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A kind of processing method of Jianqu granule

A technology of granules and fine powders, which is applied in the processing of Jianqu granules, can solve the problems of unsatisfactory medication requirements, primitive processing technology, and difficulty in ensuring drug efficacy, etc., to facilitate mass mixed production, reduce process steps, and improve bioavailability degree of effect

Active Publication Date: 2017-11-28
SICHUAN BAISHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The invention discloses a processing technology and method of Jianqu granules, the purpose of which is to innovate a new processing technology and method of Jianqu on the basis of traditional Chinese medicine decoction pieces to obtain a new processing specification of Jianqu. In order to solve the problems that the existing Jianqu processing technology is primitive, the quality is rough, the drug effect is difficult to guarantee, the drug is inconvenient, and the drug demand cannot be met. The process and processing method include the following steps:

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] (1) Take 6.6g of Polygonum spicosa, 4.0g of bitter almond, 9.0g of hawthorn (fried), 6.0g of herb, 3.0g of Angelica dahurica, 6.0g of perilla, 1.5g of laurel, 21.2g of wheat bran, 6.6g of cocklebur, and red bean 4.0g, Chenpi 6.0g, Magnolia officinalis 3.0g, Betel nut 3.0g,

[0026] Mint 3.0g, Rhizoma Cyperi 6.0g, Artemisia annua 6.6g, Malt 9.0g, Patchouli 6.0g, Chuanxiang 3.0g, Citrus aurantium (stir-fried with bran) 3.0g, Guya 9.0g, Licorice 1.5g;

[0027] (2) Mix the drug in step (1) with 21.2 g of wheat bran, pulverize into the finest powder at 20°C, and sieve;

[0028] (3) Take 10.6g of flour and mix it evenly with the finest powder in step (2), and knead it into a ball by hand;

[0029] ⑷, put step ⑶ in a closed room, ferment in an environment with a temperature of 30-35°C and a humidity of 85-90% until white mold is everywhere, and take it out when there is a wine aroma;

[0030] (5) Granulate and dry the drug taken out in step (4) to obtain Jianqu Granules.

Embodiment 2

[0032] (1) Take 6.6g of Polygonum spicosa, 4.0g of bitter almond, 9.0g of hawthorn (fried), 6.0g of herb, 3.0g of Angelica dahurica, 6.0g of perilla, 1.5g of laurel, 21.2g of wheat bran, 6.6g of cocklebur, and red bean 4.0g, Chenpi 6.0g, Magnolia officinalis 3.0g, Betel nut 3.0g,

[0033] Mint 3.0g, Rhizoma Cyperi 6.0g, Artemisia annua 6.6g, Malt 9.0g, Patchouli 6.0g, Chuanxiang 3.0g, Citrus aurantium (stir-fried with bran) 3.0g, Guya 9.0g, Licorice 1.5g;

[0034] (2) Mix the drug in step (1) with 21.2 g of wheat bran, pulverize into the finest powder at 24°C, and sieve;

[0035] (3) Take 10.6g of flour and mix it evenly with the finest powder in step (2), and knead it into a ball by hand;

[0036] ⑷, put step ⑶ in a closed room, ferment in an environment with a temperature of 30-35°C and a humidity of 85-90% until white mold is everywhere, and take it out when there is a wine aroma;

[0037] (5) Granulate and dry the drug taken out in step (4) to obtain Jianqu Granules.

Embodiment 3

[0039] (1) Take 6.6g of Polygonum spicosa, 4.0g of bitter almond, 9.0g of hawthorn (fried), 6.0g of herb, 3.0g of Angelica dahurica, 6.0g of perilla, 1.5g of laurel, 21.2g of wheat bran, 6.6g of cocklebur, and red bean 4.0g, Chenpi 6.0g, Magnolia officinalis 3.0g, Betel nut 3.0g,

[0040] Mint 3.0g, Rhizoma Cyperi 6.0g, Artemisia annua 6.6g, Malt 9.0g, Patchouli 6.0g, Chuanxiang 3.0g, Citrus aurantium (stir-fried with bran) 3.0g, Guya 9.0g, Licorice 1.5g;

[0041] (2) Mix the drug in step (1) with 21.2 g of wheat bran, pulverize into the finest powder at 27°C, and sieve;

[0042] (3) Take 10.6g of flour and mix it evenly with the finest powder in step (2), and knead it into a ball by hand;

[0043] ⑷, put step ⑶ in a closed room, ferment in an environment with a temperature of 30-35°C and a humidity of 85-90% until white mold is everywhere, and take it out when there is a wine aroma;

[0044] (5) Granulate and dry the drug taken out in step (4) to obtain Jianqu Granules.

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Abstract

The invention discloses a method for processing Jianqu granules, which comprises the following steps: take 6.6g of Polygonum caperica, 4.0g of bitter almond, 9.0g of hawthorn (stir-fried), 6.0g of Atractylodes atractylodes, 3.0g of Angelica dahurica, 6.0g of perilla, and Guangui 1.5g, 21.2g wheat bran, 6.6g cocklebur, 4.0g red bean, 6.0g tangerine peel, 3.0g magnolia bark, 3.0g betel nut, 3.0g mint, 6.0g Cyperus cyperi, 6.6g artemisia annua, 9.0g malt, 6.0g of Huoxiang, 3.0g of Chuanxiang, 3.0g of Citrus aurantii (stir-fried with bran), 9.0g of grain buds, 1.5g of licorice and 21.2g of wheat bran, and grind them into the finest powder at a low temperature of 20°C~30°C. Sieve; take 10.6g of flour and mix it evenly with the finest powder, put it in a closed room, and ferment it in an environment with a temperature of 30-35°C and a humidity of 85-90% until white mold appears all over the place. Qu granules; this Jianqu granule can be directly ingested without crushing or decocting, which reduces the difficulty of taking medicine. It does not need to decoct when taking medicine, which reduces the loss of active ingredients of the medicine. At the same time, in the production process, the medicinal materials are crushed into the finest powder , improve the availability of the drug, which is beneficial to the release of the drug and the absorption of the drug by the human body.

Description

technical field [0001] The invention relates to the field of medicine preparation, in particular to a method for preparing Jianqu granules. Background technique [0002] Jianqu is recorded in the page number Z17-142 in the drug standard of the Ministry of Health of the People's Republic of China "Prescriptions of Traditional Chinese Medicine" (Volume 17). Mainly used for cold and heat headache, food stagnation, vomiting and fullness. Its preparation method is to crush bitter almonds, atractylodes, angelica and other twenty-one herbs into fine powder, mix them with wheat bran evenly, sieve, then make the flour into a thin paste, and mix it with the above-mentioned medicinal powder while it is hot, and make it into cubes , ferment until the medicine block is covered with white mold and has the aroma of wine, take it out and dry it. At the same time, the traits of Jianqu prepared according to the standard "Quality Standards for Jianqu" (standard code WS-B-3238-98) promulgated...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K36/8998
Inventor 罗明
Owner SICHUAN BAISHENG PHARMA