Feed and drug preparation for treating fish gill rot
A technology for pharmaceutical preparations and fish feeds, applied in the field of feeds, can solve problems such as sounding the alarm on the export safety of ornamental fish products, and achieve the effects of not easy drug resistance, wide sources and high absorption rate
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[0026] The present invention also provides a preparation method of the above-mentioned pharmaceutical preparation, specifically mixing the raw material components in proportion, adding 500g to 800g of water for every 100g of the mixture, boiling for 3 to 4 hours, and filtering to obtain the first filtrate, and the filter residue is again Add 200g-300g of water, boil again for 1-2 hours, filter to obtain the second filtrate, mix the first filtrate and the second filtrate, concentrate, remove water, dry and pulverize to obtain dry powder, which is the pharmaceutical preparation.
[0027] The present invention also provides a fish feed, the raw materials of which include fish meal, soybean meal, cotton meal, calcium dihydrogen phosphate, soybean oil, wheat, vitamin premix, mineral premix, and the above-mentioned medicine for treating fish gill rot preparation.
[0028] The parts by weight of each raw material are respectively 3 parts by weight to 5 parts by weight of fish meal, 2...
Embodiment 1
[0058] Embodiment 1 Pharmaceutical preparation 1
[0059] Curcuma 35g, dandelion 30g, purslane 20g, sealwort 30g, red peony root 35g, ephedra 25g, knotweed 40g, honeysuckle 35g, gallnut 40g, rhubarb 25g, andrographis 25g, five-color plum 20g, styrax 25g, stone see wear 15g, road Mix 30g of Lutong, 25g of Geranium, 20g of Pueraria lobata, 25g of Wexgrass, 35g of Mulberry, 15g of Duck Celery and 25g of Cuscuta. For every 100g of the mixture, add 500g to 800g of water, boil for 3 to 4 hours, and filter to obtain The first filtrate and the filter residue were added with 200g to 300g of water again, boiled again for 1 to 2 hours, filtered to obtain the second filtrate, the first filtrate and the second filtrate were mixed, concentrated, water removed, dried and pulverized to obtain a dry powder, It is the pharmaceutical preparation 1.
Embodiment 2
[0060] Embodiment 2 toxicology experiment
[0061] Acute Toxicity Test
[0062] Select 20 Kunming mice, half and half female, body weight (20+2) g, provided by the Qingdao Experimental Animal Center, the pharmaceutical preparation prepared in Example 1 is dissolved in water to obtain a solution with a crude drug concentration of 1 g / ml, Gavage mice, after preliminary experiments, failed to detect oral administration of LD 50 , so measure its maximum tolerated dose, with the administration volume of 1.8ml / 10g body weight, gavage 2 times / d, interval 6h, observe 7d after administration, record animal death and toxic and side effect symptom, when experiment finishes, will All animals were processed, dissected, and the lesions of the main organs and tissues were observed with the naked eye. After 2 times of gavage with 180g of crude drug / kg, the animals moved, and no abnormalities were found in eating and drinking. After 7 days of observation, the animals died, and no major organs...
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