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Adjuvant drug for postural vertigo calculus restoration

A technology for displacement vertigo and adjuvant medication, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc. It can solve the problem of lack of drugs to increase the efficiency of CRT, inability to resist head position changes, and limited clinical application And other problems, to achieve the effect of reducing the chance of recurrence after treatment, preventing further accumulation, and increasing transdermal absorption

Inactive Publication Date: 2015-07-01
王高临
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method works well for fluid "semicircular canal stones", but for "ampullary crest stones", the clinical application of CRT is not widespread due to the following factors: ① The deposited "denatured otoliths" are a kind of basophilic Inflammatory granules are not pure calcium carbonate particles in semicircular canal stones, so they are highly aggregated, firmly adhered, and difficult to flow; ② patients with semicircular canal stones have a latency period of 3 to 40 seconds for vertigo after the excitation head position, while pot The positional vertigo caused by abdominal crest calculi occurs immediately without a latent period. Therefore, during CRT operation, the latter has a strong feeling of vertigo, which leads to the failure of manual reset
Therefore, it has been reported in the literature that the effective rates of CRT in the treatment of "semicircular canal stones" and "ampullary crest stones" are 92% and 63%, respectively, and 41% of patients with "ampullary crest stones" are unable to fight head pain in CRT treatment. change in position leading to discontinuation of treatment
[0004] At present, the adjuvant drugs used for CRT mainly start with "vertigo", aim at "phlegm turbidity", and are mostly used for the residual vertigo after the repositioning of tube stones, and there is still a lack of drugs to increase the effective rate of CRT

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1, the weight ratio of raw materials: 2 parts of mole crickets, 12 parts of stinky Artemisia chinensis, 12 parts of passionflower, 15 parts of ground tiger, 15 parts of purslane, 15 parts of root, 15 parts of eucalyptus, 15 parts of seven tendons 1 serving of aunt, 15 servings of lotus root, 12 servings of Baiwei, 20 servings of chicken head rice.

[0034] The preparation method of Example 1 is: mix mole cricket, scorpion root, stinky wormwood, lotus nelum, passion flower, scutellaria oleracea, purslane, luan osmanthus, Qijingu, Baiwei, chicken head rice and add 10 times Measure water and decoct twice, 1 hour each time, filter the extract, combine, and stand still for 24 hours, take the supernatant and filter it with a 0.4 μm filter membrane, concentrate the filtrate into a thick paste, dry it under reduced pressure, and crush it through a 150-mesh sieve , into fine powder. The resulting fine powder is used for ear blowing.

Embodiment 2

[0035] Example 2, the weight ratio of raw materials: 1 part of mole cricket, 3 parts of stinky Artemisia chinensis, 3 parts of passionflower, 12 parts of ground tiger, 12 parts of purslane, 12 parts of root, 12 parts of eucalyptus, seven tendons 1 part of aunt, 12 parts of lotus root, 3 parts of Baiwei, 1 part of fir leaf, and 10 parts of chicken head rice.

Embodiment 3

[0036] Example 3, the weight ratio of raw materials: 2 parts of mole crickets, 12 parts of Artemisia stifolium, 12 parts of passionflower, 15 parts of tiger lily, 15 parts of purslane, 15 parts of root, 15 parts of eucalyptus, seven tendons 1 part of aunt, 15 parts of lotus root, 12 parts of Bai Wei, 2 parts of fir leaf, 20 parts of chicken head rice.

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PUM

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Abstract

The invention discloses an adjuvant drug for postural vertigo calculus restoration to solve the problem of treating postural vertigo. The adjuvant drug is characterized by being prepared from the raw medicinal materials of African mole cricket, oriental grape root, sweet wormwood herb, lotus stamen, herb of passionflower, strict botrypus, shaggy portulaca, pluchea indica, Clintonia udensis, leaf of Chinese fir, blackend swallowwort root and gorgon fruit. A clinical experiment proves that the adjuvant drug has the characteristics of good curative effect and relatively high safety for treating postural vertigo and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to an auxiliary medicine for the reduction of displacement vertigo stones. Background technique [0002] Epidemiological statistics show that the top three most common diseases in neurology clinics are migraine, variable vertigo, and depression / anxiety disorders. The so-called "displacement vertigo" refers to the short-term paroxysmal vertigo and nystagmus that occurs when the head moves rapidly to a specific head position. It is very common in vertigo diseases. 20% to 40% of all peripheral vertigo received, accounting for 9% of the elderly population, the incidence rate of women is about 1.6-2:1 higher than that of men. The pathological factor of displacement vertigo lies in the tiny particles attached to the enlarged part of the semicircular canal of the inner ear, the "ampullary", commonly known as "otoliths". Displacement vertigo can be divided into semicircular ca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P1/08A61P25/00A61K35/64
Inventor 王高临杜得杰
Owner 王高临