Comprehensive extraction technology of rosmarinic acid, ursolic acid, oleanolic acid and carnosic acid

Abstract

The invention discloses a comprehensive extraction technology of rosmarinic acid, ursolic acid, oleanolic acid and carnosic acid. The comprehensive extraction technology comprises the steps of (1) preprocessing raw materials; (2) performing reflux alcohol-extraction; (3) carrying out primary separation; (4) separating out rosmarinic acid; (5) separating out ursolic acid; (6) separating out oleanolic acid. According to the comprehensive extraction technology, the process is simple, the operation is convenient, industrial production can be easily carried out, and meanwhile, the purpose of synchronously extracting rosmarinic acid of rosemary, ursolic acid, oleanolic acid and carnosic acid is achieved, and the active ingredients of rosemary can be extracted to the maximum; the rosmarinic acid, ursolic acid, oleanolic acid and carnosic acid respectively have the purity exceeding 30%, 25%, 20% and 25%.

Description

technical field

[0001] The invention belongs to the technical field of extraction of plant active components, and in particular relates to a composite extraction process of rosmarinic acid, ursolic acid, oleanolic acid and carnosic acid. technical background

[0002] Rosemary (Rosmarinus officinalis) is a labiatae shrub, the English name is Rosemary, native to the Mediterranean Basin, northwestern Spain and Portugal. The stems, leaves, and flowers of rosemary have a strong aroma, which can refresh the mind, enhance memory, and promote blood circulation. It has therapeutic effects on nervous, digestive, and respiratory diseases; when epidemics break out in Europe, they are often burned in hospitals To sterilize and purify the air; the Moors believed that rosemary could drive away pests, so rosemary was planted in large quantities around the orchard. It can be seen from the above that people have a long history of developing and utilizing rosemary. Modern studies have shown ...