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OPA (ortho-phthalaldehyde)-containing compound disinfectant as well as preparation method and application thereof

A technology of o-phthalaldehyde and disinfectant, applied in the direction of disinfectant, botany equipment and method, application, etc., can solve the problems such as not being able to achieve the ideal bactericidal effect, and achieve the benefits of popularization, improvement of corrosion, and good penetration Effect

Inactive Publication Date: 2014-08-06
INST OF PLA FOR DISEASE CONTROL & PREVENTION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to improve the bactericidal ability and speed of OPA, it is necessary to compound it. In recent years, domestic and foreign sterilizers have conducted beneficial explorations on the compounding of o-phthalaldehyde and launched products, but the existing products cannot achieve ideal sterilization. effectiveness, further research is needed

Method used

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  • OPA (ortho-phthalaldehyde)-containing compound disinfectant as well as preparation method and application thereof
  • OPA (ortho-phthalaldehyde)-containing compound disinfectant as well as preparation method and application thereof
  • OPA (ortho-phthalaldehyde)-containing compound disinfectant as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0040] According to the following mass percentages, each component is mixed, and the pH value is adjusted to 7.5 with potassium hydroxide to obtain the compound disinfectant provided by the invention:

[0041] 0.3% o-phthalaldehyde; double chain quaternary ammonium salt dodecyl dimethyl ammonium chloride 0.05%; cosolvent ethanol 25%; metal chelating agent edetate disodium 0.01%, sodium dihydrogen phosphate 0.01 %, disodium hydrogen phosphate 0.5%, and the balance is water.

Embodiment 2

[0043] According to the following mass percentages, each component is mixed, and the pH value is adjusted to 9.0 with potassium hydroxide to obtain the compound disinfectant provided by the invention:

[0044]0.8% o-phthalaldehyde; double chain quaternary ammonium salt dodecyl dimethyl ammonium chloride 0.4%; co-solvent ethanol 5%; metal chelating agent edetate disodium 0.05%, sodium dihydrogen phosphate 0.05% %, disodium hydrogen phosphate 2%, and the balance is water.

Embodiment 3

[0046] According to the following mass percentages, each component is mixed, and the pH value is adjusted to 7.8 with potassium hydroxide to obtain the compound disinfectant provided by the invention:

[0047] 0.6% o-phthalaldehyde; double-chain quaternary ammonium salt dodecyl dimethyl ammonium chloride 0.4%; co-solvent ethanol 5%; metal chelating agent edetate disodium 0.01%, sodium dihydrogen phosphate 0.05 %, disodium hydrogen phosphate 1.5%, and the balance is water.

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PUM

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Abstract

The invention discloses an OPA (ortho-phthalaldehyde)-containing compound disinfectant as well as a preparation method and an application thereof. The compound disinfectant comprises the following effective components: OPA, double-chain quaternary ammonium salt, a cosolvent, a metal chelator, dihydric phosphate, salt phosphate dibasic and water, and the pH of the compound disinfectant ranges from 7.5 to 9.0. According to the invention, the defect that single-component OPA cannot kill bacterial spores effectively is overcome through compounding of OPA and double-chain quaternary ammonium salt, and the application range of the OPA disinfectant is broadened. The disinfectant is suitable for high-level disinfection and sterilization of moisture-proof medical equipment which is not resistant to heat; and the compound disinfectant can be used for manual immersion disinfection and sterilization for the medical equipment and automatic mechanical flushing disinfection and sterilization, and has the characteristics of high efficiency (high-level disinfection through immersion for 20 min and sterilization for 45 min), no corrosion or pungent smell, safety, low toxicity, stable property, convenience in use and the like.

Description

technical field [0001] The invention belongs to the technical field of disinfection, and in particular relates to an ortho-phthalaldehyde compound disinfectant and its preparation method and application. Background technique [0002] Disinfection and sterilization of medical devices are directly related to the control of nosocomial infection and are the embodiment of the concept of standard prevention. There are many kinds of medical devices and supplies in hospitals, which can be roughly divided into three categories: medical devices that need to enter human blood vessels, body cavities and other sterile tissues require absolute sterility; pipelines that communicate with undamaged skin or the body, and the outside world Therapeutic instruments that are in contact with mucous membranes must be disinfected at a high level; items that do not enter human tissue and do not come into contact with mucous membranes are required to remove general bacterial propagules and lipophilic ...

Claims

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Application Information

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IPC IPC(8): A01N35/04A01P1/00A01N33/12
Inventor 袁国刚魏秋华王长德
Owner INST OF PLA FOR DISEASE CONTROL & PREVENTION
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