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Composition for dispelling alcohol effect and protecting liver

A technology of anti-alcoholic liver protection and composition, which is applied in the direction of drug combination, food science, plant raw materials, etc., can solve the problems of organ damage, high price, etc., and achieve the effect of reducing absorption, low cost, and wide range of drug sources

Active Publication Date: 2014-07-23
HAIMEN CITY RUITAI TEXTILE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Classification and function of anti-alcoholic drugs in the market: 1. Chemical drugs: mostly stimulants, vitamins and amino acids, which can promote alcohol decomposition and sober up, and have little effect on organ damage and chronic poisoning caused by alcohol.
2. Enzyme preparation: hangover capsules containing acetaldehyde dehydrogenase and traditional Chinese medicine, which can quickly decompose acetaldehyde and absorb alcohol, but the price is expensive

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A composition for hangover and liver protection, which is characterized in that it is prepared from the following raw materials in weight ratio:

[0025] 25 parts of kudzu flower, 25 parts of centella asiatica, 25 parts of white peony root, 22 parts of dendrobium, 22 parts of poria cocos,

[0026] 20 parts of papaya, 20 parts of dandelion, 18 parts of seabuckthorn, 18 parts of schisandra, 18 parts of clove,

[0027] 15 parts of white lentils, 15 parts of fat sea, 15 parts of licorice, 15 parts of citrus aurantium, 15 parts of pinellia,

[0028] 13 parts of Ligustrum lucidum, 13 parts of Jiaogulan, 12 parts of turmeric, 10 parts of Nepeta, 10 parts of bamboo leaves,

[0029] Guizhi 8 parts, Lycium barbarum 7 parts, Polygala 7 parts.

[0030] Its preparation method of the above-mentioned pharmaceutical composition is: take the crude drug (such as proportioning unit: gram) of the above-mentioned parts by weight. The specific operations are as follows:

[0031] 1) Take e...

Embodiment 2

[0037] 1. Drunkenness Prevention Experiment in Mice

[0038] Experimental materials: Take the anti-alcohol and liver-protecting composition prepared in Example 1 of the present invention, and make it into an aqueous solution containing 40% alcohol in commercially available Erguotou for later use.

[0039] Experimental method: Take 40 Kunming white mice, both male and female, with a body weight of 18-20g, and randomly divide them into 2 groups, 20 in each group, respectively set up the model group, the drug group of Example 1 of the present invention, and each group is administered intragastrically every day Drinking 0.4mL per mouse, the model group was given 0.1mL of water by intragastric administration 30 minutes before drinking every day, and 0.1mL was given by intragastric administration 30 minutes before drinking every day in the treatment group for 30 consecutive days. On the 5th, 10th, 15th, and 20th days, the righting reflex test was carried out on the mice, and the num...

Embodiment 3

[0048] clinical information

[0049] Case selection: Select 61 people who are prone to headaches among the long-term drinking crowd, aged 25-51 years, all of them are male.

[0050] Treatment method: take the anti-alcohol and liver-protecting composition prepared in Example 1 half an hour before and after drinking, and the amount of alcohol consumed is equivalent to the amount consumed during the previous headache.

[0051] Efficacy Judgment Criteria:

[0052] Markedly effective: no headache symptoms.

[0053] Effective: the degree of headache is reduced, and the time of headache is shortened.

[0054] Ineffective: The degree of headache has not changed.

[0055] Results: After taking the anti-alcoholic and liver-protecting composition prepared in Example 1, symptoms such as drowsiness, dizziness, headache, and nausea were significantly relieved, and they were able to move about normally. 40 people had headache symptoms disappeared, and another 17 people responded that the ...

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PUM

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Abstract

The invention relates to a composition for dispelling alcohol effect and protecting liver. The composition is prepared from the following raw materials: flos pueraria, centella asiatica, radix paeoniae alba, dendrobium nobile, poria cocos, pawpaw, dandelion, sea-buckthorn, Chinese magnoliavine, clove, dolichos lablab L., scaphium wallichii, radix glycyrrhizae, fructus aurantii immaturus, pinellia ternate, ligustrum lucidum, gynostemma pentaphylla, turmeric, nepeta cataria, bamboo leaves, cassia twig, fructus lycii and polygala tenuifolia. The above medicinal materials cooperate with each other and complement each other, the composition is capable of accelerating metabolism of alcohol in human body, increasing alcohol draining and enhancing alcohol endurance capacity of human body, and the composition is capable of improving and treating headache, dizziness, nausea and other discomfort symptoms caused by drunkenness after being eaten by a drunk person, and gives play to alcohol effect dispelling effect. The composition is substantial and reliable in treatment effect and wide in application prospect.

Description

technical field [0001] The invention belongs to the technical field of health care products, and specifically relates to a composition for relieving alcohol and protecting the liver, and a preparation method thereof. Background technique [0002] China has a long history of wine culture. Visiting relatives and friends on holidays, class reunions, work banquets, looking at daily work and life, alcohol is almost everywhere, and at the same time, excessive drinking and hurting others and self often happen. Modern research shows that the absorption and metabolism pathways of alcohol in the human body are mainly: stomach, liver, skin and respiratory system, etc. Among them, the stomach is the main place for alcohol absorption, and more than 90% of alcohol is oxidatively metabolized through the enzyme system in the liver, and the rest is oxidized and metabolized through the enzyme system in the liver. Skin, respiratory and excretion out of body. Excessive drinking and drunkenness...

Claims

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Application Information

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IPC IPC(8): A23L1/29A23L2/02A61K36/9066A61P39/02A61P1/16A23L33/00
CPCA23L2/02A23L2/52A23L29/30A23L33/00A23V2002/00A23V2250/21A23V2250/208A23V2200/334
Inventor 石宏曹红星
Owner HAIMEN CITY RUITAI TEXTILE TECH CO LTD
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