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Traditional Chinese medicine medicament for treating adrenal hypercortisolism and preparation method thereof

A technology of adrenal cortex and traditional Chinese medicine, applied in the direction of medical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of high cost, side effects, and increased economic burden of patients in western medicine, achieve significant drug efficacy, reduce cortical Alcohol, cheap effect

Inactive Publication Date: 2014-07-23
司晓东
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most patients with such diseases will choose western medicine for treatment. Although western medicine has quick results in a short period of time, it has certain side effects when taken for a long time, and the high medical cost of western medicine has increased the economic burden of patients to a certain extent.

Method used

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  • Traditional Chinese medicine medicament for treating adrenal hypercortisolism and preparation method thereof
  • Traditional Chinese medicine medicament for treating adrenal hypercortisolism and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment

[0017] A traditional Chinese medicine for treating adrenal hypercortisolism. The traditional Chinese medicine is made of the following raw materials: gentian, licorice, citrus aurantium, cornus, sealwort, Alisma, turtle shell, salvia miltiorrhiza, Poria cocos, antler, Polygala, Golden Bell, Rehmannia, Dipsacus, Cistanche, Cinnamon, Polygonatum Polygonatum, Atractylodes Rhizoma Atractylodes Rhizome, Uncaria, Jujube Seed; the raw materials include the following proportions by weight: gentian 15 grams, licorice 5 grams, citrus aurantium 10 grams, 15 grams of cornus, 15 grams of sealwort, 10 grams of Alisma, 5 grams of turtle shell, 10 grams of salvia miltiorrhiza, 15 grams of poria cocos, 5 grams of antler, 10 grams of polygala, 5 grams of golden bell, 15 grams of rehmannia, Dipsacus 5 grams, Cistanche 10 grams, cinnamon 5 grams, Polygonatum 5 grams, Atractylodes macrocephala 10 grams, Uncaria 10 grams, Zaoren 5 grams.

[0018] The preparation method process of the traditional Ch...

experiment example

[0022] Subjects of the experiment: 16 patients with equal degrees of adrenal cortisolism were divided into two groups of 8 according to the different drugs they took. Divide them into two groups according to gender, 4 people in each group.

[0023] Experiment method and time: This experiment is based on the value change of urinary 17-hydroxycorticosteroid within 24 hours to judge the condition. The normal value of urinary 17-hydroxycorticosteroid within 24 hours is: Male: 13.8~41.4μmol / 24h (5 ~ 15mg / 24h); female: 11 ~ 27.6μmol / 24h (4 ~ 10mg / 24h) more than the normal value is adrenal hypercortisolism. The urinary 17-hydroxycorticosteroids of male patients in the two groups before the experiment were 14.0-42.3μmol / 24h (6-17mg / 24h), 14.8-43.3μmol / 24h (6-18mg / 24h), 15.2 ~44.1μmol / 24h (7~19mg / 24h), 16.1~45.4μmol / 24h (8~22mg / 24h); female patients urinary 17-hydroxycorticosteroids within 24 hours: 12~28.1μmol / 24h (5~11mg / 24h), 13~29.2μmol / 24h (6~12mg / 24h), 14~30.0μmol / 24h (7~13mg / ...

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Abstract

The invention discloses a traditional Chinese medicine medicament for treating adrenal hypercortisolism and a preparation method thereof. The traditional Chinese medicine medicament for treating adrenal hypercortisolism is prepared from the following raw materials in parts by weight: 15g of gentian, 5g of liquorice, 10g of immature bitter orange, 15g of pulp of dogwood fruit, 15g of sealwort, 10g of rhizoma alismatis, 5g of turtle shell, 10g of salvia miltiorrhiza, 15g of poria cocos, 5g of cornua cervi pantotrichum, 10g of polygala tenuifolia, 5g of szechwan chinaberry fruit, 15g of raw rhizoma rehmanniae, 5g of teasel root, 10g of cistanche, 5g of cinnamon, 5g of radix polygonati officinalis, 10g of white atractylodes rhizome, 10g of uncaria and 5g of jujube kernel. The traditional Chinese medicine medicament for treating adrenal hypercortisolism is convenient to use, free of side effects, low in pharmacy cost, low in price and remarkable in effect, and does not cause potential dangers after being taken.

Description

technical field [0001] The invention relates to a traditional Chinese medicinal agent for treating adrenal hypercortisolism and a preparation method thereof. Background technique [0002] Hypercortisolism, also known as Cushing's syndrome, is caused by excess cortisol secretion by the adrenal cortex. Typical manifestations are central obesity, full moon face, buffalo hump, hanging abdomen, supraclavicular fossa fat pad sanguine appearance, purple skin, hirsutism, acne, high blood pressure, osteoporosis, and abnormal glucose tolerance. [0003] High concentrations of cortisol in the blood of patients with Cushing's syndrome can lead to decreased libido and erectile dysfunction in male patients, decreased blood testosterone levels, testicular tissue atrophy, spermatogenesis disorders, interstitial cell degeneration and seminiferous tubule fibrosis, and eventually lead to infertility. At present, most patients with such diseases will choose western medicine for treatment. Alt...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P5/38A61K35/32A61K35/56A61K35/586
Inventor 司晓东公媛媛
Owner 司晓东
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