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Stable and efficient chlortetracycline hydrochloride soluble powder for livestock and preparation technology thereof

A chlortetracycline hydrochloride, soluble technology, applied in the field of veterinary chlortetracycline hydrochloride soluble powder and its preparation technology, can solve the problems of instability, discoloration, easy oxidation and the like of chlortetracycline, so as to increase cell transport and promote drug absorption , the effect of improving the absorption rate and bioavailability

Inactive Publication Date: 2015-06-24
CP UNITED ANIMAL PHARMA TECH JIANGSU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, the veterinary chlortetracycline hydrochloride soluble powder sold on the market is unstable, easy to oxidize, and discolored, which has a great impact on the stability and therapeutic effect of the preparation. Therefore, it is urgent to develop a stable and efficient Chlortetracycline hydrochloride soluble powder and its preparation process

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1: first take by weighing aureomycin hydrochloride 10kg after sieving, lauryl sulfate sodium salt 0.2kg, edetate disodium salt 0.1kg, anhydrous glucose 89.7kg, again with equal amount increasing method After fully mixing for 0.5 hour, the highly efficient and stable veterinary aureomycin hydrochloride soluble powder of the present invention is obtained.

Embodiment 2

[0015] Embodiment 2: first take by weighing aureomycin hydrochloride 15kg after sieving, lauryl sulfate sodium salt 0.3kg, ethylenediaminetetraacetic acid disodium salt 0.2kg, anhydrous glucose 84.5kg, again with equal amount increasing method After fully mixing for 0.8 hours, the chlortetracycline hydrochloride soluble powder is obtained.

Embodiment 3

[0016] Embodiment 3: first take by weighing 20kg of aureomycin hydrochloride after sieving, 2kg of sodium lauryl sulfate, 0.6kg of disodium salt of edetate, 77.4kg of anhydrous glucose, then fully After mixing for 1 hour, the aureomycin hydrochloride soluble powder was obtained.

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PUM

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Abstract

The invention discloses stable and efficient chlortetracycline hydrochloride soluble powder for livestock and a preparation technology thereof. The powder mainly comprises the following raw materials in percentage by weight: 10-15 percent of chlortetracycline hydrochloride, 0.2-3.0 percent of lauryl sodium sulfate, 0.1-1.0 percent of ethylenediamine tetraacetic acid disodium and anhydrous dextrose in balancing amount. The raw materials are crushed and screened respectively, and then are fully and uniformly mixed by an equivalent incremental method. According to the powder, chlortetracycline hydrochloride is adopted as a raw material, lauryl sodium sulfate is added as an absorption promoter, and ethylenediamine tetraacetic acid disodium salt is added as an antioxidant and a chelating agent, so that the stability and high efficiency of the chlortetracycline hydrochloride soluble powder are guaranteed.

Description

technical field [0001] The invention relates to a chlortetracycline hydrochloride soluble powder, in particular to a stable and efficient veterinary chlortetracycline hydrochloride soluble powder and a preparation process thereof. Background technique [0002] At present, the veterinary chlortetracycline hydrochloride soluble powder sold on the market is unstable, easy to oxidize, and discolored, which has a great impact on the stability and therapeutic effect of the preparation. Therefore, it is urgent to develop a stable and efficient Chlortetracycline hydrochloride soluble powder and its preparation process. Contents of the invention [0003] Aiming at the above existing technical problems, the present invention provides a stable and efficient veterinary chlortetracycline hydrochloride soluble powder and its preparation process, so as to achieve the purposes of high efficiency, stability, fast absorption and safe use. [0004] In order to achieve the above object, the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K31/65A61K47/20A61K47/18
Inventor 田勇熊天飞刘奎山张喜王真真李宁
Owner CP UNITED ANIMAL PHARMA TECH JIANGSU
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