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Application of cydiodine to treatment of keratoconjunctivitis

A technology of cydidinium iodine and eye drops, which is applied in the field of medicine and can solve the problems of eye irritation and inability to be widely used.

Inactive Publication Date: 2014-09-24
BEIJING HUMANWELL JUNWEI PHARM TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Since the eyes are a sensitive organ, the existing iodine preparations are obviously irritating to the eyes, so they cannot be used in other application fields such as chronic pharyngitis, Candida albicans infectious stomatitis, oral ulcers, and chronic gingivitis. , periodontal inflammation and erosive lichen planus, etc.

Method used

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  • Application of cydiodine to treatment of keratoconjunctivitis
  • Application of cydiodine to treatment of keratoconjunctivitis
  • Application of cydiodine to treatment of keratoconjunctivitis

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0059] Preparation example 1: the preparation of cediodine tablet

[0060] Formula (measured by the amount per tablet)

[0061] Cediiodine: Contains 1 mg of available iodine (I),

[0062] Glucose: 50mg,

[0063] Potassium Hyaluronate: 3mg.

[0064] Preparation method: fully mix cediodine and potassium hyaluronate, and then fully mix with glucose; wet granulate the mixed powder material with 50% ethanol, dry, and compress into tablets to make tablets containing 1 mg of available iodine (I) Agent, aluminum-plastic composite film sealed package, to get that, the sample is recorded as Ex1.

preparation example 2

[0068] Preparation example 2: the preparation of cediodine tablet

[0069] Formula (measured by the amount per tablet)

[0070] Cediiodine: Contains 1 mg of available iodine (I),

[0071] Mannitol: 50mg,

[0072] Potassium Alginate: 3mg.

[0073] Preparation method: refer to the method of Preparation Example 1, and this sample is marked as Ex2.

preparation example 3

[0076] Preparation example 3: the preparation of cediodine tablet

[0077] Formula (measured by the amount per tablet)

[0078] Cediiodine: Contains 1 mg of available iodine (I),

[0079] Glucose: 30mg,

[0080] Potassium Alginate: 5mg.

[0081]Preparation method: refer to the method of preparation example 1, and this sample is marked as Ex3.

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Abstract

The invention relates to an application of cydiodine to treatment of keratoconjunctivitis and particularly relates to a solid pharmaceutical composition used to be dropped into eyes. The solid pharmaceutical composition comprises cydiodine and a diluent. The invention also provides a medicine box product comprising a packaging box, the solid pharmaceutical composition packaged in the packaging box and a solvent for dissolving the solid pharmaceutical composition. The solid pharmaceutical composition provided by the invention can be used for preventing and treating inflammatory diseases of eyes, such as bacterial or viral inflammatory diseases on parts such as conjunctiva, cornea and the like.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to the use of cediodine for treating keratoconjunctivitis, in particular to the use of cediodine for treating keratitis and / or conjunctivitis. The present invention also provides a pharmaceutical composition for treating keratitis and / or conjunctivitis, which contains cediiodine. Using the composition of the present invention to treat eye keratitis and / or conjunctivitis has excellent effect, and has low irritation to eyes. Background technique [0002] It is known that iodine molecules can directly halogenate bacterial proteins, and non-selectively kill various microorganisms, including bacterial propagules, fungi, and spores. [0003] Many iodine preparations have been used clinically, such as povidone iodine and its preparations recorded in the Chinese Pharmacopoeia 2010 edition. The main dosage forms of antiseptics include creams, suppositories, solutions, and gels. [0004] An...

Claims

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Application Information

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IPC IPC(8): A61K33/18A61K47/48A61P31/04A61P31/12A61P27/02
Inventor 高永良陈登建闫汝锋王学智汲守信
Owner BEIJING HUMANWELL JUNWEI PHARM TECH CO LTD
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