Isoplanar microneedle array and manufacturing method thereof

Abstract

The invention relates to an isoplanar microneedle array and a manufacturing method thereof. The isoplanar microneedle array comprises coplanar microneedles and a base plate, wherein each coplanar microneedle comprises one or more than one needle point and a base which is connected with the needle point, the needle point and the base are in a same plane, and more than two coplanar microneedles are assembled on the base plate. The manufacturing method of the isoplanar microneedle array comprises the steps of utilizing the isoplanar microneedle array as a main die, manufacturing a negative die which can be reused by utilizing a reverse die casting technology, and then manufacturing the isoplanar microneedle array by using the reverse die casting technology again. The isoplanar microneedle array and the manufacturing method which are disclosed by the invention have the beneficial effects that the shape of the needle points of the coplanar microneedles is easily controlled, the quality of the needle points is good, the needle points, the needle shape and the needle length can be ensured by utilizing the microneedle array assembled by multiple coplanar microneedles side by side, and the microneedle density requirement can be met; technologies which are used during a microneedle array manufacturing process are all more mature and are easily realized, the isoplanar microneedle array assembled side by side is just used for the main die which is used for manufacturing the negative die in a reverse die casting way if the technologies are used for batch production, the use times are few, the finished product rate of the coplanar microneedles can be ensured, and the manufacturing cost of the microneedle array is reduced.

Description

technical field [0001] The invention relates to the technical field of medical cosmetic devices and microneedles for medical injection, in particular to a non-planar microneedle array and a manufacturing method thereof. Background technique [0002] Microneedle transdermal drug delivery is an emerging drug delivery technology. By pressing the microneedles, a large number of micron-sized pores are generated in the stratum corneum and epidermis of the skin, and the drug penetrates into a large number of blood vessels in the dermis of the skin through these pores, thereby achieving Transdermal administration. Microneedles can achieve integrated, portable, painless, precise, and efficient drug delivery during the treatment process, and have unparalleled advantages in diabetes treatment, chemotherapy, and vaccination. In addition, due to the sharp tip and small size of the microneedle, there will be no pain or bleeding when administering the drug, and the minimally invasive smal...

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is: the height of the existing different-plane microneedle tips is limited, and the manufacturing process is complicated

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