Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Liquid nutritional composition comprising free amino acids

A technique for free amino acids, compositions, applied in the field of amino acid-based liquid and gel-like compositions, subjects administering such compositions

Inactive Publication Date: 2015-01-14
NV NUTRICIA
View PDF7 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Furthermore, the document teaches not to select a composition with a high concentration of free amino acids as it states that a high concentration of free amino acids gives a very bitter taste

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Liquid nutritional composition comprising free amino acids
  • Liquid nutritional composition comprising free amino acids
  • Liquid nutritional composition comprising free amino acids

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0094] Table 1 shows that the particles / crystals unexpectedly disappeared when the dry weight content was increased above 40% when assessed by microscopy. Keep all the ingredients the same except for the amino acid content. A similar experiment was performed by increasing corn syrup solids (digestible carbohydrates) while keeping all (al) other ingredients the same (with 20 g amino acids / 100 ml), with similar results. It was concluded that by increasing the dry weight to at least 40%, particulate matter unexpectedly disappeared from the product, thereby improving stability. Amino acid mixtures 1-3 together provide a complete amino acid profile according to the group of subjects (group of patients) to which the product is to be administered.

[0095] Table 1:

[0096]

[0097]

Embodiment 2a

[0099] Table 2: Product Specifications in Grams

[0100] water

[0101] Dry matter content 40.4g / 100g

Embodiment 2b

[0103] Table 3: Liquid / Unthickened Product Specifications in Grams

[0104]

[0105]

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
concentrationaaaaaaaaaa
concentrationaaaaaaaaaa
Login to View More

Abstract

The invention relates to a liquid or gelled pasteurized or sterilized composition comprising free amino acids, calcium, a digestible carbohydrate, and preferably an indigestible carbohydrate, wherein the free amino acids are present in a concentration between 5 and 30g / 100ml, and the dry weight of the total composition is at least 40g / 100ml, and preferably lower than 60 g / 100ml. The composition may in particular be used in the treatment of a human suffering from a disorder selected from the group consisting of phenylketonuria, homocystinuria, maple syrup urine disease, tyrosinaemia, propionic acidaemia, methylmalonic acidaemia, isovaleric acidaemia, urea cycle disorders and glutaric aciduria.

Description

Background technique [0001] The present invention relates to the field of amino acid-based liquid and gel-like compositions, in particular for administering such compositions to subjects suffering from inborn errors of metabolism. [0002] Dietary management of many inborn errors of metabolism requires the absence of specific amino acids. For example, phenylketonuria (PKU) patients require protein sources with as low a concentration of phenylalanine as possible. Over the years, enteral formulations based on free amino acids incorporated into nutritionally complete amino acid compositions without specific amino acids such as phenylalanine have been developed. Other inborn errors of metabolism may require different amino acid profiles. [0003] Almost all of these formulations are powder formulations that patients can mix with, for example, water, lemon juice, or other low-protein liquids. The problem with this recipe is that not all amino acids are readily soluble, and free ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/29A23L1/304A23L1/305A61P3/00A61K31/198A61K31/723A61K31/732A61K31/736A23L33/00
CPCA23L2/66A23V2250/5086A61K31/723A61K31/198A23L2/02A23V2250/70A61K31/736A23V2200/00A23V2002/00A61K33/06A23V2250/1578A23L1/3051A23V2250/506A23L1/296A23V2250/5072A23L1/304A23V2250/06A23V2250/161A23V2250/032A23L33/175A23L33/16A23L33/40A23V2200/30A23V2250/16A23V2250/60A23V2250/21A23V2250/264A23V2250/242A61K2300/00A23V2250/00A23V2200/32A61P3/00
Inventor 安德鲁·肖恩·林奇西蒙·大卫·安德斯
Owner NV NUTRICIA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com