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Plant vacant capsule compounded from cellulose gum and red alga KAPPA gum and preparation method thereof

The technology of plant hollow capsule and red algae carpa gum is applied in the field of medicine, and can solve the problems of slow disintegration rate of plant capsules, poor film-forming property and storage stability of plant capsules, adverse effects of drugs, and the like.

Inactive Publication Date: 2015-07-08
CHINA BIOENG LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are many patent applications for plant hard capsules, but the plant capsules provided by them obviously have the defect of slow disintegration speed, and at the same time, the film-forming properties and storage stability of the plant capsules are poor, which has adverse effects on certain drugs in the capsules.

Method used

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Examples

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Comparison scheme
Effect test

Embodiment Construction

[0016] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0017] Red algae KAPPA glue is a water-soluble polysaccharide extracted from red algae, which has the characteristics of thickening, gelation and film-forming, especially when the cellulose glue and red algae KAPPA glue are compounded, the synergistic effect is the best, which can Increase the toughness and elasticity of the capsule, so the red algae KAPPA glue has become one of the important raw materials for the production of vegetable capsule shells.

[0018] The advantage of using hydroxypropyl methylcellulose HPMC is that the strength and softness of HPMC are very stable, and there is basically no hygroscopic effect. HPMC has suitable water solubility, thermal gelation, thickening, film forming and emulsifying properties. Its main chemical property is that it swells in cold water and then dissolves, and forms a gel when the temp...

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Abstract

The invention provides a plant vacant capsule compounded from cellulose gum and red alga KAPPA gum and a preparation method thereof. The plant vacant capsule includes following components, by weight: 88-90% of a compounded gum of cellulose gum and red alga KAPPA gum, 1-3% of potassium chloride, 0-0.2% of a sulfite, 3-5% of medicinal glycerin and 2-3% of titanium dioxide. The compounded gum of cellulose gum and red alga KAPPA gum is a mixture composed of carboxymethyl cellulose salt SCMC, hydroxypropyl methyl cellulose HPMC and the red alga KAPPA gum according to the weight ratio of 8:80:12. The plant vacant capsule compounded from the cellulose gum and the red alga KAPPA gum is quick in disintegration speed and is good in film forming property and storage stability.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a plant hollow capsule manufactured by compounding cellulose gum and red algae kappa gum and a preparation method thereof. Background technique [0002] Capsules have been officially listed as pharmaceutical excipients by the country and have been widely used in the hospital field. Drugs packed in capsules are generally powders or granules that are irritating to the esophagus and gastric mucosa, or drugs that taste bad, are easy to volatilize, are easily decomposed by saliva in the mouth, and are easy to inhale into the trachea. These medicines are packed into capsules, which not only protects the properties of the medicine from being destroyed, but also protects the digestive organs and respiratory tract. Capsules are divided according to raw materials, and capsules generally include gelatin capsules and vegetable capsules. Most capsules in use today are made of gelatin, the main mater...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K47/38A61K47/36
CPCA61K9/48A61K47/36A61K47/38
Inventor 郭卫强庄永竞赵立新
Owner CHINA BIOENG LTD
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