Non-invasive pressure measuring method for esophageal varices

A technology for esophageal flexures and veins, which is applied in the field of medical testing and can solve the problems of unconvincing pressure measurement results.

Inactive Publication Date: 2014-08-13
THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In fact, the thickness of the varicose vein wall and the diameter of the blood vessel var

Method used

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  • Non-invasive pressure measuring method for esophageal varices
  • Non-invasive pressure measuring method for esophageal varices
  • Non-invasive pressure measuring method for esophageal varices

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] Embodiment 1 Basic research, obtain the relationship between the pressure P2 impacting the blood vessel wall and the pressure P1 at the air inlet port of the gas pipeline; obtain the relationship between the pressure P2 impacting the blood vessel wall and s, and the s is the gas outlet of the gas pipeline distance from the vessel wall.

[0079] 1. The experiment of the pressure change after the air flow passes through the pipeline

[0080] 1.1 Basis: Place the ventilation pipe and the manometer in a container without the influence of air flow, and set up the pressure sensor at the gas inlet end of the gas pipeline and the position s away from the gas pipeline outlet, respectively, s and the inner diameter of the gas pipeline d The value is consistent with the actual pressure measurement, adjust the working current frequency of the air pump to change the airflow pressure, and record the airflow pressure P1 at the air inlet of the air pipeline at different times and the p...

Embodiment 2

[0127] Example 2 In vitro bionic blood vessel experiment and in vitro blood vessel experiment

[0128] 1 In vitro bionic blood vessel experiment

[0129] 1.1 Materials and methods

[0130] 1.1.2 Experimental method

[0131] (1) Place the simulated blood vessel in a horizontal position, and then connect the bionic blood vessel made of plastic to the broken end of the pipeline reserved for the simulated blood vessel, and confirm that the connection part is tight without leakage. ((Note: The composition of the simulated blood vessel instrument - make a glass tube with a scale and fix it on a fixed frame. The lower part of the glass tube is connected to a horizontally placed plastic tube, and the other end of the plastic tube is connected to a tee tube, cut off the middle part of the plastic tube, and the broken end part is used to connect the simulated blood vessel)

[0132](2) Open the three-way valve at one end of the simulated blood vessel, inject normal saline from the upp...

Embodiment 3

[0174] Embodiment 3 animal blood vessel experiment

[0175] 1 Research Background

[0176] At present, there are two types of extravenous manometry for esophageal varices, one is wall-attached manometry of esophageal varices, and the other is balloon manometry designed according to the principle of cuff manometry. Although there are many reports on in vitro experiments, animal experiments and clinical trials of these two types of non-invasive intravenous manometry methods, it is confirmed that these two manometry methods have clinical significance and feasibility. However, factors such as esophageal peristaltic contraction, coughing, nausea, and belching will inevitably affect the measurement results, and it is difficult to effectively reduce interference and improve accuracy. deviation. The present invention is based on the new method of airflow and laser detection technology, which is a non-contact pressure measurement without contact with the blood vessel wall, and is les...

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Abstract

The invention belongs to the field of the medical detection methods and specifically relates to a non-invasive pressure measuring method for esophageal varices. The method comprises the following steps: firstly, an air pump adjustable in air pressure is used for generating an airflow and conveying the airflow to an air delivery pipe, the air delivery pipe gets close to the esophageal varices via a biopsy channel of a gastroscope; the airflow of the air delivery pipe is vertically applied to impact the surface of the varices in a position spaced by a certain distance and the impact pressure of the airflow is gradually increased; at the moment when a vascular wall is just compressed flatly, the tension vector of the vascular wall is parallel to the vascular wall, and at this moment, the impact force of the airflow is equal to the pressure of the vein. The method is used for realizing truly non-invasive pressure measurement by virtue of non-contact detection, namely compressing the blood vessels by use of the airflow. The method is capable of effectively avoiding interference caused by the varices of various forms on pressure measurement; provided by bionic verification tests and animal experiments, the method is high in accuracy and has clinical use value.

Description

technical field [0001] The invention belongs to the field of medical detection methods, and in particular relates to a non-invasive pressure measurement method for esophageal varices. Background technique [0002] Esophageal varices (EV) are a common complication in patients with liver cirrhosis, and about half of patients with liver cirrhosis have esophageal varices when they are diagnosed with cirrhosis. The main symptom of EV is rupture and hemorrhage, and the higher the grade of liver function, the higher the mortality rate of EV rupture and hemorrhage. Therefore, for patients with liver cirrhosis, it is particularly important to find out the high-risk groups of EV bleeding in time, predict the bleeding tendency in advance, and formulate a reasonable treatment plan. [0003] Since the 1950s, numerous studies on esophageal variceal pressure have shown that excessive esophageal variceal pressure is the main factor causing esophageal variceal rupture and bleeding. Scholar...

Claims

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Application Information

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IPC IPC(8): A61B5/0215
Inventor 张瑞黄飞舟胡成欢刘应龙刘浔阳聂晚频
Owner THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
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