Multivitamin and mineral tablet and mixing granulation technology thereof

Abstract

The invention provides a multivitamin and mineral tablet and a mixing granulation technology thereof. The mixing granulation technology comprises the following steps: A dividing main medicines into 12 groups according to the physicochemical properties of the main medicines in the multivitamin and mineral tablet; B dissolving and stirring the main medicines of which the content is smaller than one-hundred-thousandth of weight of the medicines to form a solution; C adding an adhesive to the solution, mixing and forming a uniform mixture; D operating the 12 groups of main medicines according to the methods in the steps A, B and C, respectively adding corresponding auxiliary materials to each group of mixture, respectively adding to a high-speed mixing granulator, and carrying out mixing granulation, so as to form 1-12 groups of uniform particles; and E drying the 1-12 groups of particles, adding to a two-dimensional mixing machine, carrying out total mixing, tabletting and coating. According to the method, raw materials are effectively saved; the mixing frequency is reduced; the pollution risk is reduced; and the requirements of GMP (good manufacturing practice) are met.

Description

technical field [0001] The invention relates to a preparation technology of a multidimensional element tablet, in particular to a multidimensional element tablet and a mixing and granulation process thereof. Background technique [0002] Multi-dimensional element tablet (21) is the first vitamin product recommended by the China Nutrition Association. The earliest multi-dimensional element tablet used in China was developed and launched in 1984. It has been selling well so far. It is an over-the-counter Class B drug and a formula suitable for Chinese people. . This product can effectively treat vitamin and trace element deficiency, and is widely used in orthopedics, pediatrics, gynecology, neurology, etc. It also has a clear effect in improving the body's immunity and resisting viruses such as colds. [0003] The key technical process in the production process of the multi-dimensional element tablet (21) is mixing and granulating. Uneven mixing will directly lead to uneven d...

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Problems solved by technology

[0005] In view of the shortcomings of the above-mentioned prior art, the purpose of the present invention is to provide a multi-dimensional element tablet and its mixing granulation process, aiming to solve the problems of poor mixing effect and cumbersome mixing methods in the existing production process

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