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A pharmaceutical preparation of Kangaiping and its preparation method

A technology of traditional Chinese medicine and extract, applied in the field of anticancer drug preparation and preparation thereof, can solve the problems of many impurities, large dosage, affecting clinical application, etc., and achieve the effect of clear curative effect, easy acceptance and high stability

Inactive Publication Date: 2019-02-01
姚娟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in practice, the drug is used as an ordinary pill, and the medicinal materials are powdered into medicine without any extraction, resulting in many impurities and large doses, which seriously affect its clinical application.

Method used

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  • A pharmaceutical preparation of Kangaiping and its preparation method
  • A pharmaceutical preparation of Kangaiping and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Preparation of traditional Chinese medicine extract

[0019] Get 1340 parts by weight of pearl vegetable, 1340 parts by weight of vine pear root, 1340 parts by weight of fragrant tea dish, 1340 parts by weight of sarcocarpus, 720 parts by weight of snakeberry, 1730 parts by weight of Scutellaria barbata, 720 parts by weight of orchid vanilla, snake tongue diffusa 720 parts by weight of grass, 720 parts by weight of cypress cypress and 3 parts by weight of toad venom.

[0020] (1) Preparation of the active ingredient of toad: take toad and crush it into coarse powder, add appropriate amount of ethanol to moisten it, put it into the percolation cylinder, add 10 times the amount of 90% ethanol to soak for 8 hours, and then percolate until the effluent For light color, collect percolation liquid, recover ethanol under reduced pressure, add 3 times the amount of ethanol to dissolve, add 0.1% activated carbon for decolorization, after decarbonization, filter, and recover the ...

Embodiment 2-4

[0026] Except the following table parameter, other are all the same as embodiment 1

[0027] parts by weight

Embodiment 5

[0028] The stability investigation of the traditional Chinese medicine granule prepared in embodiment 5 embodiment 1-4

[0029] According to the stability guidelines of the second appendix of the Chinese Pharmacopoeia 2010 edition, the stability of the relevant samples was investigated, and the stability of the drug was investigated at 25°C for 36 months, and at 25°C and a relative humidity of 75% for 60 days. The contents of isoxazinidine and scutellarin in traditional Chinese medicine granules were determined by HPLC.

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Abstract

The invention relates to a medicinal preparation and a preparation process thereof and particularly relates to an anti-cancer Chinese medicinal granule and a preparation process thereof. The Chinese medicinal granule is prepared from 80-120 parts by weight of a Chinese medicinal herb extract, 10-30 parts by weight of a filling agent, 5-10 parts by weight of a flavoring agent and 3-5 parts by weight of a lubricating agent, and the Chinese medicinal granule is preferentially prepared from 100 parts by weight of a Chinese medicinal herb extract, 20 parts by weight of a filling agent, 8 parts by weight of a flavoring agent and 4 parts by weight of a lubricating agent. The Chinese medicinal granule prepared by adopting the preparation process has a definite treatment effect, has high stability and is more acceptable to patients than a conventional pill.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation process thereof, in particular to a traditional Chinese medicine Kangaiping traditional Chinese medicine granule and a preparation process thereof. Background technique [0002] Cancer, also known as malignant tumor (Malignant neoplasm), is a disease caused by the abnormal mechanism of controlling cell growth and proliferation. In addition to growing out of control, cancer cells can also locally invade the surrounding normal tissues and even transfer to other parts of the body through the internal circulatory system or lymphatic system. Common cancers include gastric cancer, colon cancer, liver cancer, nasopharyngeal cancer, lung cancer, and intracranial tumors. [0003] At present, there are not many traditional Chinese medicine preparations that can be used clinically to treat digestive tract cancer. Among the 5017 preparations contained in the "New National Chines...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/85A61K9/16A61P35/00A61K35/65
CPCA61K9/1652A61K35/65A61K36/11A61K36/185A61K36/53A61K36/539A61K36/73A61K36/748A61K36/85A61K2300/00
Inventor 姚娟王爱玲葛明珠
Owner 姚娟