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Tinospora sinensis Merr extract, and extraction method and application thereof

An extraction method and extract technology, which are applied in the field of extracts of the vines and its extraction, can solve the problems of no anti-hyperuricemia and gout treatment effects, and achieve clear industrialization prospects, abundant drug resources, and raw materials. Easy-to-source effects

Active Publication Date: 2015-07-15
广西卫生职业技术学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Tinospora sinensis (Lour.) Merr is the cane of Tinospora sinensis (Lour.) Merr, a plant of the genus Tinospora sinensis (Lour.) Merr. Literature reports on anti-hyperuricemia and treatment of gout

Method used

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  • Tinospora sinensis Merr extract, and extraction method and application thereof
  • Tinospora sinensis Merr extract, and extraction method and application thereof
  • Tinospora sinensis Merr extract, and extraction method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Take 1000g of broad tendon rattan, sieve and crush it with a 12-mesh sieve, then add 7L of cold water to soak for 100min, then heat to boil, keep boiling for 100min, and filter; add 5L of water to the filtered medicinal residue Continue to decoct, keep boiling for 100 minutes, and filter; add 5 L of water to the filtered dregs to continue decocting, keep boiling for 70 minutes, filter; combine the decocted liquid, and concentrate in a water bath to form a paste. Put the concentrated paste into the resin column, elute with water first, then elute with the eluent with 30%-100% ethanol volume concentration, collect the eluate with 60% ethanol volume concentration, concentrate into a paste, and obtain the extract things.

Embodiment 2

[0032] Take 1000g of broad tendon rattan, sieve and crush it with a 5-mesh sieve, add 9L of cold water to soak for 60 minutes, then heat to boil, keep boiling for 150 minutes, and filter; add 4L of water to the filtered medicinal residue and continue to decoct Boil, keep boiling for 120 minutes, filter; add 3L water to the filtered dregs to continue decocting, keep boiling for 90 minutes, filter; combine the decocted liquid, concentrate in a water bath to form a paste. Put the concentrated paste into the resin column, elute with water first, then elute with eluent with volume concentration of 30%-100% ethanol, collect the eluate with volume concentration of 70% ethanol, concentrate into paste, and obtain the extract things.

Embodiment 3

[0034] Take 1000g of broad tendon rattan, sieve and crush it with 20-mesh sieve, add 5L of cold water to soak for 100min, then heat to boil, keep boiling for 60min, and filter; add 7L of water to the filtered medicinal residue and continue to decoct Boil, keep boiling for 40 minutes, filter; add 5L of water to the filtered dregs to continue decocting, keep boiling for 40 minutes, filter; combine the decocted liquid, concentrate in a water bath to form a paste. The concentrated ointment macroporous resin column is firstly eluted with water, and then eluted with an eluent with a volume concentration of 30%-100%, and the eluent with a volume concentration of 50% ethanol is collected and concentrated into a paste to obtain the extract .

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Abstract

The invention specifically relates to a Tinospora sinensis Merr extract, and an extraction method and application thereof, belonging to the technical field of natural extracts. The extraction method for the Tinospora sinensis Merr extract comprises multiple water extraction and elution with ethanol. According to the invention, resources for extraction of the Tinospora sinensis Merr extract are abundant; the extraction method is simple and feasible; raw materials are conveniently and easily available; and the method is applicable to large-scale preparation of the Tinospora sinensis Merr extract, has low cost and small pollution, facilitates large-scale preparation under the conditions of energy saving and emission reduction and has clear industrial prospects. The Tinospora sinensis Merr extract has a plurality of purposes and can be applied to food, health products, preparation of drugs used for treating special diseases, etc.; and scientific support is provided for clinical application of the Tinospora sinensis Merr extract in prevention or treatment of hyperuricemia and gout caused by hyperuricemia.

Description

technical field [0001] The invention belongs to the technical field of natural extracts, and in particular relates to an extract of vine vine and its extraction method and application. Background technique [0002] Gout is a disease of tissue damage caused by long-term purine metabolism disorders and increased blood uric acid, especially acute characteristic arthritis and chronic tophi diseases, mainly including acute-onset arthritis, tophi formation, and chronic tophi Arthritis, urate nephropathy, and uric acid urolithiasis; in severe cases, renal uric acid stones and gouty renal parenchymal lesions may appear later in the course of the disease. According to statistics, 20% to 25% of gout patients suffer from uric acid nephropathy, and it has been confirmed by autopsy that almost 100% of patients with nephropathy, and gout is often accompanied by abdominal obesity, hyperlipidemia, hypertension, type 2 diabetes and manifestations of cardiovascular disease. [0003] The typ...

Claims

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Application Information

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IPC IPC(8): A61K36/59A61P19/06
Inventor 张柯媛伍冠一唐宗湘周小雅熊灏覃艺群刘安韬刘喜华
Owner 广西卫生职业技术学院
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