Preparation and application of 4-chlorine-3-ethyl-1-methyl-N'-(2-substituted phenoxy acetyl)-1H-pyrazol-5-carbohydrazide compounds
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A technology of phenoxyacetylhydrazine and phenoxyacetyl, applied in 4-chloro-3-ethyl-1-methyl-N'-(2-substituted phenoxyacetyl)-1H-pyrazole- The preparation and application fields of 5-carbohydrazide compounds achieve the effects of convenient operation, improved purity and yield, and improved reaction efficiency
Active Publication Date: 2014-12-10
YIFAN AGRI CHEM PLANT ZHEJIANG PROV
View PDF4 Cites 11 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
[0008] However, no information on 4-chloro-3-ethyl-1-methyl- N' -(2-substituted phenoxyacetyl)-1 H -Reports on the Synthesis of Pyrazole-5-carbohydrazides and Their Biological Activities
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention discloses preparation and application of 4-chlorine-3-ethyl-1-methyl-N'-(2-substituted phenoxy acetyl)-1H-pyrazol-5-carbohydrazide compounds. The preparation comprises the following steps: carrying out backflow reaction on thionyl chloride and N-methyl-3-ethyl-4-chloride pyrazole carboxylic acid for 1h to obtain a compound (II), putting the mixed liquor of a compound (III), an organic solvent and an acid-binding agent in a round-bottom flask, dropwise adding the compound (II) at 20-30 DEG C while stirring, then heating up to backflow reaction, carrying out TLC tracing until the raw materials are completely reacted, stopping the reaction, respectively extracting by using 50ml of water twice, drying the organic layer by anhydrous NaSO4, evaporating out the solvent under reduced pressure, and carrying out recrystallization to obtain the target compound shown in the formula (I). According to the preparation and the application, the reaction conditions are mild, the postprocessing is convenient and the total yield of the reaction is as high as 81%; and the compound has a herbicidal activity, thus laying a foundation for the research and development of new pesticides.
Description
technical field [0001] The present invention relates to a kind of 4-chloro-3-ethyl-1-methyl- N' -(2-substituted phenoxyacetyl)-1 H - Preparation and application of pyrazole-5-carbohydrazide compounds. Background technique [0002] Dihydrazide compounds are attractive due to their rapid development and wide range of applications. Among them, the biological activity of dihydrazide structural units as insect growth regulators has been widely recognized. They are widely used in pesticides, biomedical materials, electroluminescence, Liquid crystal materials and other fields also have important application value. For example, in the field of pesticides, commercialized N-tert-butyl-N'-4-ethylbenzoyl-N-3,5-dimethylbenzoylhydrazide (compound 1 , also known as tebufenozide) is safe for mammals and non-target organisms, and has high insecticidal activity against resistant pests, and has a better stomach poisoning effect on oriental armyworm and Spodoptera litura; [0003] [000...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.