32 results about "Laminitis" patented technology

Disclosed are compositions useful for treating Alzheimer's disease, atherosclerosis, arteriosclerosis, osteoarthritis and other degenerative joint diseases, Huntington's chorea, Parkinson's disease, optic atrophy, retinitis pigmentosa, macular degeneration, muscular dystrophy, aging-associated degenerative processes, asthma, dermatitis, laminitis, pemphigoid, pemphigus, reactive airway disease (e.g., COPD, IAD), inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis), multiple sclerosis, rheumatoid arthritis, periodontal disease, systemic lupus erythematosus, sarcoidosis, psoriasis, type I diabetes, ischemia-reperfusion injury, chronic inflammatory diseases, geriatric wasting, cancer cachexia, cachexia associated with chronic inflammation, sick feeling syndrome, and other inflammatory and / or degenerative diseases, disorders, conditions, and processes in humans and other animals. In one embodiment, the compositions include at least 4 of the following: a MMP1 inhibitor, a MMP2 inhibitor, a MMP3 inhibitor, a MMP7 inhibitor, a MMP9 inhibitor, an ADAMTS-4 inhibitor, a MMP13 inhibitor, and a MMP14 inhibitor. In another embodiment, the compositions include a curcuminoid, a polymethoxylated flavone, a catechin, and a boswellic acid.

Embodiments of this invention include orthotic devices for treating hoof ailments, including laminitis and founder, and methods of treating the hoof ailments using an orthotic. In one embodiment, the hoof orthotic includes a platform having a heel end, a toe end, an inside and an outside edge, the heel end comprising a center section of the platform. The toe end includes a first tip and a second tip having a space therebetween such that the toe end is not enclosed. The platform includes an upper hoof contact surface and a lower surface, the upper surface being elevated at the heel end of the platform and sloping such that the heel end has a greater vertical height than the toe end. The orthotic also includes attachment means that extend vertically from the platform for attaching the orthotic to the animal hoof. The orthotic can be made from a resilient and / or elastomeric material that may also provide cushioning and fitting advantages.

An equine boot assembly and system providing a heel lifting adjustable wedge (inflatable bladder or other suitable means) to lift the heel section of an equine hoof and optionally providing a shock absorbing cushioning pad and frog support. Lifting the heel has many benefits including relieving and reducing the consequences of laminitis by reducing the tension on the deep digital flexor tendon to allow the equine to find a more natural comfortable balance on damaged hooves. There is additionally disclosed a rocker attachment to the boot system to provide added rocker movement (better break-over) that has been shown to be beneficial in many cases.

An equine boot attachment and / or solid structure shoe that is designed to be attached on the underside of an equine boot or an equine hoof that allows the boot or hoof to roll forward, or to the side, without unnecessary bending, thus allowing an equine user to find a comfortable natural position to relieve stress on a sore, injured or diseased hoof. The rocking action allows the equine to adjust its stance to find the most comfortable position, not unlike standing in a bed of sand. This ability to find a naturally comfortable standing position is especially important for equine with lameness such as laminitis.

An inflatable horseshoe support pad for preventing and treating laminitis and navicular syndrome, among other maladies, including a body member and an inflatable bladder. The inflatable horseshoe pad is mounted between the hoof of the horse and the horseshoe with the bladder mounted on the upper surface of the body member near the heel portion so that it engages the frog of a horse's hoof when installed on the hoof. The support pad is mounted under the bladder. A frog pad can also be mounted under the support pad.

An apparatus for providing cryotherapy to an equine hoof for treatment or prevention of laminitis includes a housing configured to receive a hoof of the equine having laminitis such that at least a lower portion of the hoof is enclosed by the housing. The housing has a chamber within, in communication with a source of cooling fluid. The housing may be supported in a boot. A heat transfer surface of the housing delivers cooling to a sole area of the equine hoof, thereby treating or preventing laminitis, for example, without directly contacting the hoof with fluid. Tubing for flow of cooling fluid to and from the chamber extends upwardly along each of the legs of the equine being treated to prevent crimping or entanglement of the tubing due to movement of the equine.

An inflatable horseshoe support pad for treating laminitis and navicular syndrome, among other maladies, including a body member with a toe portion, a heel portion, an upper, hoof-facing surface and a lower, ground-facing surface. An inflatable bladder is disposed on the upper surface of the body member near the heel portion so that it engages the frog of a horse's hoof when installed on the hoof.

A method and system that incorporates spraying logic onto the sensor mat to detect and apply various liquids onto the feet of an animal. Each sensor in the sensor mat actuates a specific valve for application of the medicinal fluid without the use of relays and associated wiring. The medicinal fluid is a topical anti-inflammatory / vaso dilator to prevent swelling, hemorrhaging, and further tissue elimination, commonly known as laminitis, abscess, ulcers and white line disease. The application of the medicinal fluid can be administered to only specific animals by tagging the animals that require treatment.

A boot for treating laminitis in horses has a hoof casing snugly receiving an supporting a horny hoof wall of the laminitic hoof and a sole pivotally attached to the hoof casing such that the laminitic hoof may pivot with respect to the sole while the sole is planted on ground, thereby reducing stress on the inflamed laminae. A bearing assembly disposed between the hoof casing and the sole facilitates pivoting, and friction adjustment may be provided.

The invention relates to a traditional Chinese medicine composition for treating laminitis in dairy cows and a preparation method thereof. The traditional Chinese medicine composition comprises the following components in parts by weight: 20-25 parts of rhizoma coptidis, 15-20 parts of rhizoma dioscoeae bulbiferae, 15-25 parts of herba andrographitis, 10-18 parts of fosythia fruits, 10-15 parts of red flowers, 10-15 parts of platycodon grandiflorus, 15-20 parts of garlic and 15-25 parts of hawthorns. The traditional Chinese medicine composition disclosed by the invention is mainly used for treating laminitis in dairy cows; and the traditional Chinese medicine composition has no drug residues, and is easy to use.

A microbial adherence inhibitor specific to lactic acid producing microorganisms, in the form of fowl egg antibodies is disclosed, along with the method of making it and methods of using it. The inhibitor functions by substantially preventing the attachment or adherence of colony-forming immunogens in the rumen and intestinal tracts of host food animals. The inhibitor is made by inoculating female birds with the immunogen, allowing time for an immune response in the female bird and then harvesting the eggs that contain antibodies to the immunogen. The egg contents can be dried or used as a liquid and added to the feed or water for the host animals. Dependent upon the particular immunogen with which the female bird is inoculated, the egg antibody is used to promote the growth of food animals by improving feed conversion rates by decreasing the lactic acid production caused by the presence of certain colony-forming organisms in the animals, and to substantially reduce or eliminate the incidence of species that have been linked to very high production of lactic acid which can result in reduced performance and in acute situations, dangerously low rumen pH levels. When high levels of lactic acid are present in the rumen, rumen ulcers can form. When rumen ulcers are present other bacteria such as Fusobacterium necrophorum can escape the rumen and cause liver abscesses or laminitis, which further reduce feed conversion efficiency. Colony forming immunogens such as Streptococcus bovis (a major lactic acid producer) and Fusobacterium necrophorum can both be targeted by antibodies to enhance feed efficiency.

The invention discloses isolated endotoxemia marker polynucleotides selected from any one of 163 different polynucleotide sequences, or variants thereof. Endotoxemia related conditions are diagnosed in a test subject by aberrant expression of at least one of the endotoxemia markers or variants thereof. Of practical use, is the early diagnosis of disease, determining those animals at risk of developing endotoxemia, monitoring of an animals immune response to the disease and the enablement of better treatments. Of particular interest is the diagnosis of laminitis in hoofed animals, including horses.

The invention discloses a veterinary medicine for treating animal digestive tract diseases, which is characterized by consisting of the following Chinese herbal medicinal ingredients in part by weight: medicated leaven, roasted malt, stir-fried hawthorn, atractylodes lancea, officinal magnolia bark, dried ginger, liquorice, green tangerine peel, tangerine peel, rhubarb, sophora flavescens and Laimingzi. A preparation method of the veterinary medicine comprises the following steps: after strictly purchasing the traditional Chinese medicine on selection, air-drying or drying; grinding and sieving the powder by an 80-mesh sieve carrying out subpackaging by double-layer plastic bags according to the specification of 500g per bag. The veterinary medicine for treating the animal digestive tract diseases, which is disclosed by the invention, has curative effects of resolving phlegm, clearing away heat, helping digestion and removing accumulation, clearing the hollow viscera, assisting in digesting, eliminating food retention and relieving stagnant qi and relieving intestines and has very satisfied curative effects on gastrointestinal indigestion, food-induced laminitis, impairment and diarrhea which are caused by overeating and the like, which are caused by excessive concentrates. The veterinary medicine also can be used for treating the same symptoms of other animals.

The present invention relates to a method for substantially preventing a reduction in feed intake in an animal which occurs when said animal is administered an antibiotic, the method comprising administering to an animal in need of prevention of a reduction in feed intake, increasing doses of a composition comprising one or more antibiotics. The present invention also relates to a method for treating laminitis and fermentative acidosis in an animal in need of said treatment, the method comprising administering increasing doses of a composition comprising one or more antibiotics. The present invention further relates to a method for treating equine grass sickness and pulpy kidney in an animal in need of said treatment, the method comprising administering increasing doses of a composition comprising one or more antibiotics.

The invention relates to pharmaceutical composition for treating bovine laminitis. The composition comprises components in parts by weight as follows: 10-40 parts of indigo naturalis, 10-40 parts of coptis chinensis, 5-20 parts of radix trichosanthis, 10-40 parts of radix rehmanniae, 5-30 parts of bamboo leaves, 5-30 parts of rhizoma alismatis, 0.5-3 parts of calcium gluconate and 0.1-2 part of vitamin C. The pharmaceutical composition has a good treatment effect, has low probability of relapse, doesn't have toxic and side effects and medicine residues and is convenient to use, the cultivation cost is saved, the operation is simplified, and the bioavailability is high.

The present invention relates to the production and use of feed compositions useful in the treatment and prevention of laminitis, founder and overeating, particularly in horses and ponies. The feed composition may reduce the effects of carbohydrate overload whilst providing a controlled release of metabolizable energy to avoid excessive fermentation and lactic acid production in the hind gut. At the same time the feed composition can provide nutrition to the animal whilst avoiding overeating. The combination of controlled bulk and energy provides for a feed composition that can control the symptoms of excess energy sources in the gut which may manifest as laminitis and founder.

The present invention generally relates to methods for treating the sequela of laminitis in hoofed animals. Benefits are obtained by administering to the animals to be treated injections of Botulinum Toxin in the limb to be treated. In one embodiment, about 100 Units to 600 Units of Type A Botulinum Toxin is injected in multiple injections into the flexor digitorum profundus muscle of an animal's affected limb.

The invention discloses a traditional Chinese medicine composition for treating laminitis of cows, and belongs to the technical field of traditional Chinese veterinary medicine. The traditional Chinese medicine composition is composed of the following components in parts by weight: 25 to 45 parts of wine fried tree peony bark, 20 to 45 parts of sargentg loryvine stem, 40 to 60 parts of suberect spatholobus stem, 50 to 70 parts of garden balsam, 25 to 45 parts of artemisia anomala, 40 to 60 parts of madder, 5 to 20 parts of saffron, 40 to 60 parts of wine fried large-leaved gentian, 25 to 45 parts of peach seed, 10 to 25 parts of fritillaria cirrhosa, 40 to 60 parts of dried radix rehmanniae, 25 to 45 parts of radix angelicae stir-fried with vinegar, 25 to 45 parts of fructus perillae, 30 to 50 parts of red umbilicaria, 15 to 30 parts of achyranthes aspera, 10 to 25 parts of cassia twig, and 20 to 40 parts of licorice. The provided traditional Chinese medicine composition has the functions of clearing heat, removing toxin, activating blood circulation to dissipate blood stasis, eliminating swelling, and relieving pain, the curative effect is reliable, and there is no any side or toxic effect in clinic application.

The present invention relates to sole support pad for hoofed animals but more particularly to sole support pad for horses with laminitis or other foot problems. Said sole support pad comprises a curable resin-coating tiny expandable polystyrene balls which can be placed directly to the foot with or without shoes in a matter of seconds. It further relates to a process of producing said sole support pad comprising the steps of; coating polystyrene balls with poly-isocyanate prepolymer under dry atmosphere; allowing isocyanate and polyol to react; hardening the resin upon wetting with tertiary amine or organic peroxide solutions, and packaging coated balls in impervious package to prevent contact with atmospheric pressure.

A method for treating or preventing laminitis is provided comprising administering to an ungulate a therapeutically or prophylactically effective amount of a camelid protease inhibitor. Typically the ungulate is a horse and the camelid protease inhibitor is an inhibitor of equine metalloproteinases and equine serine proteases. The inhibitor may be isolated from blood from healthy camelid or may be generated by inoculating camelid with purified equine metalloproteinase enzymes and serine proteases or with snake venom metalloproteinases, such as those obtained from Bothrops jararaca. The inhibitor may a homodimer antibody or an antigen binding fragment of same. Also provided are compositions comprising such camelid protease inhibitors.

The invention discloses traditional Chinese medicine composition for treating porcine laminitis and belongs to the technical field of veterinary herbal medicines. The traditional Chinese medicine composition is prepared from, in parts by weight, 5-25 parts of commeline communis, 5-20 parts of herba hyperici japonici, 5-20 parts of borneol, 8-25 parts of caragana jubata, 5-20 parts of twigs of winged euonymus, 10-25 parts of wine-fried sargentodoxa cuneata, 7-22 parts of descurainia sophia, 9-25 parts of cardamine tangutorum, 5-30 parts of radix glehniae, 10-20 parts of rhizoma nardostachyos, 5-35 parts of roots or fruits of fourpetal roses, 5-22 parts of achyranthes aspera, 6-19 parts of cassia twigs and 10-25 parts of radix glycyrrhizae. The traditional Chinese medicine composition has the characteristics of clearing heat, removing toxin, activating blood, removing stasis, eliminating swelling, relieving pain and the like, is combined with modern test techniques and has a definite treatment effect and no toxic or side effect clinically.

A method for treating or preventing laminitis is provided comprising administering to an ungulate a therapeutically or prophylactically effective amount of a camelid protease inhibitor. Typically the ungulate is a horse and the camelid protease inhibitor is an inhibitor of equine metalloproteinases and equine serine proteases. The inhibitor may be isolated from blood from healthy camelid or may be generated by inoculating camelid with purified equine metalloproteinase enzymes and serine proteases or with snake venom metalloproteinases, such as those obtained from Bothrops jararaca. The inhibitor may a homodimer antibody or an antigen binding fragment of same. Also provided are compositions comprising such camelid protease inhibitors.

The invention discloses a blood-enriching and qi-tonifying compound traditional chinese lozenge and a preparation technology thereof. The blood-enriching and qi-tonifying compound traditional chinese lozenge mainly comprises bighead atractylodes rhizome, jujube, fleece-flower root, dioscorea fordii prain et burkill, jujube kernel, tuber of dwarf lilyturf, radix codonopsis, matrimony vine, alpinia officinarum hance, common fennel fruit, white peony root, semen litchi, poria cocos, pine kernel, chinese cassia tree, radix astragali, chinese angelica, ligusticum wallichii, red sage root, fructus trichosanthis, and immature bitter orange. The above raw materials are subjected to the traditional preparation process to form the lozenge. The blood-enriching and qi-tonifying compound traditional Chinese lozenge has no toxic or side effect and is scientific in compatibility and good in synergistic effect. Therefore, the blood-enriching and qi-tonifying compound traditional Chinese lozenge has the efficacies of invigorating spleen and benefiting lung, thus being suitable for the symptomatic treatment on various symptoms caused by the deficiency of qi and blood. Meanwhile, the symptoms of dizziness, tinnitus, laminitis, soreness of waist, back pain, insomnia, dreaminess, palpitations, shortness of breath, eupyrexia of hand centre and sole centre, skin dim and reluster are relieved. In addition, the lozenge prepared by the above method is reasonable in formula, simple in preparation process and good in molding effect. The bitter taste of the compound traditional Chinese lozenge is covered up by menthol, so that the compound traditional Chinese lozenge is good in mouthfeel. Therefore, the compound traditional Chinese lozenge is very convenient to take for people.

The present invention relates to a method for substantially preventing a reduction in feed intake in an animal which occurs when said animal is administered an antibiotic, the method comprising administering to an animal in need of prevention of a reduction in feed intake, increasing doses of a composition comprising one or more antibiotics. The present invention also relates to a method for treating laminitis and fermentative acidosis in an animal in need of said treatment, the method comprising administering increasing doses of a composition comprising one or more antibiotics. The present invention further relates to a method for treating equine grass sickness and pulpy kidney in an animal in need of said treatment, the method comprising administering increasing doses of a composition comprising one or more antibiotics.

The present invention relates to the production and use of feed compositions useful in the treatment and prevention of laminitis, founder and overeating, particularly in horses and ponies. The feed composition may reduce the effects of carbohydrate overload whilst providing a controlled release of metabolizable energy to avoid excessive fermentation and lactic acid production in the hind gut. At the same time the feed composition can provide nutrition to the animal whilst avoiding overeating. The combination of controlled bulk and energy provides for a feed composition that can control the symptoms of excess energy sources in the gut which may manifest as laminitis and founder.

The present invention relates to a traditional Chinese medicine composition for treating dairy cow laminitis and a preparation method for same. The traditional Chinese medicine composition comprises the following constituents in the following parts by weight: 20-25 parts of coptis chinensis, 15-20 parts of rhizoma dioscoreae bulbiferae, 15-25 parts of andrographis paniculata, 10-18 parts of fructus forsythiae, 10-15 parts of safflower, 10-15 parts of platycodon grandiflorum, 15-20 parts of garlic, and 15-25 parts of hawthorn. The traditional Chinese medicine composition provided by the present invention is mainly used for treating dairy cow laminitis, free from medicine residue, and convenient to use.

A boot for treating laminitis in horses has a hoof casing snugly receiving an supporting a horny hoof wall of the laminitic hoof and a sole pivotally attached to the hoof casing such that the laminitic hoof may pivot with respect to the sole while the sole is planted on ground, thereby reducing stress on the inflamed laminae. A bearing assembly disposed between the hoof casing and the sole facilitates pivoting, and friction adjustment may be provided.

The invention relates to a traditional Chinese medicine decoction for treating bovine laminitis and a preparation process thereof. The traditional Chinese medicine decoction includes, by weight parts,5-20 parts of tangerine peel, 5-30 parts of myrrh, 5-30 parts of rhizoma chuanxiong, 5-20 parts of carthamus tinctorius, 5-20 parts of acorus calamus, 5-20 parts of platycodon grandiflorum, 5-20 parts of radix bupleuri, 5-20 parts of licorice root, 5-25 parts of apricot kernel, 5-30 parts of officinal magnolia bark, 5-30 parts of angelica sinensis and 5-30 parts of morning glory. The traditionalChinese medicine decoction has effects of promoting blood circulation and performing detoxification, regulating qi and relieving depression, has the advantages of good absorption, quick acting, smalltoxic and side effects and almost no veterinary drug residue, and is an ideal traditional Chinese medicine decoction for treating bovine laminitis.