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A kind of production technology of boron citrate

A technology of boron citrate and production process, applied in the separation/purification of carboxylic acid compound, preparation of carboxylate, preparation of carboxylate, etc., can solve problems such as unpublished patent, inability to obtain boron citrate, etc., To achieve the effect of simple process

Active Publication Date: 2016-05-18
NANTONG FEIYU FINE CHEM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, there is no detailed information on the method of producing boron citrate in China, and there is no published patent. Boron citrate is mainly used as pharmaceutical raw materials or food additives, and the current general production method cannot obtain powdered boron citrate.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A kind of production technique of boron citrate, specifically comprises the steps:

[0017] a. Dehydrate boric acid at 220°C to make boron oxide;

[0018] b. Dissolve food-grade citric acid in water to form a citric acid aqueous solution with a concentration of 40%, and heat it to above 60°C;

[0019] c. Slowly add the boron oxide prepared in step a to the citric acid aqueous solution in step b to carry out neutralization reaction to generate boron citrate, and control the pH value of the reaction solution to 4;

[0020] d. The boron citrate prepared in step c is concentrated, cooled and crystallized, then poured into a blender and stirred for 25 minutes, and then put into a centrifugal dehydrator for centrifugal dehydration;

[0021] e. Send the dehydrated boron citrate into a drying oven at 85°C for 90 minutes to obtain boron citrate.

Embodiment 2

[0023] A kind of production technique of boron citrate, specifically comprises the steps:

[0024] a. Dehydrate boric acid at 240°C to produce boron oxide;

[0025] b. Dissolve food-grade citric acid in water to form a citric acid aqueous solution with a concentration of 45%, and heat it to above 60°C;

[0026] c. Slowly add the boron oxide prepared in step a to the citric acid aqueous solution in step b to carry out neutralization reaction to generate boron citrate, and control the pH value of the reaction solution to 7;

[0027] d. The boron citrate prepared in step c is concentrated, cooled and crystallized, then poured into a blender and stirred for 30 minutes, and then put into a centrifugal dehydrator for centrifugal dehydration;

[0028] e. Send the dehydrated boron citrate into a drying oven at 90°C for 95 minutes to obtain boron citrate.

Embodiment 3

[0030] A kind of production technique of boron citrate, specifically comprises the steps:

[0031] a. Dehydrate boric acid at 260°C to make boron oxide;

[0032] b. Dissolve food-grade citric acid in water to form a citric acid aqueous solution with a concentration of 50%, and heat it to above 60°C;

[0033] c. Slowly add the boron oxide prepared in step a to the citric acid aqueous solution in step b to carry out neutralization reaction to generate boron citrate, and control the pH value of the reaction solution to 8;

[0034] d. The boron citrate prepared in step c is concentrated, cooled and crystallized, then poured into a blender and stirred for 35 minutes, and then put into a centrifugal dehydrator for centrifugal dehydration;

[0035] e. Send the dehydrated boron citrate into a drying oven at 95°C for 100 minutes to obtain boron citrate.

[0036] Above-mentioned 3 embodiments all obtain product quality index and be:

[0037] Boron content 36~37.8%

[0038] Loss...

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Abstract

The invention discloses a production process of boron citrate. With copper carbonate or copper oxide as a raw material, the raw material reacts with edible citric acid to prepare boron citrate, and the boron citrate is further prepared by centrifugal dewatering and drying. The production process of boron citrate, disclosed by the invention, is simple, and the prepared boron citrate is high in purity and can be formed to powder.

Description

technical field [0001] The invention relates to the field of food and medicine raw materials, in particular to a production process of boron citrate. Background technique [0002] At present, there is no detailed information on the method of producing boron citrate in China, and there is no published patent. Boron citrate is mainly used as pharmaceutical raw materials or food additives, and the current general production method cannot obtain powdered boron citrate. . Contents of the invention [0003] Purpose of the invention: the purpose of this invention is to provide a kind of production technology of boron citrate in order to solve the deficiencies in the prior art, and a kind of powdery boron citrate can be prepared. [0004] The technical scheme adopted in the present invention: a production process of boron citrate, which uses boron oxide as a raw material to react with edible citric acid to prepare boron citrate, which is centrifuged and dehydrated and dried to ma...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07C59/265C07C51/41
CPCC07C51/412C07C51/42C07C59/265
Inventor 姚建飞朱碧君姚佼
Owner NANTONG FEIYU FINE CHEM