stomach-soluble part: medicinal materials containing volatile oil (angelica, atractylodes macrocephala, amomum, cinnamon) are steam-distilled to extract volatile oil, dregs and other medicinal materials (scutellaria baicalensis, codonopsis, white peony root) are decocted twice, adding 8 times the amount each time water, extraction time is 1 hour. Filter the extract, pass it through a JD-1 (WLD) macroporous adsorption resin column, wash with water to remove water-soluble impurities, and then elute with ethanol solution with a volume fraction of 30%, and start collecting the eluate when the color of the effluent beco...

Embodiment 2

[0046] prescription:

[0047] Gastric solution part:

[0048] Astragalus 8kg Codonopsis 9.5kg Amomum 4kg Peony 12kg

[0049] Angelica 7.5kg Atractylodes macrocephala 8.5kg Cinnamon 4kg

[0050] Enteric-coated part

[0051] Corydalis 9kg Lychee core 7.5kg Dried ginger 2.5kg Licorice 8.5kg

[0052] Windproof 4.5kg Woody Fragrance 4kg Psoralen 3.5kg Red Stone Butter 12kg

[0053] preparation:

[0054] Stomach-soluble part: medicinal materials containing volatile oil (angelica, atractylodes macrocephala, amomum, cinnamon) are steam-distilled to extract volatile oil, and the dregs and other medicinal materials (scutellaria baicalensis, codonopsis, white peony root) are decocted twice, adding 12 times the amount each time water, extraction time is 2 hours. Filter the extract, pass it through a JD-1 (WLD) macroporous adsorption resin column, wash with water to remove water-soluble impurities, and then elute with ethanol solution with a volume fraction of 50%, and start collecting...

Embodiment 3

[0057] prescription:

[0058] Gastric solution part:

[0059] Astragalus 12kg Codonopsis 15kg Amomum 7kg Paeoniae Alba 17kg

[0060] Angelica 14kg Atractylodes macrocephala 12kg Cinnamon 7kg

[0061] Enteric-coated part

[0062] Yanhusuo 13kg lychee core 10kg dried ginger 4kg licorice 12kg

[0063] Windproof 7kg woody fragrance 6kg psoralen 6kg red stone fat 17kg

[0064] preparation:

[0065] Stomach-soluble part: the medicinal materials containing volatile oil (angelica, atractylodes macrocephala, amomum, cinnamon) are steam-distilled to extract the volatile oil, and the dregs and other medicinal materials (scutellaria baicalensis, codonopsis, white peony root) are decocted twice, adding 10 times the amount each time water, extraction time is 1 hour. Filter the extract, pass it through JD-1 (WLD) macroporous adsorption resin column, wash with water to remove water-soluble impurities, and then elute with ethanol solution with a volume fraction of 60%, and collect the el...

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Abstract

The invention discloses a traditional Chinese medicine stomach / intestine-soluble concentrated pill with tonifying spleen and intestine and a preparation method thereof. The stomach / intestine-soluble concentrated pill is composed of stomach-soluble compositions and intestine-soluble compositions, wherein the stomach soluble compositions comprise the following traditional Chinese medicine raw materials in parts by mass: 4-12 parts of radix astragali, 4-15 parts of radix codonopsis, 1-7 parts of amomum villosum, 7-17 parts of radix paeoniae alba, 1-14 parts of Chinese angelica, 5-12 parts of atractylodes macrocephala and 1-7 parts of cinnamomum cassia; and the intestine-soluble compositions comprise the following traditional Chinese medicine raw materials in parts by mass: 5-13 parts of rhizoma corydalis, 5-10 parts of lichee seeds, 1-4 parts of dry ginger, 5-12 parts of radix glycyrrhizae, 2-7 parts of radix saposhnikoviae, 2-6 parts of radix aucklandiae, 1-6 parts of fructus psoraleae and 7-17 parts of red halloysite. Microencapsulation technology, macroporous resin separating purifying technology, membrane separation technology and ultramicro crushing technology are employed, so that the content of crude drugs in the pill is improved and is 4-8 times of an original content.

Description

technical field [0001] The invention relates to a traditional Chinese medicine gastro-intestinal soluble concentrated pill with the function of invigorating the spleen and benefiting the intestines and a preparation method thereof. Background technique [0002] Chronic non-specific ulcerative colitis is a relatively common chronic inflammatory bowel disease in the colonic mucosa and submucosa that is prone to repeated attacks in clinical practice. It is characterized by lower abdominal pain, diarrhea or thin stool, mucus or blood in the stool; Recurrent attacks, difficult to cure, and potential malignant lesions, so patients are very painful; because it is an autoimmune disease of unknown cause, there are few good therapeutic methods and drugs at home and abroad. [0003] The applicant applied for a patent on "a preparation process of Bupi Yichang Pills" on September 5, 1987, and it was approved and announced on April 26, 1989. The patent number is 87106202. According to th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9064A61K36/9068A61K9/16A61P1/04A61P1/00A61K33/26
Inventor 钟华林谢琳彭德光谢嘉伟苏赟张怀
Owner GUANGZHOU BAIYUNSHAN CHENLIJI PHARMA FAB CO LTD