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Traditional Chinese medicine composition for nerve regeneration after cerebral arterial thrombosis and preparation method thereof

A technology for ischemic stroke and nerve regeneration, applied in the field of medicine, can solve the problems of lack of effective treatment drugs for cerebral ischemia or cerebral infarction, high drug prices, etc. effect of blood supply

Inactive Publication Date: 2014-08-20
杨献华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Aiming at the lack of effective drugs for the treatment of cerebral ischemia or cerebral infarction in the current medical practice and the high price of the existing technology, the present invention provides a drug for nerve regeneration after ischemic stroke

Method used

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  • Traditional Chinese medicine composition for nerve regeneration after cerebral arterial thrombosis and preparation method thereof
  • Traditional Chinese medicine composition for nerve regeneration after cerebral arterial thrombosis and preparation method thereof
  • Traditional Chinese medicine composition for nerve regeneration after cerebral arterial thrombosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1 Chinese medicine composition mixture of the present invention

[0030] Prescription: 15 parts of Morinda officinalis, 6 parts of black medicine, 10 parts of pomegranate peel, 10 parts of Akebia, 10 parts of Fritillaria achyranthes, 20 parts of Achyranthes bidentata, 20 parts of Salvia miltiorrhiza, 10 parts of sarcophagus, 5 parts of Chuanxiong, Qingyu 8 parts, 15 parts of Cortex Phellodendri, 7 parts of Burdock Fructus, 10 parts of Cnidium Fructus, 10 parts of Licorice.

[0031] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 75% (v / v), let it stand for 24 hours, take the superna...

Embodiment 2

[0032] Embodiment 2 Chinese medicine composition tablet of the present invention

[0033] Prescription: 15 parts of Morinda officinalis, 6 parts of black medicine, 10 parts of pomegranate peel, 10 parts of Akebia, 10 parts of Fritillaria achyranthes, 20 parts of Achyranthes bidentata, 20 parts of Salvia miltiorrhiza, 10 parts of sarcophagus, 5 parts of Chuanxiong, Qingyu 8 parts, 15 parts of Cortex Phellodendri, 7 parts of Burdock Fructus, 10 parts of Cnidium Fructus, 10 parts of Licorice.

[0034] Preparation method: Take each medicinal material of the above weight components, add water 10 times the total weight of the medicinal materials, soak for 60 minutes, decoct once, 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.25 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 80% (v / v), let it stand for 24 hours, take the supernatant,...

Embodiment 3

[0035] Embodiment 3 Chinese medicine composition capsule of the present invention

[0036] Prescription: 15 parts of Morinda officinalis, 6 parts of black medicine, 10 parts of pomegranate peel, 10 parts of Akebia, 10 parts of Fritillaria achyranthes, 20 parts of Achyranthes bidentata, 20 parts of Salvia miltiorrhiza, 10 parts of sarcophagus, 5 parts of Chuanxiong, Qingyu 8 parts, 15 parts of Cortex Phellodendri, 7 parts of Burdock Fructus, 10 parts of Cnidium Fructus, 10 parts of Licorice.

[0037] Preparation method: Take the medicinal materials of the above weight components, add water 8 times the total weight of the medicinal materials, soak for 45 minutes, decoct 4 times for 1.5 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.2 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 90% (v / v), let it stand for 24 hours, take the supe...

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Abstract

The invention belongs to the field of medicines, relates to a traditional Chinese medicine composition, and particularly relates to a traditional Chinese medicine composition for nerve regeneration after cerebral arterial thrombosis and application thereof in preparation of a medicament for preventing nerve regeneration after cerebral arterial thrombosis. Aiming at the problem of large hepatotoxicity of the traditional chemotherapeutic medicament for an ischemic cerebrovascular disease, the traditional Chinese medicine composition for nerve regeneration after cerebral arterial thrombosis provided by the invention comprises the following components in parts by weight: 15 parts of morinda officinalis, 6 parts of lindera aggregata, 10 parts of pericarpium granati, 10 parts of akebiaquinata, 10 parts of thunberg fritillary bulb, 20 parts of radix achyranthis bidentatae, 20 parts of salviae miltiorrhizae, 10 parts of sarcandra glabra, 5 parts of ligusticum wallichii, 8 parts of feather cockscomb seed, 15 parts of golden cypress, 7 parts of burdock, 10 parts of fructus cnidii and 10 parts of liquorice. The traditional Chinese medicine composition has a good treatment effect on the nerve regeneration after the cerebral arterial thrombosis, and has significant clinical popularization value.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for nerve regeneration after ischemic stroke, which belongs to the technical field of medicine. Background technique [0002] Ischemic cerebrovascular disease (ICVD) accounts for about 80% of all cerebrovascular diseases. It has the characteristics of high morbidity, disability and cure rate, and has become one of the diseases that seriously endanger human health. Ischemic cerebrovascular disease is one of the most important diseases in cerebrovascular diseases. It is a sudden imbalance between the supply and demand of oxygen and other nutrients provided by the local blood circulation and the metabolic needs of neurons, which eventually leads to the central area of ​​ischemia. A class of diseases in which neurons are damaged. Transient ischemic attack referred to as TIA, also known as transient ischemic attack or small stroke, it is due to the short-term insufficient blood supply of t...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61P9/10A61P25/00
Inventor 曹现娥
Owner 杨献华
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