Molecular hybridization reaction chamber

Abstract

The invention provides a molecular hybridization reaction chamber which is characterized in that the reaction chamber is in a shape of a square box, the upper shell of the reaction chamber is provided with a plurality of inwardly dished square reaction cases; the center of each reaction case is provided with a liquid discharge hole; the lower parts of the liquid discharge holes are mutually connected through a transverse watercourse, and a drainage nozzle arranged on the lower shell of the reaction chamber is used for discharging the liquid; the watercourse is transversely led to the side wall of the reaction chamber to form a watercourse port; and the watercourse port is threaded and is tightened and sealed with a nut. The molecular hybridization reaction chamber can implement automation of the full-automatic hybridization supporting film platform, can form negative pressure inside through pumping, and can adsorb and discharge the liquid on the film surface through negative pressure, thereby obtaining the sufficient hybridization process.

Description

technical field [0001] The invention relates to the biological field, in particular to a molecular hybridization reaction chamber. Background technique [0002] Biochip technology is to immobilize a large number of probe molecules on a solid support at the same time through micro-processing technology and then hybridize with labeled sample molecules, and obtain the number and sequence of sample molecules by detecting the hybridization signal intensity of each probe molecule Information and efficient interpretation and analysis. [0003] Biochip technology is mainly used in the screening of cloned genes, the production of enzyme digestion maps, gene mutation and polymorphism analysis, disease diagnosis and prevention, drug screening, gene sequencing, etc. In addition, with the continuous development of biochips, the application in clinical diagnosis has gradually expanded, and it has also been widely used in industries such as agriculture, judicial identification, and enviro...

AI Technical Summary

Problems solved by technology

[0004] At present, most molecular hybridization uses traditional hybridization furnaces, which cannot realize fully automated hybridization, and the operation is relatively complicated, especially in the hybridization process, the rapid combination of DNA or RNA cannot be achieved, cleaning is difficult, and the hybridization time is too long

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