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Medicine for treating liver cirrhosis and preparation method thereof

The technology of a medicine and an extract is applied in the field of medicines with significant curative effect in the treatment of liver cirrhosis and the preparation field thereof, and can solve the problems of limited curative effect and the like

Active Publication Date: 2015-07-08
安堂娥
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these drugs have certain curative effects clinically, but the actual curative effect is limited due to various reasons.

Method used

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  • Medicine for treating liver cirrhosis and preparation method thereof
  • Medicine for treating liver cirrhosis and preparation method thereof
  • Medicine for treating liver cirrhosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Prescription and technology of medicine making capsule of the present invention:

[0028]

[0029] Extraction of the Phnom Penh leech extract: take the whole Phnom Penh leech, crush it into a coarse powder, soak the coarse powder with 6-10 times the amount of salt water at a temperature of 2-20°C for 12 hours, filter the liquid, and collect the filtrate;

[0030] Add 10-40% trichloroacetic acid to the collected filtrate to make the pH of the filtrate 2.5, centrifuge and precipitate with a centrifuge, collect the supernatant, ultrafilter the supernatant with an ultrafiltration machine, and freeze-dry the filtrate to obtain the extract;

[0031] Extraction of curcuma, knotweed, chrysanthemum, angelica, Alisma, banzhilian and Tuyuan extracts: add 6 to 12 times the amount of water, steam twice, the first time is 40 minutes, and the second time is 40 minutes. After 30 minutes, the liquid was left to stand, and the supernatant was concentrated and ethanol-precipitated, and...

Embodiment 2

[0034] The prescription and the technology that pharmaceutical composition of the present invention makes tablet:

[0035]

[0036] The extraction method is the same as above, and the tablet process is as follows: take the extracts of Phnom Penh leech, Polygonum cuspidatum and other seven herbs, use hydroxypropyl cellulose as a binder, make soft materials, granulate, dry, granulate, and compress into tablets.

Embodiment 3

[0038] Prescription and process for making dripping pills:

[0039]

[0040] The extraction method is the same as above, and the process of making drop pills is as follows: take polyethylene glycol 6000 and heat and dissolve it on a 90°C oil tank, add Phnom Penh leech extract, earthworm extract, astragalus root and earth element extract, stir to dissolve, and then move to the liquid storage tank Insulated at 80°C. Adjust the drop valve, drop into liquid paraffin at 10-15°C to form pellets, drain the pellets, and dry to obtain.

[0041] The present invention adopts the preparation technology in the existing medical field, and the above-mentioned composition can be made into various pharmaceutical dosage forms suitable for clinical application:

[0042] Pharmaceutical composition of the present invention shows that its test and result are as follows through pharmacodynamic research:

[0043] Materials and instruments:

[0044]Drugs and Reagents The drug extract of the pres...

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PUM

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Abstract

The invention discloses a medicine for treatment of liver cirrhosis and a preparation method thereof. The medicine is composed of the following components by weight: 10 to 60 parts of gilt-edged leech, 20 to 80 parts of zedoary, 10 to 50 parts of giant knotweed, 4 to 35 parts of Polygala fallax Hemsl, 4 to 30 parts of Chinese angelica, 5 to 30 parts of Alisma Orientalis, 5 to 40 parts of barbat skullcap and 5 to 80 parts of ground beetle. Though combined usage of the above-mentioned bulk drugs, the medicine provided by the invention is capable of dredging a dragon path and a fire path, curing diseases due to noxious agents produced by various parasites, eliminating damp toxin, dredging a water passage and conditioning and tonifying both qi and blood, so liver cirrhosis is self-cured.

Description

technical field [0001] The invention relates to a medicine for treating liver disease. More specifically, the present invention relates to a medicine with significant curative effect on treating liver cirrhosis and a preparation method thereof. Background technique [0002] Liver cirrhosis is a very common chronic, diffuse, progressive fibrous lesion that can be caused by one or more causes, or other unknown causes of liver damage. The specific manifestations are diffuse necrosis of liver cells, fibrous tissue hyperplasia and nodular regeneration of liver cells. These three changes are repeatedly interlaced. There is currently no effective treatment. [0003] The key to the cause of liver cirrhosis is the dysfunction of liver, spleen and kidney. Liver qi stagnation and qi stagnation lead to venous obstruction is a basic factor in the formation of liver cirrhosis. Secondly, the function of the spleen is damaged, and the transportation and transformation are neglected, whi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/16A61K35/64A61K35/62
Inventor 宋延坤许振朝黄俊张雄胜宋茹雪
Owner 安堂娥
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