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Pharmaceutical composition for treating bovine laminitis and preparation method of pharmaceutical composition

A technology of bovine laminitis and composition, which is applied in the direction of drug combination, medical formula, medical preparations containing active ingredients, etc., can solve the problems that cases are easy to turn into chronic cases and cannot be completely cured, so as to improve curative effect and improve The body's disease resistance and the effect of no drug residue

Inactive Publication Date: 2015-02-18
TIANJIN REBATE SCI & TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the method of treating bovine laminitis mostly adopts procaine closed injection or antihistamine drug injection. Although the disease can be quickly controlled and the symptoms can be improved, many cases tend to turn into chronic cases and cannot be completely cured.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A pharmaceutical composition for treating bovine laminitis, the components of the pharmaceutical composition and their weights are: Qingdai 3kg, Coptidis 3kg, Trichosanthes 2kg, Rehmannia 1.5kg, Bamboo leaves 1kg, Alisma 1kg, Calcium gluconate 0.5kg kg and vitamin C0.2kg.

[0019] A preparation method of a pharmaceutical composition for the treatment of bovine laminitis, the steps of the preparation method are as follows:

[0020] (1) Weigh Qingdai, Coptidis Rhizoma, Trichosanthemi Fensis, Rehmannia Root, Bamboo Leaf and Alisma Alisma respectively according to the weight ratio and add them into the pulverizer for pulverization to obtain mixture A, which is set aside;

[0021] (2) Add 8 times the amount of distilled water to the mixture A obtained in step (1), soak for 1.5 hours, ultrasonically extract for 45 minutes, decoct for 2 hours, repeat decocting twice, combine the decoction, concentrate, and obtain paste B ,spare;

[0022] (3) Weigh calcium gluconate and vitam...

Embodiment 2

[0024] A pharmaceutical composition for treating bovine laminitis, the components of the pharmaceutical composition and their weights are: 2.5kg Qingdai, 3kg Coptidis Rhizoma, 1.8kg Trichosanthum Fensis, 2kg Rehmannia, 2kg Bamboo Leaf, 1.6kg Alisma, Gluconic Acid Calcium 0.7kg and vitamin C 0.3kg.

[0025] The steps of its preparation method are the same as in Example 1.

Embodiment 3

[0027] A pharmaceutical composition for treating bovine laminitis, the components of the pharmaceutical composition and their weights are: Qingdai 4kg, Coptidis 3.5kg, Trichosanthes 2.4kg, Rehmannia 1kg, Bamboo leaves 2.3kg, Alisma 1.1kg, glucose Calcium acid 1.5kg and vitamin C 0.6kg.

[0028] The steps of its preparation method are the same as in Example 1.

[0029] clinical application experiment

[0030] In order to verify the therapeutic effect of the pharmaceutical composition for treating bovine laminitis of the present invention on natural cases of bovine laminitis, we conducted a treatment test in a cattle farm in Xiqing District, Tianjin. By administering different doses of medicines and using commonly used chemical medicines for symptomatic treatment, the therapeutic effect and optimal dosage of the pills on bovine laminitis are evaluated.

[0031] Materials and methods

[0032] 1. Experimental animals

[0033] 20 cows with laminitis were selected and fed accord...

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PUM

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Abstract

The invention relates to pharmaceutical composition for treating bovine laminitis. The composition comprises components in parts by weight as follows: 10-40 parts of indigo naturalis, 10-40 parts of coptis chinensis, 5-20 parts of radix trichosanthis, 10-40 parts of radix rehmanniae, 5-30 parts of bamboo leaves, 5-30 parts of rhizoma alismatis, 0.5-3 parts of calcium gluconate and 0.1-2 part of vitamin C. The pharmaceutical composition has a good treatment effect, has low probability of relapse, doesn't have toxic and side effects and medicine residues and is convenient to use, the cultivation cost is saved, the operation is simplified, and the bioavailability is high.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, in particular to a pharmaceutical composition for treating bovine laminitis and a preparation method thereof. Background technique [0002] Bovine laminitis is an important disease that endangers the production of dairy cows. It is an acute, subacute and chronic diffuse inflammation of the hoof dermis and horn lobules. Its clinical features are softening of hoof cutin, pain and varying degrees of lameness. Once sick, dairy cows will be unstable, have difficulty walking, and cannot bear weight on the diseased hoof; as the disease progresses, dairy cows will lie down on the ground, and their feed intake will decrease significantly, and milk production will also begin to decline, or even stop production; serious Due to reasons such as lying on the ground and not being able to afford it, they had to be eliminated. It has caused huge economic losses to the breeding industry, and it has been the fr...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P17/00A61K31/375A61K31/191
CPCA61K36/195A61K9/2068A61K31/191A61K31/375A61K36/315A61K36/428A61K36/704A61K36/718A61K36/804A61K36/884A61K36/899A61K2236/15A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 李迎梅陈庆忠安同伟
Owner TIANJIN REBATE SCI & TECH DEV
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